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We show that with spatially incoherent illumination, the point spread function width of an imaging interferometer like that used in full-field optical coherence tomography (FFOCT) is almost insensitive to aberrations that mostly induce a…

Optics · Physics 2016-08-16 Peng Xiao , Mathias Fink , A. Claude Boccara

We suggest a new multimodal imaging technique for quantitatively measuring the integral (thickness-average) refractive index of the nuclei of live biological cells in suspension. For this aim, we combined quantitative phase microscopy with…

Image super-resolution (SR) has attracted increasing attention due to its wide applications. However, current SR methods generally suffer from over-smoothing and artifacts, and most work only with fixed magnifications. This paper introduces…

Computer Vision and Pattern Recognition · Computer Science 2023-09-06 Sicheng Gao , Xuhui Liu , Bohan Zeng , Sheng Xu , Yanjing Li , Xiaoyan Luo , Jianzhuang Liu , Xiantong Zhen , Baochang Zhang

Fluorescence molecular tomography (FMT) is a sensitive optical imaging technology widely used in biomedical research. However, the ill-posedness of the inverse problem poses a huge challenge to FMT reconstruction. Although end-to-end deep…

Image and Video Processing · Electrical Eng. & Systems 2025-03-18 Peng Zhang , Qianqian Xue , Xingyu Liu , Guanglei Zhang , Wenjian Wang , Jiye Liang

Incoherent Diffraction Imaging - IDI - is a diffraction-based imaging technique that has been recently proposed to exploit the partial coherence of incoherently scattered light to retrieve structural information from the scattering centers.…

Molecular dipoles near interfaces emit highly directional radiation due to near-field interactions, making surface-bound fluorophores sensitive probes of local physicochemical changes. We introduce smart coverslips, stably coated with…

Imaging airway tissue, optical coherence tomography (OCT) provides cross-sectional images of tissue structures, shows cilia movement and mucus secretion, but does not provide sufficient contrast to differentiate individual cells. By using…

This work proposes DOFS, a pilot dataset of 3D deformable objects (DOs) (e.g., elasto-plastic objects) with full spatial information (i.e., top, side, and bottom information) using a novel and low-cost data collection platform with a…

Computer Vision and Pattern Recognition · Computer Science 2024-10-30 Zhen Zhang , Xiangyu Chu , Yunxi Tang , K. W. Samuel Au

Diffraction tomography (DT) has been widely explored in transmission-mode configurations, enabling high-resolution, label-free 3D imaging. However, industrial metrology applications, such as semiconductor inspection, typically involve…

Optics · Physics 2026-02-04 Jiabei Zhu , Tongyu Li , Hao Wang , Yi Shen , Guorong Hu , Lei Tian

The mechanical properties of human soft tissue are crucial for impact biomechanics, rehabilitation engineering and surgical simulation. Validation of these constitutive models using human data remains challenging and often requires the use…

Medical Physics · Physics 2016-04-25 Kevin M. Moerman , Cathy A. Holt , Sam L. Evans , Ciaran K. Simms

Reflective ptychography is a promising lensless imaging technique with a wide field of view, offering significant potential for applications in semiconductor manufacturing and detection. However, many semiconductor materials are coated with…

Optics · Physics 2025-01-03 Yun Gao , Qijun You , Peixiang Lu , Wei Cao

We demonstrate a three-dimensional (3D) optical diffraction tomographic technique with optimal frequency combination (OFC-ODT) for the 3D quantitative phase imaging of unlabeled specimens. Three sets of through-focus intensity images are…

Optics · Physics 2018-03-06 Jiaji Li , Qian Chen Jiasong Sun , Jialin Zhang , Junyi Ding , Chao Zuo

High-fidelity 3D tooth models are essential for digital dentistry, but must capture both the detailed crown and the complete root. Clinical imaging modalities are limited: Cone-Beam Computed Tomography (CBCT) captures the root but has a…

Image and Video Processing · Electrical Eng. & Systems 2026-01-23 Yi Zhu , Razmig Kechichian , Raphaël Richert , Satoshi Ikehata , Sébastien Valette

Computed tomography (CT) is a cornerstone imaging modality for non-invasive, high-resolution visualization of internal anatomical structures. However, when the scanned object exceeds the scanner's field of view (FOV), projection data are…

Image and Video Processing · Electrical Eng. & Systems 2026-04-09 Zhenhao Li , Song Ni , Long Yang , Xiaojie Yin , Haijun Yu , Jiazhou Wang , Hongbin Han , Weigang Hu , Yixing Huang

We present a computational method for full-range interferometric synthetic aperture microscopy (ISAM) under dispersion encoding. With this, one can effectively double the depth range of optical coherence tomography (OCT), whilst…

Image and Video Processing · Electrical Eng. & Systems 2020-02-03 Jonathan H. Mason , Mike E. Davies , Pierre O. Bagnaninchi

During In Vitro Fertilisation (IVF), combining time-lapse contrast microscopy with suitable image processing techniques could facilitate non-invasive classification of oocyte health, driving oocyte selection to maximise success rates. One…

Optical coherence tomography (OCT) is a powerful and noninvasive method for retinal imaging. In this paper, we introduce a fast segmentation method based on a new variant of spectral graph theory named diffusion maps. The research is…

Computer Vision and Pattern Recognition · Computer Science 2012-10-09 Raheleh Kafieh , Hossein Rabbani , Michael D. Abramoff , Milan Sonka

Though structured illumination (SI) microscopy is a popular imaging technique conventionally associated with fluorescent super-resolution, recent works have suggested its applicability towards sub-diffraction coherent imaging with…

Quantitative Methods · Quantitative Biology 2024-12-13 Shwetadwip Chowdhury , Will J. Eldridge , Adam Wax , Joseph A. Izatt

We present a benchmark pilot study in which high-resolution Full-Field Optical Coherence Tomography (FF-OCT) is used to image human breast tissue and is evaluated to assess its ability to aid the pathologist's management of intra-operative…

Multi-frame high dynamic range (HDR) imaging aims to reconstruct ghost-free images with photo-realistic details from content-complementary but spatially misaligned low dynamic range (LDR) images. Existing HDR algorithms are prone to…

Computer Vision and Pattern Recognition · Computer Science 2023-10-10 Hailing Wang , Wei Li , Yuanyuan Xi , Jie Hu , Hanting Chen , Longyu Li , Yunhe Wang