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Polarized light microscopy provides high contrast to birefringent specimen and is widely used as a diagnostic tool in pathology. However, polarization microscopy systems typically operate by analyzing images collected from two or more light…

Optical diffraction tomography is an indispensable tool for studying objects in three-dimensions due to its ability to accurately reconstruct scattering objects. Until now this technique has been limited to coherent light because spatial…

The glow of a starry night sky, the smell of a freshly brewed cup of coffee or the sound of ocean waves breaking on the beach are representations of the physical world that have been created by the dynamic interactions of thousands of…

Neurons and Cognition · Quantitative Biology 2011-07-28 Henry Lütcke , Fritjof Helmchen

A central issue in neural recording is that of distinguishing the activities of many neurons. Here, we develop a framework, based on Fisher information, to quantify how separable a neuron's activity is from the activities of nearby neurons.…

The human visual system is capable of processing continuous streams of visual information, but how the brain encodes and retrieves recent visual memories during continuous visual processing remains unexplored. This study investigates the…

Computation and Language · Computer Science 2024-10-01 Runze Xia , Congchi Yin , Piji Li

Large efforts are currently under way to systematically map functional connectivity between all pairs of millimeter-scale brain regions using big volumes of neuroimaging data. Functional magnetic resonance imaging (fMRI) can produce these…

Neurons and Cognition · Quantitative Biology 2014-09-24 Enzo Tagliazucchi , Helmut Laufs , Dante R. Chialvo

In this paper, we present contemporary techniques for visualising the feature space of a deep learning image classification neural network. These techniques are viewed in the context of a feed-forward network trained to classify low…

Computer Vision and Pattern Recognition · Computer Science 2018-11-16 Ezra Webb , Cheng Lei , Chun-Jung Huang , Hirofumi Kobayashi , Hideharu Mikami , Keisuke Goda

A multilayered particle is illuminated by plane acoustic or electromagnetic waves of one or several frequencies. We consider the inverse scattering problem for the identification of the layers and of the refraction coefficients of the…

Mathematical Physics · Physics 2016-09-07 Semion Gutman

Non-invasive and single-shot holographic imaging through complex media is technically challenging due to random light scattering which significantly scrambles optical information. Recently, several methods have been presented to address…

We introduce a method that takes advantage of high-quality pretrained multimodal representations to explore fine-grained semantic networks in the human brain. Previous studies have documented evidence of functional localization in the…

Artificial Intelligence · Computer Science 2023-06-07 Cory Efird , Alex Murphy , Joel Zylberberg , Alona Fyshe

Recently, deep learning-based denoising approaches have led to dramatic improvements in low sample-count Monte Carlo rendering. These approaches are aimed at path tracing, which is not ideal for simulating challenging light transport…

Graphics · Computer Science 2020-04-28 Shilin Zhu , Zexiang Xu , Henrik Wann Jensen , Hao Su , Ravi Ramamoorthi

Functional MRI (fMRI) is a powerful technique that has allowed us to characterize visual cortex responses to stimuli, yet such experiments are by nature constructed based on a priori hypotheses, limited to the set of images presented to the…

Neurons and Cognition · Quantitative Biology 2021-05-18 Zijin Gu , Keith W. Jamison , Meenakshi Khosla , Emily J. Allen , Yihan Wu , Thomas Naselaris , Kendrick Kay , Mert R. Sabuncu , Amy Kuceyeski

Modeling the propagation of light through disordered media is central to understanding and controlling wave transport in diverse optical and mesoscopic applications. Here, we present a random matrix simulation framework for modeling the…

Optics · Physics 2026-02-24 Niall Byrnes , Sulagna Dutta , Matthew R. Foreman

This is the first article in a series of two dealing with a matrix approach for aberration quantification and correction in ultrasound imaging. Advanced synthetic beamforming relies on a double focusing operation at transmission and…

Applied Physics · Physics 2022-12-06 William Lambert , Justine Robin , Laura A. Cobus , Mathias Fink , Alexandre Aubry

Functional data analysis deals with data recorded densely over time (or any other continuum) with one or more observed curves per subject. Conceptually, functional data are continuously defined, but in practice, they are usually observed at…

Methodology · Statistics 2023-01-20 Chengqian Xian , Camila de Souza , John Jewell , Ronaldo Dias

This paper introduces a new method of data-driven microscope design for virtual fluorescence microscopy. Our results show that by including a model of illumination within the first layers of a deep convolutional neural network, it is…

Image and Video Processing · Electrical Eng. & Systems 2020-04-23 Colin L. Cooke , Fanjie Kong , Amey Chaware , Kevin C. Zhou , Kanghyun Kim , Rong Xu , D. Michael Ando , Samuel J. Yang , Pavan Chandra Konda , Roarke Horstmeyer

Many analyses of functional magnetic resonance imaging (fMRI) examine functional connectivity (FC), or the statistical dependencies among distant brain regions. These analyses are typically exploratory, guiding future confirmatory research.…

Applications · Statistics 2025-10-20 Kyle Stanley , Nicole Lazar , Matthew Reimherr

Reconstructing visual stimuli from human brain activity (e.g., fMRI) bridges neuroscience and computer vision by decoding neural representations. However, existing methods often overlook critical brain structure-function relationships,…

Computer Vision and Pattern Recognition · Computer Science 2025-07-23 Sijin Yu , Zijiao Chen , Wenxuan Wu , Shengxian Chen , Zhongliang Liu , Jingxin Nie , Xiaofen Xing , Xiangmin Xu , Xin Zhang

Machine learning applied to computer vision and signal processing is achieving results comparable to the human brain on specific tasks due to the great improvements brought by the deep neural networks (DNN). The majority of state-of-the-art…

Computer Vision and Pattern Recognition · Computer Science 2020-06-30 José Augusto Stuchi , Levy Boccato , Romis Attux

Median filtering is a cornerstone of computational image processing. It provides an effective means of image smoothing, with minimal blurring or softening of edges, invariance to monotonic transformations such as gamma adjustment, and…

Computer Vision and Pattern Recognition · Computer Science 2025-05-30 Ben Weiss
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