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Concept Bottleneck Models (CBMs) are regarded as inherently interpretable because they first predict a set of human-defined concepts which are used to predict a task label. For inherent interpretability to be fully realised, and ensure…

Concept Bottleneck Models (CBMs) assume that training examples (e.g., x-ray images) are annotated with high-level concepts (e.g., types of abnormalities), and perform classification by first predicting the concepts, followed by predicting…

Large, publicly available clinical datasets have emerged as a novel resource for understanding disease heterogeneity and to explore personalization of therapy. These datasets are derived from data not originally collected for research…

Interpretable models are designed to make decisions in a human-interpretable manner. Representatively, Concept Bottleneck Models (CBM) follow a two-step process of concept prediction and class prediction based on the predicted concepts. CBM…

Deep learning has advanced medical image classification, but interpretability challenges hinder its clinical adoption. This study enhances interpretability in Chest X-ray (CXR) classification by using concept bottleneck models (CBMs) and a…

Acute appendicitis characterized by a painful inflammation of the vermiform appendix is one of the most common surgical emergencies. Localizing the appendix is challenging due to its unclear anatomy amidst the complex colon-structure as…

Deep learning representations are often difficult to interpret, which can hinder their deployment in sensitive applications. Concept Bottleneck Models (CBMs) have emerged as a promising approach to mitigate this issue by learning…

Machine learning methods have shown large potential for the automatic early diagnosis of Alzheimer's Disease (AD). However, some machine learning methods based on imaging data have poor interpretability because it is usually unclear how…

The main challenges hindering the adoption of deep learning-based systems in clinical settings are the scarcity of annotated data and the lack of interpretability and trust in these systems. Concept Bottleneck Models (CBMs) offer inherent…

Despite their success, Large-Language Models (LLMs) still face criticism due to their lack of interpretability. Traditional post-hoc interpretation methods, based on attention and gradient-based analysis, offer limited insights as they only…

Concept bottleneck models (CBM) aim to improve model interpretability by predicting human level "concepts" in a bottleneck within a deep learning model architecture. However, how the predicted concepts are used in predicting the target…

Background: Cirrhosis is a progressive liver disease with high mortality and frequent complications, notably acute kidney injury (AKI), which occurs in up to 50% of hospitalized patients and worsens outcomes. AKI stems from complex…

Deep learning methods based on Convolutional Neural Networks (CNNs) have shown great potential to improve early and accurate diagnosis of Alzheimer's disease (AD) dementia based on imaging data. However, these methods have yet to be widely…

Concept Bottleneck Models (CBMs) aim for ante-hoc interpretability by learning a bottleneck layer that predicts interpretable concepts before the decision. State-of-the-art approaches typically select which concepts to learn via human…

Deep learning approaches have recently been extensively explored for the prognostics of industrial assets. However, they still suffer from a lack of interpretability, which hinders their adoption in safety-critical applications. To improve…

Concept Bottleneck Models (CBMs) offer interpretable alternatives to black-box predictors by introducing human-relatable concepts before the final output. However, existing CBMs struggle to verify whether predicted concepts correspond to…

Concept bottleneck models (CBMs) improve neural network interpretability by introducing an intermediate layer that maps human-understandable concepts to predictions. Recent work has explored the use of vision-language models (VLMs) to…

Concept Bottleneck Models (CBMs) are machine learning models that improve interpretability by grounding their predictions on human-understandable concepts, allowing for targeted interventions in their decision-making process. However, when…

There has been considerable recent interest in interpretable concept-based models such as Concept Bottleneck Models (CBMs), which first predict human-interpretable concepts and then map them to output classes. To reduce reliance on…

Deep learning models have gained increasing adoption in medical image analysis. However, these models often produce overconfident predictions, which can compromise clinical accuracy and reliability. Bridging the gap between high-performance…