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Dynamic Treatment Regimes (DTRs) provide a systematic framework for optimizing sequential decision-making in chronic disease management, where therapies must adapt to patients' evolving clinical profiles. Inverse probability weighting (IPW)…
Automated vulnerability detection research has made substantial progress, yet its real-world impact remains limited. Prior work found that current vulnerability datasets suffer from issues including label inaccuracy rates of 20%-71%,…
Randomized controlled trials (RCTs) are the standard for evaluating the effectiveness of clinical interventions. To address the limitations of RCTs on real-world populations, we developed a methodology that uses a large observational…
Massive electronic health records (EHRs) enable the success of learning accurate patient representations to support various predictive health applications. In contrast, doctor representation was not well studied despite that doctors play…
Repetitive laboratory testing unlikely to yield clinically useful information is a common practice that burdens patients and increases healthcare costs. Education and feedback interventions have limited success, while general test ordering…
The rapid evolution of Cyber-Physical Systems (CPS) across various domains like mobility systems, networked control systems, sustainable manufacturing, smart power grids, and the Internet of Things necessitates innovative solutions that…
Recent transfer learning (TL) approaches in industrial intelligent fault diagnosis (FD) mostly follow the "pre-train and fine-tuning" paradigm to address data drift, which emerges from variable working conditions. However, we find that this…
Standardisation of healthcare has been the focus of hospital management and clinicians since the 1990's. Electronic health records were already intended to provide clinicians with real-time access to clinical knowledge and care plans while…
Objective: To (1) demonstrate the implementation of a data science platform built on open-source technology within a large, academic healthcare system and (2) describe two computational healthcare applications built on such a platform.…
Clinical decision support systems (CDSS) augmented with artificial intelligence (AI) models are emerging as potentially valuable tools in healthcare. Despite their promise, the development and implementation of these systems typically…
Collaboration across institutional boundaries is widespread and increasing today. It depends on federations sharing data that often have governance rules or external regulations restricting their use. However, the handling of data…
Data privacy is a critical challenge in modern medical workflows as the adoption of electronic patient records has grown rapidly. Stringent data protection regulations limit access to clinical records for training and integrating machine…
Evidence derived from large-scale real-world data (RWD) is increasingly informing regulatory evaluation and healthcare decision-making. Administrative claims provide population-scale, longitudinal records of healthcare utilization,…
Analyzing model performance in various unseen environments is a critical research problem in the machine learning community. To study this problem, it is important to construct a testbed with out-of-distribution test sets that have broad…
Due to growing population and technological advances, global electricity consumption, and consequently also CO2 emissions are increasing. The residential sector makes up 25% of global electricity consumption and has great potential to…
Objective: To create a commons for infectious disease (ID) epidemiology in which epidemiologists, public health officers, data producers, and software developers can not only share data and software, but receive assistance in improving…
Like medicine, psychology, or education, data science is fundamentally an applied discipline, with most students who receive advanced degrees in the field going on to work on practical problems. Unlike these disciplines, however, data…
To curate a high-quality dataset, identifying data variance between the internal and external sources is a fundamental and crucial step. However, methods to detect shift or variance in data have not been significantly researched. Challenges…
We present a practical guide for the analysis of regression discontinuity (RD) designs in biomedical contexts. We begin by introducing key concepts, assumptions, and estimands within both the continuity-based framework and the local…
Object detectors have achieved remarkable performance in many applications; however, these deep learning models are typically designed under the i.i.d. assumption, meaning they are trained and evaluated on data sampled from the same…