Related papers: Multiscale constitutive framework of 1D blood flow…
The work analyzes a one-dimensional viscoelastic model of blood vessel growth under nonlinear friction with surroundings, and provides numerical simulations for various growing cases. For the nonlinear differential equations, two sufficient…
Morphology of cardiovascular tissue is influenced by the unsteady behavior of the blood flow and vice versa. Therefore, the pathogenesis of several cardiovascular diseases is directly affected by the blood-flow dynamics. Understanding flow…
In this study, we develop computational models and methodology for accurate multi-component-flow simulation in under-resolved multi-scale porous structures. It is generally impractical to fully resolve the flow in porous structures with…
The modeling of multi-phase flow is very challenging, given the range of scales as well as the diversity of flow regimes that one encounters in this context. We revisit the discrete equation method (DEM) for two-phase flow in the absence of…
We present a methodology for simulating three-dimensional flow of incompressible viscoplastic fluids modelled by generalised Newtonian rheological equations. It is implemented in a highly efficient framework for massively parallelisable…
Detection and monitoring of patients with pulmonary hypertension, defined as mean blood pressure in the main pulmonary artery above 25 mmHg, requires a combination of imaging and hemodynamic measurements. This study demonstrates how to…
When simulating three-dimensional flows interacting with deformable and elastic obstacles, current methods often encounter complexities in the governing equations and challenges in numerical implementation. In this work, we introduce a…
With the objective of modeling both separate and disperse two-phase flows, we use in this paper a methodology for deriving two-fluid models that do not assume any flow topology. This methodology is based on a variational principle and on…
A new framework for two-fluids flow using a Finite Element/Level Set method is presented and verified through the simulation of the rising of a bubble in a viscous fluid. This model is then enriched to deal with vesicles (which mimic red…
We study two-phase flow for Darcy and Brinkman regimes. To reduce the computational complexity for flow in vertical equilibrium various simplified models have been suggested. Examples are dimensional reduction by vertical integration, the…
The presented multi-scale, closed-loop blood circulation model includes arterial, venous, and portal venous systems, heart-pulmonary circulation, and micro-circulation in capillaries. One-dimensional models simulate large blood vessel flow,…
We introduce a new heterogeneous multi-scale method for the simulation of flows of non-Newtonian fluids in general geometries and present its application to paradigmatic two-dimensional flows of polymeric fluids. Our method combines…
Usually, clinicians assess the correct hemodynamic behavior and fetal well-being during the gestational age thanks to their professional expertise, with the support of some indices defined for Doppler fetal waveforms. Although this approach…
This work presents a unified viscoelastic-viscoplastic continuum framework for modeling rate-dependent granular flows across regimes. The formulation incorporates two distinct rate-dependent mechanisms, namely micro-inertia and viscoelastic…
We consider dry granular flow down an inclined chute with a localised contraction theoretically and numerically. The flow regimes are predicted through a novel extended one-dimensional hydraulic theory. A discrete particle method validated…
Cardiovascular modeling has rapidly advanced over the past few decades due to the rising needs for health tracking and early detection of cardiovascular diseases. While 1-D arterial models offer an attractive compromise between…
We have measured the nonlinear rheological response of a model transient network over a large range of steady shear rates. The system is built up from an oil in water droplet microemulsion into which a telechelic polymer is incorporated.…
The asymmetry model for the highly viscous flow postulates thermally activated jumps from a practically undistorted ground state to strongly distorted, but stable structures, with a pronounced Eshelby backstress from the distorted…
When a blood vessel ruptures or gets inflamed, the human body responds by rapidly forming a clot to restrict the loss of blood. Platelets aggregation at the injury site of the blood vessel occurring via platelet-platelet adhesion, tethering…
New asymptotic models are formulated to capture the thermal transfer across falling films. These models enable to simulate a wide range of Biot and Peclet number values, without displaying nonphysical behaviors. The models correctly capture…