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One of the symptoms observed in the early stages of Parkinson's Disease (PD) is speech impairment. Speech disorders can be used to detect this disease before it degenerates. This work analyzes speech features and machine learning approaches…

Audio and Speech Processing · Electrical Eng. & Systems 2021-11-22 Adedolapo Aishat Toye , Suryaprakash Kompalli

Background: Depression is a common mental disorder with societal and economic burden. Current diagnosis relies on self-reports and assessment scales, which have reliability issues. Objective approaches are needed for diagnosing depression.…

Neurons and Cognition · Quantitative Biology 2023-07-18 Sijin Cai , Nanfeng Zhang , Jiaying Zhu , Yanjie Liu , Yongjin Zhou

Deep learning models are rapidly gaining interest for real-world applications in behavioral health. An important gap in current literature is how well such models generalize over different populations. We study Natural Language Processing…

Computation and Language · Computer Science 2024-12-30 Tomek Rutowski , Elizabeth Shriberg , Amir Harati , Yang Lu , Ricardo Oliveira , Piotr Chlebek

Depression is a critical concern in global mental health, prompting extensive research into AI-based detection methods. Among various AI technologies, Large Language Models (LLMs) stand out for their versatility in mental healthcare…

Audio and Speech Processing · Electrical Eng. & Systems 2024-09-25 Xiangyu Zhang , Hexin Liu , Kaishuai Xu , Qiquan Zhang , Daijiao Liu , Beena Ahmed , Julien Epps

Depression is characterized by persistent sadness and loss of interest, significantly impairing daily functioning and now a widespread mental disorder. Traditional diagnostic methods rely on subjective assessments, necessitating objective…

Using Instagram data from 166 individuals, we applied machine learning tools to successfully identify markers of depression. Statistical features were computationally extracted from 43,950 participant Instagram photos, using color analysis,…

Social and Information Networks · Computer Science 2016-08-16 Andrew G. Reece , Christopher M. Danforth

Speech-based automatic detection of Alzheimer's disease (AD) and depression has attracted increased attention. Confidence estimation is crucial for a trust-worthy automatic diagnostic system which informs the clinician about the confidence…

Computation and Language · Computer Science 2024-09-10 Wen Wu , Chao Zhang , Philip C. Woodland

Automated detection of voice disorders with computational methods is a recent research area in the medical domain since it requires a rigorous endoscopy for the accurate diagnosis. Efficient screening methods are required for the diagnosis…

Quantitative Methods · Quantitative Biology 2018-12-06 Vibhuti Gupta

With the global population aging rapidly, Alzheimer's disease (AD) is particularly prominent in older adults, which has an insidious onset and leads to a gradual, irreversible deterioration in cognitive domains (memory, communication,…

Audio and Speech Processing · Electrical Eng. & Systems 2023-03-15 Jinchao Li , Kaitao Song , Junan Li , Bo Zheng , Dongsheng Li , Xixin Wu , Xunying Liu , Helen Meng

This study investigates whether speech-based depression detection models learn depression-related acoustic biomarkers or instead rely on speaker identity cues. Using the DAIC-WOZ dataset, we propose a data-splitting strategy that controls…

Audio and Speech Processing · Electrical Eng. & Systems 2026-04-17 Hsiang-Chen Yeh , Luqi Sun , Aurosweta Mahapatra , Shreeram Suresh Chandra , Emily Mower Provost , Berrak Sisman

Existing depression screening predominantly relies on standardized questionnaires (e.g., PHQ-9, BDI), which suffer from high misdiagnosis rates (18-34% in clinical studies) due to their static, symptom-counting nature and susceptibility to…

Neurons and Cognition · Quantitative Biology 2025-04-24 Zhenguang Zhong , Zhixuan Wang

Automatic depression detection from doctor-patient conversations has gained momentum thanks to the availability of public corpora and advances in language modeling. However, interpretability remains limited: strong performance is often…

Increasingly frequent publications in the literature report voice quality differences between depressed patients and controls. Here, we examine the possibility of using voice analysis as an early warning signal for the development of…

Sound · Computer Science 2024-11-19 Klaus R. Scherer , Felix Burkhardt , Uwe D. Reichel , Florian Eyben , Björn W. Schuller

Background: Captured between clinical appointments using mobile devices, spoken language has potential for objective, more regular assessment of symptom severity and earlier detection of relapse in major depressive disorder. However,…

Major Depressive Disorder (MDD) is a highly prevalent mental health condition, and a deeper understanding of its neurocognitive foundations is essential for identifying how core functions such as emotional and self-referential processing…

Preliminary detection of mild depression could immensely help in effective treatment of the common mental health disorder. Due to the lack of proper awareness and the ample mix of stigmas and misconceptions present within the society,…

Model interpretability has become important to engenders appropriate user trust by providing the insight into the model prediction. However, most of the existing machine learning methods provide no interpretability for depression…

Information Retrieval · Computer Science 2021-04-29 Hamad Zogan , Imran Razzak , Xianzhi Wang , Shoaib Jameel , Guandong Xu

Respiratory diseases are among the most common causes of severe illness and death worldwide. Prevention and early diagnosis are essential to limit or even reverse the trend that characterizes the diffusion of such diseases. In this regard,…

Audio and Speech Processing · Electrical Eng. & Systems 2019-07-15 Diego Perna , Andrea Tagarelli

Speech patterns have been identified as potential diagnostic markers for neuropsychiatric conditions. However, most studies only compare a single clinical group to healthy controls, whereas clinical practice often requires differentiating…

Accurate and interpretable predictions of depression severity are essential for clinical decision support, yet existing models often lack uncertainty estimates and temporal modeling. We propose PTTSD, a Probabilistic Textual Time Series…

Computation and Language · Computer Science 2025-11-07 Fabian Schmidt , Seyedehmoniba Ravan , Vladimir Vlassov