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Detecting and classifying lesions in breast ultrasound images is a promising application of artificial intelligence (AI) for reducing the burden of cancer in regions with limited access to mammography. Such AI systems are more likely to be…

Computer Vision and Pattern Recognition · Computer Science 2024-07-02 Arianna Bunnell , Yannik Glaser , Dustin Valdez , Thomas Wolfgruber , Aleen Altamirano , Carol Zamora González , Brenda Y. Hernandez , Peter Sadowski , John A. Shepherd

Concept bottleneck models (CBMs) are inherently interpretable models that make predictions based on human-understandable visual cues, referred to as concepts. As obtaining dense concept annotations with human labeling is demanding and…

Computer Vision and Pattern Recognition · Computer Science 2025-08-21 Sujin Jeon , Hyundo Lee , Eungseo Kim , Sanghack Lee , Byoung-Tak Zhang , Inwoo Hwang

While deep learning models often lack interpretability, concept bottleneck models (CBMs) provide inherent explanations via their concept representations. Moreover, they allow users to perform interventional interactions on these concepts by…

Machine Learning · Computer Science 2024-06-05 David Steinmann , Wolfgang Stammer , Felix Friedrich , Kristian Kersting

Radiomics analysis has achieved great success in recent years. However, conventional Radiomics analysis suffers from insufficiently expressive hand-crafted features. Recently, emerging deep learning techniques, e.g., convolutional neural…

Image and Video Processing · Electrical Eng. & Systems 2019-10-22 Jiancheng Yang , Rongyao Fang , Bingbing Ni , Yamin Li , Yi Xu , Linguo Li

Deep Neural Networks (DNNs) are often considered black boxes due to their opaque decision-making processes. To reduce their opacity Concept Models (CMs), such as Concept Bottleneck Models (CBMs), were introduced to predict human-defined…

Human-Computer Interaction · Computer Science 2025-12-02 Jack Furby , Dan Cunnington , Dave Braines , Alun Preece

Concept bottleneck models (CBMs) have emerged as critical tools in domains where interpretability is paramount. These models rely on predefined textual descriptions, referred to as concepts, to inform their decision-making process and offer…

Computer Vision and Pattern Recognition · Computer Science 2024-06-14 Maor Dikter , Tsachi Blau , Chaim Baskin

Concept Bottleneck Models (CBMs) provide explicit interpretations for deep neural networks through concepts and allow intervention with concepts to adjust final predictions. Existing CBMs assume concepts are conditionally independent given…

Machine Learning · Computer Science 2026-05-04 Haotian Xu , Tsui-Wei Weng , Lam M. Nguyen , Tengfei Ma

In intensive care units (ICUs), critically ill patients are monitored with electroencephalograms (EEGs) to prevent serious brain injury. The number of patients who can be monitored is constrained by the availability of trained physicians to…

Interpretable deep learning aims at developing neural architectures whose decision-making processes could be understood by their users. Among these techniqes, Concept Bottleneck Models enhance the interpretability of neural networks by…

Machine Learning · Computer Science 2024-05-28 Gabriele Dominici , Pietro Barbiero , Francesco Giannini , Martin Gjoreski , Marc Langhenirich

Concept Bottleneck Models (CBMs) enhance interpretability by predicting human-understandable concepts as intermediate representations. However, existing CBMs often suffer from input-to-concept mapping bias and limited controllability, which…

Computer Vision and Pattern Recognition · Computer Science 2026-04-10 Gaoxiang Huang , Songning Lai , Yutao Yue

Concept bottleneck models (CBM) are a popular way of creating more interpretable neural networks by having hidden layer neurons correspond to human-understandable concepts. However, existing CBMs and their variants have two crucial…

Machine Learning · Computer Science 2023-06-06 Tuomas Oikarinen , Subhro Das , Lam M. Nguyen , Tsui-Wei Weng

The lack of transparency in the decision-making processes of deep learning systems presents a significant challenge in modern artificial intelligence (AI), as it impairs users' ability to rely on and verify these systems. To address this…

Artificial Intelligence · Computer Science 2024-11-18 David Debot , Pietro Barbiero , Francesco Giannini , Gabriele Ciravegna , Michelangelo Diligenti , Giuseppe Marra

Concept Bottleneck Models (CBMs) provide inherent interpretability by first predicting a set of human-understandable concepts and then mapping them to labels through a simple classifier. While users can intervene in the concept space to…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Hangzhou He , Lei Zhu , Kaiwen Li , Xinliang Zhang , Jiakui Hu , Ourui Fu , Zhengjian Yao , Yanye Lu

Digital mammography is essential to breast cancer detection, and deep learning offers promising tools for faster and more accurate mammogram analysis. In radiology and other high-stakes environments, uninterpretable ("black box") deep…

Computer Vision and Pattern Recognition · Computer Science 2024-06-11 Julia Yang , Alina Jade Barnett , Jon Donnelly , Satvik Kishore , Jerry Fang , Fides Regina Schwartz , Chaofan Chen , Joseph Y. Lo , Cynthia Rudin

In response to the COVID-19 pandemic, the integration of interpretable machine learning techniques has garnered significant attention, offering transparent and understandable insights crucial for informed clinical decision making. This…

Machine Learning · Computer Science 2024-09-10 Jinzhi Shen , Ke Ma

Existing methods, such as concept bottleneck models (CBMs), have been successful in providing concept-based interpretations for black-box deep learning models. They typically work by predicting concepts given the input and then predicting…

Computer Vision and Pattern Recognition · Computer Science 2025-01-03 Xinyue Xu , Yi Qin , Lu Mi , Hao Wang , Xiaomeng Li

The design of interpretable deep learning models working in relational domains poses an open challenge: interpretable deep learning methods, such as Concept Bottleneck Models (CBMs), are not designed to solve relational problems, while…

Machine Learning · Computer Science 2024-10-28 Pietro Barbiero , Francesco Giannini , Gabriele Ciravegna , Michelangelo Diligenti , Giuseppe Marra

Timely and accurate diagnosis of appendicitis is critical in clinical settings to prevent serious complications. While CT imaging remains the standard diagnostic tool, the growing number of cases can overwhelm radiologists, potentially…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Chia-Wen Huang , Haw Hwai , Chien-Chang Lee , Pei-Yuan Wu

Understanding model predictions is critical in healthcare, to facilitate rapid verification of model correctness and to guard against use of models that exploit confounding variables. We introduce the challenging new task of explainable…

Image and Video Processing · Electrical Eng. & Systems 2022-08-23 Rachel Lea Draelos , Lawrence Carin

Machine learning models for radiology benefit from large-scale data sets with high quality labels for abnormalities. We curated and analyzed a chest computed tomography (CT) data set of 36,316 volumes from 19,993 unique patients. This is…

Image and Video Processing · Electrical Eng. & Systems 2020-10-14 Rachel Lea Draelos , David Dov , Maciej A. Mazurowski , Joseph Y. Lo , Ricardo Henao , Geoffrey D. Rubin , Lawrence Carin