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Machines enabled the Industrial Revolution and are central to modern technological progress: A machine's parts transmit forces, motion, and energy to one another in a predetermined manner. Today's engineering frontier, building artificial…

Soft Condensed Matter · Physics 2021-11-18 A. Aubret , Q. Martinet , J. Palacci

Recent electronic transport experiments using metallic contacts attached to proteins identified some 'stylized facts' which contradict conventional wisdom that increasing either the spatial distance between the electrodes or the temperature…

Disordered Systems and Neural Networks · Physics 2019-09-04 Eszter Papp , Dávid P. Jelenfi , Máté T. Veszeli , Gábor Vattay

Biological membranes mainly consist of lipids and proteins. While the proteins have many functions as single molecules, the membrane as a whole displays physical properties that cannot be explained on the single molecule level. For example,…

Biological Physics · Physics 2009-06-09 Thomas Heimburg

Nanofluidics, the field interested in flows at the smallest scales, has grown at a fast pace, reaching an ever finer control offluidic and ionic transport at the molecular level. Still, artificial pores are far from reaching the wealth of…

Soft Condensed Matter · Physics 2023-05-10 Paul Robin , Lydéric Bocquet

Membrane pores are implicated in several critical functions, including cell fusion and the transport of signaling molecules for intercellular communication. However, these structural features are often difficult to probe directly. Droplet…

Soft Condensed Matter · Physics 2025-11-13 Nivedina A. Sarma , David A. King , Xuefei Wu , Brett A. Helms , Paul D. Ashby , Thomas P. Russell , Ahmad K. Omar

We investigate membrane-mediated interactions between transmembrane proteins using coarse-grained models. We compare the effective potential of mean force (PMF) between two proteins, which are always aligned parallel to the z-axis of the…

Biological Physics · Physics 2012-04-11 Joerg Neder , Beate West , Peter Nielaba , Friederike Schmid

Ferromagnetic, in contrast to antiferromagnetic, Heisenberg chains can undergo a Spin-Peierls dimerization only at finite temperatures. They show reentrant behavior as a function of temperature, which might play a role for systems with…

Strongly Correlated Electrons · Physics 2011-10-19 A. Herzog , P. Horsch , A. M. Oles , J. Sirker

Proteins fold to a specific functional conformation with a densely packed hydrophobic core that controls their stability. We develop a geometric, yet all-atom model for proteins that explains the universal core packing fraction of…

Soft Condensed Matter · Physics 2025-03-28 Alex T. Grigas , Zhuoyi Liu , Jack A. Logan , Mark D. Shattuck , Corey S. O'Hern

A multiphysics modeling approach for heat conduction in metal hydride powders is presented, including particle shape distribution, size distribution, granular packing structure, and effective thermal conductivity. A statistical geometric…

Soft Condensed Matter · Physics 2014-11-03 Kyle C. Smith , Timothy S. Fisher

A superconductor with a gap in the density of states or a quantum dot with discrete energy levels is a central building block in realizing an electronic on-chip cooler. They can work as energy filters, allowing only hot quasiparticles to…

Mesoscale and Nanoscale Physics · Physics 2012-03-26 Juha T. Muhonen , Matthias Meschke , Jukka P. Pekola

Thermal unfolding of proteins is compared to folding and mechanical stretching in a simple topology-based dynamical model. We define the unfolding time and demonstrate its low-temperature divergence. Below a characteristic temperature,…

Biomolecules · Quantitative Biology 2009-11-13 Marek Cieplak , Joanna I. Sulkowska

Magnetic skyrmions are topologically-distinct swirls of magnetic moments which display particle-like behaviour, including the ability to undergo thermally-driven diffusion. In this paper we study the thermally activated motion of arrays of…

Mesoscale and Nanoscale Physics · Physics 2021-11-03 Yifan Zhou , Rhodri Mansell , Tapio Ala-Nissila , Sebastiaan van Dijken

We elucidate the physics of the dynamical transition via 10-100ns molecular dynamics simulations at temperatures spanning 160-300K. By tracking the energy fluctuations, we show that the protein dynamical transition is marked by a cross-over…

Quantitative Methods · Quantitative Biology 2009-06-17 Osman Burak Okan , Ali Rana Atilgan , Canan Atilgan

Mimicking vascular systems in living beings, designers have realized microvascular composites to achieve thermal regulation and other functionalities, such as electromagnetic modulation, sensing, and healing. Such material systems avail…

Numerical Analysis · Mathematics 2024-01-30 Kalyana B. Nakshatrala

Peripheral membrane proteins can reversibly and specifically bind to biological membranes to carry out functions such as cell signalling, enzymatic activity, or membrane remodelling. Structures of these proteins and of their lipid-binding…

Biological Physics · Physics 2023-11-14 Andreas Haahr Larsen , Laura H. John , Mark S. P. Sansom , Robin A. Corey

Colloidosomes are created in the laboratory from a Pickering emulsion of water droplets in oil. The colloidosomes have approximately the same diameter and by choosing (hairy) particles of different diameters it is possible to control the…

Chemical Physics · Physics 2012-11-20 Riccardo Fantoni , Johannes W. O. Salari , Bert Klumperman

The paper shows how the diffusive movement of ions through a channel protein can be described as a chemical reaction over an arbitrary shaped potential barrier. The result is simple and intuitive but without approximation beyond the…

Biomolecules · Quantitative Biology 2008-07-10 Bob Eisenberg

We construct a Hamiltonian for a single domain protein where the contact enthalpy and the chain entropy decrease linearly with the number of native contacts. The hydration effect upon protein unfolding is included by modeling water as ideal…

Condensed Matter · Physics 2009-11-07 Audun Bakk , Johan S. Hoye , Alex Hansen

Protein structures are a very special class among all possible structures. It was suggested that a ``designability principle'' plays a crucial role in nature's selection of protein sequences and structures. Here we provide a theoretical…

Statistical Mechanics · Physics 2009-10-30 Hao Li , Chao Tang , Ned S. Wingreen

Microgels are often discussed as well-suited model system for soft colloids. In contrast to rigid spheres, the microgel volume and, coupled to this, the volume fraction in dispersion can be manipulated by external stimuli. This behavior is…

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