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Real-world data (RWD) and real-world evidence (RWE) have been increasingly used in medical product development and regulatory decision-making, especially for rare diseases. After outlining the challenges and possible strategies to address…

Data Warehouse (DW) is an essential part of Business Intelligence. DW emerged as a fast growing reporting and analysis technique in early 1980s. Today, it has almost replaced relational databases. However, with passage of time, static and…

Databases · Computer Science 2013-10-22 Syed Ijaz Ahmad Bukhari

While randomized controlled trials (RCTs) are the gold-standard for establishing the efficacy and safety of a medical treatment, real-world evidence (RWE) generated from real-world data (RWD) has been vital in post-approval monitoring and…

Centralized electronic health record repositories are critical for advancing disease surveillance, public health research, and evidence-based policymaking. However, developing countries face persistent challenges in achieving this due to…

The approaches by which the machine learning and clinical research communities utilize real world data (RWD), including data captured in the electronic health record (EHR), vary dramatically. While clinical researchers cautiously use RWD…

The data warehouse (DW) technology was developed to integrate heterogeneous information sources for analysis purposes. Information sources are more and more autonomous and they often change their content due to perpetual transactions (data…

Databases · Computer Science 2010-12-21 wided oueslati , jalel akaichi

The explosive growth in the development of Traditional Chinese Medicine (TCM) has resulted in the continued increase in clinical and research data. The lack of standardised terminology, flaws in data quality planning and management of TCM…

Computers and Society · Computer Science 2016-06-09 Wing-Kit Sunny Lam , Tony Sahama , Randike Gajanayake

In recent years, precision agriculture is becoming very popular. The introduction of modern information and communication technologies for collecting and processing Agricultural data revolutionise the agriculture practises. This has started…

Databases · Computer Science 2021-04-13 V. M. Ngo , N. A. Le-Khac , M. T. Kechadi

The emergence of clinical data warehouses (CDWs), which contain the medical data of millions of patients, has paved the way for vast data sharing for research. The quality of MRIs gathered in CDWs differs greatly from what is observed in…

Image and Video Processing · Electrical Eng. & Systems 2024-06-19 Sophie Loizillon , Simona Bottani , Stéphane Mabille , Yannick Jacob , Aurélien Maire , Sebastian Ströer , Didier Dormont , Olivier Colliot , Ninon Burgos

Background. Clinical data warehouses (CDWs) are essential in the reuse of hospital data in observational studies or predictive modeling. However, state of-the-art CDW systems present two drawbacks. First, they do not support the management…

Quantitative Methods · Quantitative Biology 2024-09-06 Maxime Wack , Adrien Coulet , Anita Burgun , Bastien Rance

The recent implementation of the Electronic Health Record (EHR) in France is part of a more general process of digitizing information flows, as the world enters the fourth industrial revolution in a phenomenon known as Industry 4.0. Behind…

Computers and Society · Computer Science 2019-07-26 Sarah Manard , Nicolas Vergos , Simon Tamayo , Frédéric Fontane

This manuscript explores linking real-world patient data with external death data in the context of research Clinical Data Warehouses (r-CDWs). We specifically present the linking of Electronic Health Records (EHR) data for Stanford Health…

Databases · Computer Science 2022-11-04 Alvaro Andres Alvarez Peralta , Priya Desai , Somalee Datta

Increasing emphasis on the use of real-world evidence (RWE) to support clinical policy and regulatory decision-making has led to a proliferation of guidance, advice, and frameworks from regulatory agencies, academia, professional societies,…

Drug repurposing is an effective strategy to identify new uses for existing drugs, providing the quickest possible transition from bench to bedside. Existing methods for drug repurposing that mainly focus on pre-clinical information may…

Applications · Statistics 2021-04-14 Ruoqi Liu , Lai Wei , Ping Zhang

Cloud data warehouses (CDWs) bring large-scale data and compute power closer to users in enterprises. However, existing tools for analyzing data in CDWs are either limited in ad-hoc transformations or difficult to use for business users.…

Databases · Computer Science 2022-08-19 James Gale , Max Seiden , Deepanshu Utkarsh , Jason Frantz , Rob Woollen , Çağatay Demiralp

The university management is perpetually in the process of innovating policies to improve the quality of service. Intellectual growth of the students, the popularity of university are some of the major areas that management strives to…

Databases · Computer Science 2022-09-05 Anupam Khan , Sourav Ghosh , Soumya K. Ghosh

The US Food and Drug Administration (FDA) has been actively promoting the use of real-world data (RWD) in drug development. RWD can generate important real-world evidence reflecting the real-world clinical environment where the treatments…

Computers and Society · Computer Science 2021-02-03 Zhaoyi Chen , Xiong Liu , William Hogan , Elizabeth Shenkman , Jiang Bian

The integration of real-world data (RWD) and randomized controlled trials (RCT) is increasingly important for advancing causal inference in scientific research. This combination holds great promise for enhancing the efficiency of causal…

Methodology · Statistics 2024-07-02 Xi Lin , Jens Magelund Tarp , Robin J. Evans

This paper presents architecture for health care data warehouse specific to cancer diseases which could be used by executive managers, doctors, physicians and other health professionals to support the healthcare process. The data today…

Databases · Computer Science 2012-11-20 Osama El-Sayed Sheta , Ahmed Nour Eldeen

Long-horizon clinical simulation -- predicting how a patient's physiology evolves over years under specified interventions -- is central to chronic-disease care, yet existing electronic health record (EHR) models are predominantly…

Machine Learning · Computer Science 2026-05-22 Jiangyuan Wang , Xuyong Chen , Junwei He , Xu Xu , Shasha Xie , Fuman Han
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