Related papers: Non-line-of-sight photoacoustic imaging
Herein we report the first in-human transcranial imaging of brain function using photoacoustic computed tomography. Functional responses to benchmark motor tasks were imaged on both the skull-less and the skull-intact hemispheres of a…
Photoacoustic imaging (PAI), by combining high optical contrast with ultrasonic resolution, offers a promising noninvasive approach for dynamic monitoring of cerebral vasculature. However, transcranial PAI still faces significant challenges…
Transcranial ultrasound is more and more used for therapy and imaging of the brain. However, the skull is a highly attenuating and aberrating medium, with different structures and acoustic properties between samples and even within a…
Photoacoustic imaging combines the high contrast of optical imaging with the deep penetration depth of ultrasonic imaging, showing great potential in cerebrovascular disease detection. However, the ultrasonic wave suffers strong attenuation…
Acoustic impedance mismatches between soft tissues and bones are known to result in strong aberrations in optoacoustic and ultrasound images. Of particular importance are the severe distortions introduced by the human skull, impeding…
Photoacoustic (PA) waves are strongly distorted and attenuated in skull bone. To study these effects on PA imaging, we designed and 3D-printed tissue-mimicking phantoms of human skull. We present a comparison of results in phantom and ex…
Conventional photoacoustic imaging may suffer from the limited view and bandwidth of ultrasound transducers. A deep learning approach is proposed to handle these problems and is demonstrated both in simulations and in experiments on a…
Photoacoustic imaging has shown great promise for medical imaging, where optical energy absorption by blood haemoglobin is used as the contrast mechanism. A numerical method was developed for the in-silico assessment of the photoacoustic…
Transcranial ultrasound simulations are increasingly used to predict in situ exposure parameters for ultrasound therapies in the brain. However, there can be considerable uncertainty in estimating the acoustic medium properties of the skull…
Photoacoustic tomography (PAT) is a newly developed medical imaging modality, which combines the advantages of pure optical imaging and ultrasound imaging, owning both high optical contrast and deep penetration depth. Very recently, PAT is…
Photoacoustic imaging is an emerging technology based on the photoacoustic effect that has developed rapidly in recent years. It combines the high contrast of optical imaging and the high penetration and high resolution of acoustic imaging.…
Biomedical photoacoustic (PA) imaging is typically used to exploit absorption-based contrast in soft tissue at depths of several centimeters. When it is applied to measuring PA waves generated in the brain, the acoustic properties of the…
Photoacoustic tomography is a hybrid biomedical technology, which combines the advantages of acoustic and optical imaging. However, for the conventional image reconstruction method, the image quality is affected obviously by artifacts under…
Photoacoustic(PA) imaging is a non-destructive and non-invasive technology for visualizing minute blood vessel structures in the body using ultrasonic sensors. In PA imaging, the image quality of a single-shot image is poor, and it is…
Imaging the human brain vasculature with high spatial and temporal resolution remains challenging in the clinic today. Transcranial ultrasound is scarcely used for cerebrovascular imaging, due to low sensitivity and strong phase aberrations…
Photoacoustic fluctuation imaging, which exploits randomness in photoacoustic generation, provides enhanced images in terms of resolution and visibility, as compared to conventional photoacoustic images. While a few experimental…
Photoacoustic imaging (PAI) is a powerful imaging modality that relies on the PA effect. PAI works on the principle of electromagnetic energy absorption by the exogenous contrast agents and/or endogenous molecules present in the biological…
Ultrasound waves propagating in water or soft biological tissue are strongly reflected when encountering the skull, which limits the use of ultrasound-based techniques in transcranial imaging and therapeutic applications. Current knowledge…
Optoacoustic tomography (OAT), also known as photoacoustic tomography, is a rapidly emerging hybrid imaging technique that possesses great potential for a wide range of biomedical imaging applications. In OAT, a laser is employed to…
Noninvasive transcranial photoacoustic computed tomography (PACT) of the human brain, despite its clinical potential as a complementary technology to functional MRI, remains impeded by the acoustic distortion induced by the human skull. The…