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Branched actin networks at the leading edge of a crawling cell evolve via protein-regulated processes such as polymerization, depolymerization, capping, branching, and severing. A formulation of these processes is presented and analyzed to…

Soft Condensed Matter · Physics 2009-11-13 Ajay Gopinathan , Kun-Chun Lee , J. M. Schwarz , Andrea J. Liu

We study the dynamics of an interface (active domain) between different absorbing regions in models with two absorbing states in one dimension; probabilistic cellular automata models and interacting monomer-dimer models. These models…

Statistical Mechanics · Physics 2009-10-31 Sungchul Kwon , WonMuk Hwang , Hyunggyu Park

Cell-cell adhesion is one the most fundamental mechanisms regulating collective cell migration during tissue development, homeostasis and repair, allowing cell populations to self-organize and eventually form and maintain complex tissue…

Cell Behavior · Quantitative Biology 2022-11-16 Carles Falcó , Ruth E. Baker , José A. Carrillo

Interfaces in two-dimensional systems exhibit unexpected complex dynamical behaviors, the dynamics of a border connecting a stripe pattern and a uniform state is studied. Numerical simulations of a prototype isotropic model, the subcritical…

Pattern Formation and Solitons · Physics 2008-06-05 Marcel G. Clerc , Daniel Escaff , Rene Rojas

We present initial results regarding the existence, stability and interaction of linear and nonlinear vibrational modes in a system of two coupled, one dimensional lattices with unequal numbers of masses. The effects on these nonlinear…

Biological Physics · Physics 2007-05-23 Kyle Forinash

This letter is concerned with asymptotic analysis of a PDE model for motility of a eukaryotic cell on a substrate. This model was introduced in [1], where it was shown numerically that it successfully reproduces experimentally observed…

Analysis of PDEs · Mathematics 2016-04-12 Leonid Berlyand , Mykhailo Potomkin , Volodymyr Rybalko

Signaling pathways are responsible for the regulation of cell processes, such as monitoring the external environment, transmitting information across membranes, and making cell fate decisions. Given the increasing amount of biological data…

Molecular Networks · Quantitative Biology 2020-04-07 Daniel Inostroza , Cecilia Hernández , Diego Seco , Gonzalo Navarro , Alvaro Olivera-Nappa

Space-time varying media with moving interfaces unlock new ways to manipulate electromagnetic waves. Yet, analytical solutions have been mostly limited to interfaces moving at constant velocity or constant proper acceleration. Here, we…

Optics · Physics 2025-10-10 Klaas De Kinder , Amir Bahrami , Christophe Caloz

We continue our analysis of the coupling between nonlinear hyperbolic problems across possibly resonant interfaces. In the first two parts of this series, we introduced a new framework for coupling problems which is based on the so-called…

Analysis of PDEs · Mathematics 2022-07-26 Benjamin Boutin , Frédéric Coquel , Philippe G. LeFloch

A novel thermodynamically consistent diffuse interface model is derived for compressible electrolytes with phase transitions. The fluid mixtures may consist of N constituents with the phases liquid and vapor, where both phases may coexist.…

Analysis of PDEs · Mathematics 2014-11-13 Wolfgang Dreyer , Jan Giesselmann , Christiane Kraus

Inspired by recent experimental observation of patterning at the membrane of a living cell, we propose a generic model for the dynamics of a fluctuating interface driven by particle-like inclusions which stimulate its growth. We find that…

Soft Condensed Matter · Physics 2019-07-25 F. Cagnetta , M. R. Evans , D. Marenduzzo

We present a single, unified, multi-scale model to study the attachment\detachment dynamics of two deforming, near spherical cells, coated with binding ligands and subject to a slow, homogeneous shear flow in a viscous fluid medium. The…

Cell Behavior · Quantitative Biology 2015-04-23 Sarthok Sircar , Anthony J. Roberts

The seven-equation model is a compressible multiphase formulation that allows for phasic velocity and pressure disequilibrium. These equations are solved using a diffused interface method that models resolved multiphase flows. Novel…

Fluid Dynamics · Physics 2023-01-24 Achyut Panchal , Spencer H. Bryngelson , Suresh Menon

A diffuse interface (phase field) model for an electrochemical system is developed. We describe the minimal set of components needed to model an electrochemical interface and present a variational derivation of the governing equations. With…

Materials Science · Physics 2007-05-23 J. E. Guyer , W. J. Boettinger , J. A. Warren , G. B. McFadden

Based on the thermodynamic variation, we rigorously derive the sharp-interface model for solid-state dewetting on a flat substrate in the form of cylindrical symmetry. The governing equations for the model belong to fourth-order geometric…

Materials Science · Physics 2018-05-22 Quan Zhao

This paper presents a general and robust method for the fluid-structure interaction of membranes and shells undergoing large displacement and large added-mass effects by coupling an immersed-boundary method with a shell finite-element…

Fluid Dynamics · Physics 2023-08-15 Marin Lauber , Gabriel D. Weymouth , Georges Limbert

We consider a diffuse interface model describing a ternary system constituted by a conductive diblock copolymer and a homopolymer acting as solvent. The resulting dynamics is modeled by two Cahn--Hilliard--Oono equations for the copolymer…

Analysis of PDEs · Mathematics 2024-11-07 Helmut Abels , Andrea Di Primio , Harald Garcke

We investigate the sharp material interface limit of the Darcy-Boussinesq model for convection in layered porous media with diffused material interfaces, which allow a gradual transition of material parameters between different layers. We…

Analysis of PDEs · Mathematics 2025-04-25 Hongjie Dong , Xiaoming Wang

Under dehydration conditions, amphipathic Late Embryogenesis Abundant (LEA) proteins fold spontaneously from a random conformation into alpha-helical structures and this transition is promoted by the presence of membranes. To gain insight…

Biological Physics · Physics 2012-06-27 Sergey Pogodin , Nigel K. H. Slater , Vladimir A. Baulin

We introduce a phase field approach for diffusion inside and outside a closed cell with damping and with source terms at the interface. The method is compared to exact solutions (where possible) and the more traditional finite element…

Statistical Mechanics · Physics 2007-05-23 Julien Kockelkoren , Herbert Levine , Wouter-Jan Rappel