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Nonlinear oscillations of a bubble carrying a constant charge and suspended in a fluid, undergoing periodic forcing due to incident ultrasound are studied. The system exhibits period-doubling route to chaos and the presence of charge has…

Chaotic Dynamics · Physics 2025-07-11 Thotreithem Hongray , B. Ashok , J. Balakrishnan

The mechanical properties of cells play key roles in their physiology, function, physiological and pathological transformations. Micro-elastography has recently emerged as a promising tool to estimate cellular viscoelastic properties within…

A growing class of ultrasound-mediated diagnostic and therapeutic technologies, including sonoporation and blood-brain barrier modulation, relies on microbubble contrast agents, where precise control of microbubble dynamics governs…

Instrumentation and Detectors · Physics 2025-12-30 Hohyun Lee , Reza Pakdaman Zangabad , Chulyong Kim , Victor Menezes , Juyoung Park , F. Levent Degertekin , Costas Arvanitis

Monodisperse microbubble ultrasound contrast agents have been proposed to further increase the signal-to-noise-ratio of contrast enhanced ultrasound imaging. Here, the sensitivity of a polydisperse preclinical agent was compared…

Medical Physics · Physics 2018-06-13 Tim Segers , Pieter Kruizinga , Maarten Kok , Guillaume Lajoinie , Nico de Jong , Michel Versluis

Monodisperse lipid-coated microbubbles are a promising route to unlock the full potential of ultrasound contrast agents for medical diagnosis and therapy. Here, we present a stand-alone lab-on-a-chip instrument that allows microbubbles to…

The dynamics of bubble clouds induced by high-intensity focused ultrasound are investigated in a regime where the cloud size is similar to the ultrasound wavelength. High-speed images show that the cloud is asymmetrical; the bubbles nearest…

Fluid Dynamics · Physics 2019-02-20 Kazuki Maeda , Tim Colonius

The duality between deformations of elastic bodies and non-inertial flows in viscous liquids has been a guiding principle in decades of research. However, this duality is broken when a spheroidal or other doubly-curved liquid film is…

Soft Condensed Matter · Physics 2023-07-20 Benny Davidovitch , Avraham Klein

Yield-stress fluids naturally trap small bubbles when their buoyancy applies an insufficient stress to induce local yielding of the material. Under acoustic excitation, trapped bubbles can be driven into volumetric oscillations and apply an…

Soft Condensed Matter · Physics 2020-11-02 Brice Saint-Michel , Valeria Garbin

We present a computational study of the behaviour of a lipid-coated SonoVue microbubble with initial radius $1 \, \mu \text{m} \leq R_0 \leq 2 \, \mu \text{m}$, excited at frequencies (200-1500 kHz) significantly below the linear resonance…

Fluid Dynamics · Physics 2022-01-17 Jonas Gümmer , Sören Schenke , Fabian Denner

The paper describes a study of wet foams in microgravity whose bubble size distribution evolves due to diffusive gas exchange. We focus on the comparison between the size of bubbles determined from images of the foam surface and the size of…

Motivated by the buckling of glassy crusts formed on evaporating droplets of polymer and colloid solutions, we numerically model the deformation and buckling of spherical elastic caps controlled by varying the volume between the shell and…

Materials Science · Physics 2009-11-11 D. A. Head

The viscosity of lipid bilayer membranes plays an important role in determining the diffusion constant of embedded proteins and the dynamics of membrane deformations, yet it has historically proven very difficult to measure. Here we…

Soft Condensed Matter · Physics 2013-08-30 Aurelia R. Honerkamp-Smith , Francis G. Woodhouse , Vasily Kantsler , Raymond E. Goldstein

Subharmonics emitted from microbubble-based ultrasound contrast agents (UCA) are considered as a noninvasive indicator for diagnostic applications in medical fields. Contrast ultrasound imaging using the modality of subharmonics could be…

Medical Physics · Physics 2021-04-13 Lang Xia

The first stages of the path instability phenomenon known to affect the buoyancy-driven motion of gas bubbles rising in weakly or moderately viscous liquids are examined thanks to a recently developed numerical tool designed to assess the…

Fluid Dynamics · Physics 2023-12-21 P. Bonnefis , J. Sierra-Ausin , D. Fabre , J. Magnaudet

The formation and evolution of immersed surface micro- and nanobubbles are essential in various practical applications, such as the usage of superhydrophobic rematerials, drug delivery, and mineral flotation. In this work, we investigate…

The dynamic response of a gas bubble entrapped in a cavity on the surface of a submerged solid subject to an acoustic field is investigated in the linear approximation. We derive semi-analytical expressions for the resonance frequency,…

Viscosity is an important property of out-of-equilibrium systems such as active biological materials and driven non-Newtonian fluids, and for fields ranging from biomaterials to geology, energy technologies and medicine. However,…

Super-resolution ultrasound can image microvascular structure and flow at sub-wave-diffraction resolution based on localising and tracking microbubbles. Currently, tracking microbubbles accurately under limited imaging frame rates and high…

Image and Video Processing · Electrical Eng. & Systems 2023-04-04 Biao Huang , Jipeng Yan , Megan Morris , Victoria Sinnett , Navita Somaiah , Meng-Xing Tang

The scattering of ultrasound from bubbles of micrometer-sized radius, such as used in contrast enhancers for ultrasound diagnostics, is studied. We show that sound scattering and ``active'' emission of sound from oscillating bubbles are not…

Soft Condensed Matter · Physics 2009-10-31 Sascha Hilgenfeldt , Detlef Lohse , Michael Zomack

Accurate measurement of dynamic contact angles in aqueous environments is essential for evaluating surface wettability. However, conventional captive bubble methods often suffer from limitations such as bubble instability and interference…

Soft Condensed Matter · Physics 2026-05-13 Koki Iwasaki , Hiroyuki Ebata , Hiroaki Katsuragi