English
Related papers

Related papers: Single-Cell Multimodal Prediction via Transformers

200 papers

Transformers, adapted from natural language processing, are emerging as a leading approach for graph representation learning. Contemporary graph transformers often treat nodes or edges as separate tokens. This approach leads to…

Machine Learning · Computer Science 2023-10-04 Zihan Pengmei , Zimu Li , Chih-chan Tien , Risi Kondor , Aaron R. Dinner

Single-cell RNA sequencing (scRNA-seq) enables high-resolution analysis of cellular heterogeneity, but its complexity, which is marked by high dimensionality, sparsity, and batch effects, which poses major computational challenges.…

Computation and Language · Computer Science 2026-03-25 Cong Qi , Hanzhang Fang , Siqi Jiang , Xun Song , Tianxing Hu , Wei Zhi

The use of multimodal data in assisted diagnosis and segmentation has emerged as a prominent area of interest in current research. However, one of the primary challenges is how to effectively fuse multimodal features. Most of the current…

Computer Vision and Pattern Recognition · Computer Science 2024-04-26 Xinxin Fan , Lin Liu , Haoran Zhang

The versatility of self-attention mechanism earned transformers great success in almost all data modalities, with limitations on the quadratic complexity and difficulty of training. To apply transformers across different data modalities,…

Machine Learning · Computer Science 2024-08-20 Viet Anh Nguyen , Minh Lenhat , Khoa Nguyen , Duong Duc Hieu , Dao Huu Hung , Truong Son Hy

Traditional vision-based material perception methods often experience substantial performance degradation under visually impaired conditions, thereby motivating the shift toward non-visual multimodal material perception. Despite this,…

Machine Learning · Computer Science 2025-11-26 Kailin Lyu , Long Xiao , Jianing Zeng , Junhao Dong , Xuexin Liu , Zhuojun Zou , Haoyue Yang , Lin Shu , Jie Hao

Predicting the future behavior of agents is a fundamental task in autonomous vehicle domains. Accurate prediction relies on comprehending the surrounding map, which significantly regularizes agent behaviors. However, existing methods have…

Computer Vision and Pattern Recognition · Computer Science 2024-01-19 Chen Feng , Hangning Zhou , Huadong Lin , Zhigang Zhang , Ziyao Xu , Chi Zhang , Boyu Zhou , Shaojie Shen

Multimodal learning aims to build models that can process and relate information from multiple modalities. Despite years of development in this field, it still remains challenging to design a unified network for processing various…

Computer Vision and Pattern Recognition · Computer Science 2023-07-21 Yiyuan Zhang , Kaixiong Gong , Kaipeng Zhang , Hongsheng Li , Yu Qiao , Wanli Ouyang , Xiangyu Yue

Multi-modal entity alignment (MMEA) aims to discover identical entities across different knowledge graphs (KGs) whose entities are associated with relevant images. However, current MMEA algorithms rely on KG-level modality fusion strategies…

Artificial Intelligence · Computer Science 2023-08-01 Zhuo Chen , Jiaoyan Chen , Wen Zhang , Lingbing Guo , Yin Fang , Yufeng Huang , Yichi Zhang , Yuxia Geng , Jeff Z. Pan , Wenting Song , Huajun Chen

The transformers have achieved significant accomplishments in the natural language processing as its outstanding parallel processing capabilities and highly flexible attention mechanism. In addition, increasing studies based on transformers…

Computation and Language · Computer Science 2024-07-19 Wei Lan , Guohang He , Mingyang Liu , Qingfeng Chen , Junyue Cao , Wei Peng

Survival outcome assessment is challenging and inherently associated with multiple clinical factors (e.g., imaging and genomics biomarkers) in cancer. Enabling multimodal analytics promises to reveal novel predictive patterns of patient…

Computer Vision and Pattern Recognition · Computer Science 2023-07-25 Kexin Ding , Mu Zhou , Dimitris N. Metaxas , Shaoting Zhang

Spatio-temporal traffic forecasting is challenging due to complex temporal patterns, dynamic spatial structures, and diverse input formats. Although Transformer-based models offer strong global modeling, they often struggle with rigid…

Artificial Intelligence · Computer Science 2025-08-20 Jiayu Fang , Zhiqi Shao , S T Boris Choy , Junbin Gao

Predicting human mobility holds significant practical value, with applications ranging from enhancing disaster risk planning to simulating epidemic spread. In this paper, we present the GeoFormer, a decoder-only transformer model adapted…

Machine Learning · Computer Science 2023-11-10 Aivin V. Solatorio

In the realm of Graph Neural Networks (GNNs), two exciting research directions have recently emerged: Subgraph GNNs and Graph Transformers. In this paper, we propose an architecture that integrates both approaches, dubbed Subgraphormer,…

Machine Learning · Computer Science 2024-05-29 Guy Bar-Shalom , Beatrice Bevilacqua , Haggai Maron

Spatially resolved transcriptomics brings exciting breakthroughs to single-cell analysis by providing physical locations along with gene expression. However, as a cost of the extremely high spatial resolution, the cellular level spatial…

Genomics · Quantitative Biology 2024-02-19 Hongzhi Wen , Wenzhuo Tang , Wei Jin , Jiayuan Ding , Renming Liu , Xinnan Dai , Feng Shi , Lulu Shang , Hui Liu , Yuying Xie

Cancer clinics capture disease data at various scales, from genetic to organ level. Current bioinformatic methods struggle to handle the heterogeneous nature of this data, especially with missing modalities. We propose PARADIGM, a Graph…

Cell Behavior · Quantitative Biology 2024-11-22 Asim Waqas , Aakash Tripathi , Paul Stewart , Mia Naeini , Matthew B. Schabath , Ghulam Rasool

The remarkable success of foundation models has sparked growing interest in their application to single-cell biology. Models like Geneformer and scGPT promise to serve as versatile tools in this specialized field. However, representing a…

Quantitative Methods · Quantitative Biology 2024-11-12 Jiabei Cheng , Jiachen Li , Kaiyuan Yang , Hongbin Shen , Ye Yuan

Single-cell RNA sequencing (scRNA-seq) enables single-cell transcriptomic profiling, revealing cellular heterogeneity and rare populations. Recent deep learning models like Geneformer and Mouse-Geneformer perform well on tasks such as…

Genomics · Quantitative Biology 2025-07-11 Yuki Nishio , Takayoshi Yamashita , Keita Ito , Tsubasa Hirakawa , Hironobu Fujiyoshi

The advent of single-cell technology has significantly improved our understanding of cellular states and subpopulations in various tissues under normal and diseased conditions by employing data-driven approaches such as clustering and…

Graph Neural Networks (GNNs) are widely used in graph data mining tasks. Traditional GNNs follow a message passing scheme that can effectively utilize local and structural information. However, the phenomena of over-smoothing and…

Machine Learning · Computer Science 2025-04-14 Zijie Zhou , Zhaoqi Lu , Xuekai Wei , Rongqin Chen , Shenghui Zhang , Pak Lon Ip , Leong Hou U

Accurate trajectory prediction is crucial for ensuring safe and efficient autonomous driving. However, most existing methods overlook complex interactions between traffic participants that often govern their future trajectories. In this…

Artificial Intelligence · Computer Science 2024-05-08 Zixu Wang , Zhigang Sun , Juergen Luettin , Lavdim Halilaj