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Related papers: A Federated Learning Benchmark for Drug-Target Int…

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Drug-Target binding Affinity (DTA) prediction is essential for drug discovery. Despite the application of deep learning methods to DTA prediction, the achieved accuracy remain suboptimal. In this work, inspired by the recent success of…

Biomolecules · Quantitative Biology 2024-07-23 Qizhi Pei , Lijun Wu , Zhenyu He , Jinhua Zhu , Yingce Xia , Shufang Xie , Rui Yan

Federated Learning(FL) is popular as a privacy-preserving machine learning paradigm for generating a single model on decentralized data. However, statistical heterogeneity poses a significant challenge for FL. As a subfield of FL,…

Machine Learning · Computer Science 2024-10-22 Keting Yin , Jiayi Mao

Federated learning (FL) is a paradigm where many clients collaboratively train a model under the coordination of a central server, while keeping the training data locally stored. However, heterogeneous data distributions over different…

Machine Learning · Computer Science 2022-05-27 Yaqi Sun , Shijing Si , Jianzong Wang , Yuhan Dong , Zhitao Zhu , Jing Xiao

Recent progress in deep learning is revolutionizing the healthcare domain including providing solutions to medication recommendations, especially recommending medication combination for patients with complex health conditions. Existing…

Artificial Intelligence · Computer Science 2019-03-08 Junyuan Shang , Cao Xiao , Tengfei Ma , Hongyan Li , Jimeng Sun

This paper studies Federated Learning (FL) for binary classification of volatile financial market trends. Using a shared Long Short-Term Memory (LSTM) classifier, we compare three scenarios: (i) a centralized model trained on the union of…

Machine Learning · Computer Science 2025-09-23 Manuel Noseda , Alberto De Luca , Lukas Von Briel , Nathan Lacour

Drug discovery remains a slow and expensive process that involves many steps, from detecting the target structure to obtaining approval from the Food and Drug Administration (FDA), and is often riddled with safety concerns. Accurate…

Quantitative Methods · Quantitative Biology 2025-08-22 Ali Vefghi , Zahed Rahmati , Mohammad Akbari

Accurate prediction of drug-target interactions (DTI) is crucial for drug discovery. Recently, deep learning (DL) models for show promising performance for DTI prediction. However, these models can be difficult to use for both computer…

Machine Learning · Computer Science 2020-12-11 Kexin Huang , Tianfan Fu , Lucas Glass , Marinka Zitnik , Cao Xiao , Jimeng Sun

Federated Learning presents a way to revolutionize AI applications by eliminating the necessity for data sharing. Yet, research has shown that information can still be extracted during training, making additional privacy-preserving measures…

Machine Learning · Computer Science 2024-10-29 Beatrice Balbierer , Lukas Heinlein , Domenique Zipperling , Niklas Kühl

Federated Learning (FL) is a decentralized machine learning protocol that allows a set of participating agents to collaboratively train a model without sharing their data. This makes FL particularly suitable for settings where data privacy…

Machine Learning · Computer Science 2020-10-30 Mustafa Safa Ozdayi , Murat Kantarcioglu , Rishabh Iyer

Privacy protection is an ethical issue with broad concern in Artificial Intelligence (AI). Federated learning is a new machine learning paradigm to learn a shared model across users or organisations without direct access to the data. It has…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-08-25 Guodong Long , Tao Shen , Yue Tan , Leah Gerrard , Allison Clarke , Jing Jiang

Developing AI tools that preserve fairness is of critical importance, specifically in high-stakes applications such as those in healthcare. However, health AI models' overall prediction performance is often prioritized over the possible…

Machine Learning · Computer Science 2023-05-22 Raphael Poulain , Mirza Farhan Bin Tarek , Rahmatollah Beheshti

Federated learning is a distributed form of machine learning where both the training data and model training are decentralized. In this paper, we use federated learning in a commercial, global-scale setting to train, evaluate and deploy a…

Machine Learning · Computer Science 2018-12-10 Timothy Yang , Galen Andrew , Hubert Eichner , Haicheng Sun , Wei Li , Nicholas Kong , Daniel Ramage , Françoise Beaufays

Federated Learning (FL) is a distributed machine learning technique that allows model training among multiple devices or organizations by sharing training parameters instead of raw data. However, adversaries can still infer individual…

Machine Learning · Computer Science 2024-05-27 Xinpeng Ling , Jie Fu , Kuncan Wang , Haitao Liu , Zhili Chen

Data privacy has become a major concern in healthcare due to the increasing digitization of medical records and data-driven medical research. Protecting sensitive patient information from breaches and unauthorized access is critical, as…

Research in the food domain is at times limited due to data sharing obstacles, such as data ownership, privacy requirements, and regulations. While important, these obstacles can restrict data-driven methods such as machine learning.…

Machine Learning · Computer Science 2025-08-12 Zuzanna Fendor , Bas H. M. van der Velden , Xinxin Wang , Andrea Jr. Carnoli , Osman Mutlu , Ali Hürriyetoğlu

Federated learning (FL) is a privacy-promoting framework that enables potentially large number of clients to collaboratively train machine learning models. In a FL system, a server coordinates the collaboration by collecting and aggregating…

Machine Learning · Computer Science 2023-04-21 Huancheng Chen , Haris Vikalo

Federated learning is an emerging technique for training models from decentralized data sets. In many applications, data owners participating in the federated learning system hold not only the data but also a set of domain knowledge. Such…

Machine Learning · Computer Science 2022-08-17 Zhenan Fan , Zirui Zhou , Jian Pei , Michael P. Friedlander , Jiajie Hu , Chengliang Li , Yong Zhang

Federated Learning (FL) enables collaborative training across multiple clients while preserving data privacy, yet it struggles with data heterogeneity, where clients' data are not distributed independently and identically (non-IID). This…

Machine Learning · Computer Science 2025-12-16 Incheol Baek , Hyungbin Kim , Minseo Kim , Yon Dohn Chung

Federated learning (FL) is increasingly being recognized as a key approach to overcoming the data silos that so frequently obstruct the training and deployment of machine-learning models in clinical settings. This work contributes to a…

Machine Learning · Computer Science 2024-07-08 Fatemeh Tavakoli , D. B. Emerson , Sana Ayromlou , John Jewell , Amrit Krishnan , Yuchong Zhang , Amol Verma , Fahad Razak

Neural interfaces offer a pathway to intuitive, high-bandwidth interaction, but the sensitive nature of neural data creates significant privacy hurdles for large-scale model training. Federated learning (FL) has emerged as a promising…

Machine Learning · Computer Science 2026-02-26 Kai Malcolm , César Uribe , Momona Yamagami
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