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A patient-specific fluid-structure interaction (FSI) model of a phase-contrast magnetic resonance angiography (PC-MRA) imaged arteriovenous fistula is presented. The numerical model is developed and simulated using a commercial multiphysics…

Medical Physics · Physics 2018-01-30 W. P. Guess , B. D. Reddy , A. McBride , B. Spottiswoode , J. Downs , T. Franz

Numerical simulations to evaluate thoracic aortic hemodynamics include a computational fluid dynamic (CFD) approach or fluid-structure interaction (FSI) approach. While CFD neglects the arterial deformation along the cardiac cycle by…

Fluid-Structure Interaction (FSI) can be investigated by means of non-linear Finite Element Models (FEM), suitable to capture large deflections of structural parts interacting with fluids, and Computational Fluid Dynamics (CFD). High…

The zebrafish is a valuable model organism for studying cardiac development and diseases due to its many shared aspects of genetics and anatomy with humans and ease of experimental manipulations. Computational fluid-structure interaction…

Tissues and Organs · Quantitative Biology 2025-06-23 Alexander D. Kaiser , Jing Wang , Aaron L. Brown , Enbo Zhu , Tzung Hsiai , Alison L. Marsden

In this work, we present a computational fluid-structure interaction (FSI) study for a healthy patient-specific pulmonary arterial tree using the unified continuum and variational multiscale (VMS) formulation we previously developed. The…

Computational Physics · Physics 2020-08-19 Ju Liu , Weiguang Yang , Ingrid S. Lan , Alison L. Marsden

Accurate simulation of blood flow in deformable vessels is critical in cardiovascular research for understanding disease progression and informing clinical decision-making. However, due to the thin-walled nature of arteries, traditional…

Computational Engineering, Finance, and Science · Computer Science 2026-01-05 Chenxi Zhao , Dong Wu , Weiyi Kong , Oskar J. Haidn , Xiangyu Hu

We study the impact of using fluid-structure interactions (FSI) to simulate blood flow in a large stenosed artery. We compare typical flow configurations using Navier-Stokes in a rigid geometry setting to a fully coupled FSI model. The…

Computational Physics · Physics 2021-02-01 Lukas Failer , Piotr Minakowski , Thomas Richter

Cardiac fluid dynamics fundamentally involves interactions between complex blood flows and the structural deformations of the muscular heart walls and the thin, flexible valve leaflets. There has been longstanding scientific, engineering,…

Computer simulations of blood flow in patients with anomalous aortic origin of a coronary artery (AAOCA) have the promise to provide insight into this complex disease. They provide an in-silico experimental platform to explore possible…

Tissues and Organs · Quantitative Biology 2024-05-06 Charles Puelz , Craig G. Rusin , Dan Lior , Shagun Sachdeva , Tam T. Doan , Lindsay F. Eilers , Dana Reaves-O'Neal , Silvana Molossi

We present a new model and a novel loosely coupled partitioned numerical scheme modeling fluid-structure interaction (FSI) in blood flow allowing non-zero longitudinal displacement. Arterial walls are modeled by a {linearly viscoelastic,…

Numerical Analysis · Mathematics 2015-06-05 Martina Bukac , Suncica Canic , Roland Glowinski , Josip Tambaca , Annalisa Quaini

High-resolution and anatomically realistic computer models of biological soft tissues play a significant role in the understanding of the function of cardiovascular components in health and disease. However, the computational effort to…

Medical Physics · Physics 2015-08-12 Christoph M. Augustin , Gerhard A. Holzapfel , Olaf Steinbach

In our recent work, we introduced the reduced unified continuum formulation for vascular fluid-structure interaction (FSI) and demonstrated enhanced solver accuracy, scalability, and performance compared to conventional approaches. We…

Computational Physics · Physics 2022-03-03 Ingrid S. Lan , Ju Liu , Weiguang Yang , Judith Zimmermann , Daniel B. Ennis , Alison L. Marsden

Passive flow control via fluid-structure interaction (FSI) is a promising paradigm for unmanned aerial vehicles operating in vortex-dominated low Reynolds number regimes. A flexible structure has the potential to passively alter key…

Fluid Dynamics · Physics 2024-11-07 Srikumar Balasubramanian , Andres Goza

We report a novel physics-informed neural framework for reconstructing unsteady fluid-structure interactions (FSI) from sparse, single-phase observations of the flow. Our approach combines a modal surface model with coordinate neural…

Fluid Dynamics · Physics 2026-04-07 Rui Tang , Ke Zhou , Jifu Tan , Samuel J. Grauer

We implement full, three-dimensional constrained mixture theory for vascular growth and remodeling into a finite element fluid-structure interaction (FSI) solver. The resulting "fluid-solid-growth" (FSG) solver allows long term,…

Computational Engineering, Finance, and Science · Computer Science 2023-08-11 Erica L. Schwarz , Martin R. Pfaller , Jason M. Szafron , Marcos Latorre , Stephanie E. Lindsey , Christopher K. Breuer , Jay D. Humphrey , Alison L. Marsden

We propose a computational framework for vascular fluid-structure interaction (FSI), focusing on biomechanical modeling, geometric modeling, and solver technology. The biomechanical model is constructed based on the unified continuum…

Fluid Dynamics · Physics 2022-06-27 Ju Liu , Jiayi Huang , Qingshuang Lu , Yujie Sun

A fluid-structure-interaction (FSI) experiment was designed and executed with a focus on producing low-frequency (~10 Hz), high-amplitude ($\pm$3.5% of the span) fin motion. This was achieved by placing a backward facing swept fin at…

In this paper, we develop a novel phase-field model for fluid-structure interaction (FSI), that is capable to handle very large deformations as well as topology changes like contact of the solid to the domain boundary. The model is based on…

Computational Physics · Physics 2023-05-03 Dominic Mokbel , Helmut Abels , Sebastian Aland

Thoracic endovascular aortic repair (TEVAR) has developed to be the most effective treatment for aortic diseases. This study aims to evaluate the biomechanical implications of the implanted endograft after TEVAR. We present a novel…

Medical Physics · Physics 2022-01-13 Yonghui Qiao , Le Mao , Ying Ding , Ting Zhu , Kun Luo , Jianren Fan

Hemodynamics in the aorta from computational fluid dynamics (CFD) simulations can provide a comprehensive analysis of relevant cardiovascular diseases. Coupling the three-element Windkessel model with the patient-specific CFD simulation to…

Fluid Dynamics · Physics 2022-07-14 Zongze Li , Wenbin Mao
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