Related papers: A Personalized Fluid-structure Interaction Modelin…
AFSI is a novel, open-source fluid-structure interaction (FSI) solver that extends the capabilities of the FEniCS finite element library through an immersed boundary (IB) framework. Designed to simulate large deformations in hyperelastic…
This paper presents a new method for modeling the mechanics of the aortic valve, and simulates its interaction with blood. As much as possible, the model construction is based on first principles, but such that the model is consistent with…
Cardiovascular diseases are among the most important causes of global mortality. Computational Fluid Dynamics (CFD) is a powerful research tool that analyzes the hemodynamics of artery and blood flow patterns. In this study, CFD simulations…
We develop a one-dimensional model for the unsteady fluid--structure interaction (FSI) between a soft-walled microchannel and viscous fluid flow within it. A beam equation, which accounts for both transverse bending rigidity and nonlinear…
Prosthetic heart valve interventions such as TAVR have surged over the past decade, but the associated complication of long-term, life-threatening thrombotic events continues to undermine patient outcomes. Thus, improving thrombogenic risk…
Mathematical models are widely recognized as a valuable tool for cardiovascular diagnosis and the study of circulatory diseases, especially to obtain data that require otherwise invasive measurements. To correctly simulate body…
Computational fluid dynamics (CFD) is increasingly used to study blood flows in patient-specific arteries for understanding certain cardiovascular diseases. The techniques work quite well for relatively simple problems, but need…
A rigorous derivation and validation for linear fluid-structure-interaction (FSI) equations for a rigid-body-motion problem is performed in an Eulerian framework. We show that the added-stiffness terms arising in the formulation of Fanion…
Fetal growth restriction (FGR) is a prevalent pregnancy condition characterised by failure of the fetus to reach its genetically predetermined growth potential. We explore the application of model fitting techniques, linear regression…
An interface control principle is proposed for unsteady fluid-structure in- teraction (FSI) analyses. This principle introduces a method of explicitly controlling the interface motion in the temporal direction to minimize the residual force…
Phononic materials (PMs) are periodic media that exhibit novel elastodynamic responses. While PMs have made progress in vibration-mitigation applications, recent studies have demonstrated the potential of PMs to passively and adaptively…
We propose a mathematical and numerical model for the simulation of the heart function that couples cardiac electrophysiology, active and passive mechanics and hemodynamics, and includes reduced models for cardiac valves and the circulatory…
Mathematical models and numerical simulations are widely used in the field of hemodynamics, representing a valuable resource to better understand physiological and pathological processes. The theory behind the phenomenon is closely related…
Purpose: To develop a MRI acquisition and reconstruction framework for volumetric cine visualisation of the fetal heart and great vessels in the presence of maternal and fetal motion. Methods: Four-dimensional depiction was achieved using a…
Accurate 3D aortic construction is crucial for clinical diagnosis, preoperative planning, and computational fluid dynamics (CFD) simulations, as it enables the estimation of critical hemodynamic parameters such as blood flow velocity,…
The effects of the aortic geometry on its mechanics and blood flow, and subsequently on aortic pathologies, remain largely unexplored. The main obstacle lies in obtaining patient-specific aorta models, an extremely difficult procedure in…
Each year, approximately 300,000 heart valve repair or replacement procedures are performed worldwide, including approximately 70,000 aortic valve replacement surgeries in the United States alone. This paper describes progress in…
We present the development and benchmarking of an in-house fluid-structure interaction (FSI) solver. An implicit partitioned approach is utilized to couple a sharp-interface immersed boundary (IB) method based flow solver and a…
Intracardiac flow patterns are shaped by the coupled motion of the cardiac chambers and heart valves and provide important information about cardiac function. However, clinical flow imaging remains limited by exam times, noise, resolution,…
Computational fluid dynamics (CFD) studies of left atrial flows have reached a sophisticated level, e.g., revealing plausible relationships between hemodynamics and stresses with atrial fibrillation. However, little focus has been on…