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Federated learning (FL) aims to collaboratively train a shared model across multiple clients without transmitting their local data. Data heterogeneity is a critical challenge in realistic FL settings, as it causes significant performance…

Machine Learning · Computer Science 2023-11-15 Yuwei Wang , Runhan Li , Hao Tan , Xuefeng Jiang , Sheng Sun , Min Liu , Bo Gao , Zhiyuan Wu

Federated learning has emerged as a promising, massively distributed way to train a joint deep model over large amounts of edge devices while keeping private user data strictly on device. In this work, motivated from ensuring fairness among…

Machine Learning · Computer Science 2023-01-25 Zeou Hu , Kiarash Shaloudegi , Guojun Zhang , Yaoliang Yu

There is a growing interest in applying machine learning techniques to healthcare. Recently, federated learning (FL) is gaining popularity since it allows researchers to train powerful models without compromising data privacy and security.…

Machine Learning · Computer Science 2022-05-23 Wang Lu , Jindong Wang , Yiqiang Chen , Xin Qin , Renjun Xu , Dimitrios Dimitriadis , Tao Qin

Pharmaceutical industry can better leverage its data assets to virtualize drug discovery through a collaborative machine learning platform. On the other hand, there are non-negligible risks stemming from the unintended leakage of…

Cryptography and Security · Computer Science 2022-06-10 Balazs Pejo , Mina Remeli , Adam Arany , Mathieu Galtier , Gergely Acs

The proliferation of edge devices has brought Federated Learning (FL) to the forefront as a promising paradigm for decentralized and collaborative model training while preserving the privacy of clients' data. However, FL struggles with a…

Machine Learning · Computer Science 2024-05-14 Mahdi Morafah , Matthias Reisser , Bill Lin , Christos Louizos

Federated learning (FL) typically faces data heterogeneity, i.e., distribution shifting among clients. Sharing clients' information has shown great potentiality in mitigating data heterogeneity, yet incurs a dilemma in preserving privacy…

Machine Learning · Computer Science 2023-10-12 Zhiqin Yang , Yonggang Zhang , Yu Zheng , Xinmei Tian , Hao Peng , Tongliang Liu , Bo Han

Federated Learning (FL) has emerged as an effective learning paradigm for distributed computation owing to its strong potential in capturing underlying data statistics while preserving data privacy. However, in cases of practical data…

Machine Learning · Computer Science 2023-05-22 Achintha Wijesinghe , Songyang Zhang , Zhi Ding

Interaction between pharmacological agents can trigger unexpected adverse events. Capturing richer and more comprehensive information about drug-drug interactions (DDI) is one of the key tasks in public health and drug development.…

Machine Learning · Computer Science 2020-10-19 Yuanfei Dai , Chenhao Guo , Wenzhong Guo , Carsten Eickhoff

Federated Learning (FL) facilitates collaborative learning among multiple clients in a distributed manner and ensures the security of privacy. However, its performance inevitably degrades with non-Independent and Identically Distributed…

Machine Learning · Computer Science 2024-12-09 Yunlu Yan , Huazhu Fu , Yuexiang Li , Jinheng Xie , Jun Ma , Guang Yang , Lei Zhu

Federated Learning (FL) is a novel distributed machine learning approach to leverage data from Internet of Things (IoT) devices while maintaining data privacy. However, the current FL algorithms face the challenges of non-independent and…

Machine Learning · Computer Science 2023-12-20 Gang Hu , Yinglei Teng , Nan Wang , F. Richard Yu

Federated learning leverages data across institutions to improve clinical discovery while complying with data-sharing restrictions and protecting patient privacy. This paper provides a gentle introduction to this approach in bioinformatics,…

The Web is naturally heterogeneous with user devices, geographic regions, browsing patterns, and contexts all leading to highly diverse, unique datasets. Federated Learning (FL) is an important paradigm for the Web because it enables…

Machine Learning · Computer Science 2026-02-05 Abdulrahman Alotaibi , Irene Tenison , Miriam Kim , Isaac Lee , Lalana Kagal

Drug-target interaction (DTI) prediction, which aims at predicting whether a drug will be bounded to a target, have received wide attention recently, with the goal to automate and accelerate the costly process of drug design. Most of the…

Biomolecules · Quantitative Biology 2023-06-27 Shengming Zhang , Yizhou Sun

Federated learning enables resource-constrained edge compute devices, such as mobile phones and IoT devices, to learn a shared model for prediction, while keeping the training data local. This decentralized approach to train models provides…

Machine Learning · Computer Science 2022-07-22 Yue Zhao , Meng Li , Liangzhen Lai , Naveen Suda , Damon Civin , Vikas Chandra

With the rapid development of computer software and hardware technologies, more and more healthcare data are becoming readily available from clinical institutions, patients, insurance companies and pharmaceutical industries, among others.…

Machine Learning · Computer Science 2020-08-24 Jie Xu , Benjamin S. Glicksberg , Chang Su , Peter Walker , Jiang Bian , Fei Wang

In the medical field, multi-center collaborations are often sought to yield more generalizable findings by leveraging the heterogeneity of patient and clinical data. However, recent privacy regulations hinder the possibility to share data,…

Machine learning in medical research, by nature, needs careful attention on obeying the regulations of data privacy, making it difficult to train a machine learning model over gathered data from different medical centers. Failure of…

Machine Learning · Computer Science 2021-10-19 Jun Luo , Shandong Wu

As one kind of distributed machine learning technique, federated learning enables multiple clients to build a model across decentralized data collaboratively without explicitly aggregating the data. Due to its ability to break data silos,…

Cryptography and Security · Computer Science 2023-06-07 Junchuan Lianga , Rong Wang , Chaosheng Feng , Chin-Chen Chang

Drug-target interaction (DTI) prediction is of great significance for drug discovery and drug repurposing. With the accumulation of a large volume of valuable data, data-driven methods have been increasingly harnessed to predict DTIs,…

Machine Learning · Computer Science 2025-11-11 Yuhao Zhang , Qinghong Guo , Qixian Chen , Liuwei Zhang , Hongyan Cui , Xiyi Chen

Federated learning (FL) was proposed to facilitate the training of models in a distributed environment. It supports the protection of (local) data privacy and uses local resources for model training. Until now, the majority of research has…