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We introduce an innovative lumped-parameter model of the aortic valve, designed to efficiently simulate the impact of valve dynamics on blood flow. Our reduced model includes the elastic effects associated with the leaflets' curvature and…

Numerical Analysis · Mathematics 2025-04-15 Ivan Fumagalli , Luca Dede' , Alfio Quarteroni

In this paper, we present a mathematical and numerical model for blood solidification and its rupture in stenosed arteries. The interaction between the blood flow and an existing stenosis in the arterial wall is modeled as a three…

Numerical Analysis · Mathematics 2020-05-15 Fatima Abbas , Ayman Mourad

We present a two dimensional model describing the elastic behaviour of the wall of a curved blood vessel. The wall has a laminate structure consisting of several anisotropic layers of varying thickness and is assumed to be much smaller in…

Tissues and Organs · Quantitative Biology 2017-08-18 Arpan Ghosh , Vladimir Kozlov , Sergey Nazarov , David Rule

We present a new computational model for the numerical simulation of blood flow in the human left heart. To this aim, we use the Navier-Stokes equations in an Arbitrary Lagrangian Eulerian formulation to account for the endocardium motion…

Graph neural networks, recently introduced into the field of fluid flow surrogate modeling, have been successfully applied to model the temporal evolution of various fluid flow systems. Existing applications, however, are mostly restricted…

Fluid Dynamics · Physics 2026-01-14 Rui Gao , Zhi Cheng , Rajeev K. Jaiman

We propose an arbitrarily high-order accurate, fully well-balanced numerical method for the one-dimensional blood flow model. The developed method employs a continuous solution representation, combining conservative and primitive…

Numerical Analysis · Mathematics 2025-02-07 Yongle Liu , Wasilij Barsukow

Background and Objective: Hemodynamic analysis of blood flow through arteries and veins is critical for diagnosing cardiovascular diseases, such as aneurysms and stenoses, and for investigating cardiovascular parameters, such as turbulence…

Multi-component fluid flow simulations in multi-scale porous structures often involve regions that are under-resolved at practical computational resolutions. Accurately capturing the contributions from these unresolved regions is critical.…

Mathematical models of biological populations commonly use discrete structure classes to capture trait variation among individuals (e.g. age, size, phenotype, intracellular state). Upscaling these discrete models into continuum descriptions…

Populations and Evolution · Quantitative Biology 2026-03-18 Eleonora Agostinelli , Keith L. Chambers , Helen M. Byrne , Mohit P. Dalwadi

We study the flow generated by an incompressible viscoelastic fluid in a fractured porous medium. The model consists of a fluid flow governed by Stokes-Volterra equations evolving in a periodic double-porosity medium. Using the multiscale…

Analysis of PDEs · Mathematics 2014-07-30 Jean Louis Woukeng

Tumor growth beyond a critical size relies on the development of a functional vascular network, which ensures adequate oxygen and nutrient supply. In this work, we present a modeling framework based on an optimization-based 3D-1D coupling…

Numerical Analysis · Mathematics 2026-04-01 Chiara Giverso , Denise Grappein , Stefano Scialò

This study performs parameter inference in a partial differential equations system of pulmonary circulation. We use a fluid dynamics network model that takes selected parameter values and mimics the behaviour of the pulmonary haemodynamics…

Using analytical expressions for the pressure and velocity waveforms in tapered vessels, we construct a linear 1D model for wave propagation in stenotic vessels in the frequency domain. We demonstrate that using only two parameters to…

Fluid Dynamics · Physics 2019-07-24 George Papadakis , Jean Raspaud

We analyze the representation of viscous stresses in the one-fluid formulation of the two-phase Navier-Stokes equations, the model on which all computational approaches making use of a fixed mesh to discretize the flow field are grounded.…

Fluid Dynamics · Physics 2025-06-06 Jacques Magnaudet , Hadrien Bruhier , Samuel Mer , Thomas Bonometti

We analyze a diffuse interface model for multi-phase flows of $N$ incompressible, viscous Newtonian fluids with different densities. In the case of a bounded and sufficiently smooth domain existence of weak solutions in two and three space…

Analysis of PDEs · Mathematics 2024-01-15 Helmut Abels , Harald Garcke , Andrea Poiatti

A well-developed method to induce mixing on microscopic scales is to exploit flows generated by steady streaming. Steady streaming is a classical fluid dynamics phenomenon whereby a time-periodic forcing in the bulk or along a boundary is…

Fluid Dynamics · Physics 2015-12-02 Tamsin A. Spelman , Eric Lauga

Active- and transfer-learning are applied to polymer flows for the multiscale discovery of effective constitutive approximations required in viscoelastic flow simulation. The result is macroscopic rheology directly connected to a…

Computational Physics · Physics 2021-02-03 Lifei Zhao , Zhen Li , Zhicheng Wang , Bruce Caswell , Jie Ouyang , George Em Karniadakis

Flow of cerebrospinal fluid in perivascular spaces is a key mechanism underlying brain transport and clearance. In this paper, we present a mathematical and numerical formalism for reduced models of pulsatile viscous fluid flow in networks…

Fluid Dynamics · Physics 2021-11-25 Cécile Daversin-Catty , Ingeborg G. Gjerde , Marie E. Rognes

Asymptotic multi-layer analyses and computation of solutions for turbulent flows over steady and unsteady monochromatic surface wave are reviewed, in the limits of low turbulent stresses and small wave amplitude. The structure of the flow…

Fluid Dynamics · Physics 2013-12-17 S. G. Sajjadi , J. C. R. Hunt , F. Drullion

The accurate and efficient modeling of granular flows and their interactions with external bodies is an open research problem. Continuum methods can be used to capture complexities neglected by terramechanics models without the…

Soft Condensed Matter · Physics 2022-04-27 Amin Haeri , Krzysztof Skonieczny
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