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Deep generative models have emerged as promising tools for detecting arbitrary anomalies in data, dispensing with the necessity for manual labelling. Recently, autoregressive transformers have achieved state-of-the-art performance for…

Over recent years, denoising diffusion generative models have come to be considered as state-of-the-art methods for synthetic data generation, especially in the case of generating images. These approaches have also proved successful in…

Machine Learning · Computer Science 2023-06-30 Stratis Limnios , Praveen Selvaraj , Mihai Cucuringu , Carsten Maple , Gesine Reinert , Andrew Elliott

Generative models, particularly diffusion models, have made significant success in data synthesis across various modalities, including images, videos, and 3D assets. However, current diffusion models are computationally intensive, often…

Computer Vision and Pattern Recognition · Computer Science 2024-12-10 Yuanzhi Zhu , Hanshu Yan , Huan Yang , Kai Zhang , Junnan Li

We develop an unsupervised probabilistic model for heterogeneous Electronic Health Record (EHR) data. Utilizing a mixture model formulation, our approach directly models sequences of arbitrary length, such as medications and laboratory…

Machine Learning · Computer Science 2022-09-02 Alan D. Kaplan , John D. Greene , Vincent X. Liu , Priyadip Ray

Time series in Electronic Health Records (EHRs) present unique challenges for generative models, such as irregular sampling, missing values, and high dimensionality. In this paper, we propose a novel generative adversarial network (GAN)…

Machine Learning · Computer Science 2024-02-12 Hojjat Karami , Mary-Anne Hartley , David Atienza , Anisoara Ionescu

Magnetic resonance (MR) imaging, including cardiac MR, is prone to domain shift due to variations in imaging devices and acquisition protocols. This challenge limits the deployment of trained AI models in real-world scenarios, where…

Computer Vision and Pattern Recognition · Computer Science 2025-08-11 Xin Ci Wong , Duygu Sarikaya , Kieran Zucker , Marc De Kamps , Nishant Ravikumar

The lack of real-world data in clinical fields poses a major obstacle in training effective AI models for diagnostic and preventive tools in medicine. Generative AI has shown promise in increasing data volume and enhancing model training,…

Machine Learning · Computer Science 2026-02-10 Md Shahriar Kabir , Sana Alamgeer , Minakshi Debnath , Anne H. H. Ngu

The widespread adoption of electronic health records and digital healthcare data has created a demand for data-driven insights to enhance patient outcomes, diagnostics, and treatments. However, using real patient data presents privacy and…

Machine Learning · Computer Science 2023-11-15 Aryan Jadon , Shashank Kumar

Diffusion models and flow-matching models have enabled generating diverse and realistic images by learning to transfer noise to data. However, sampling from these models involves iterative denoising over many neural network passes, making…

Machine Learning · Computer Science 2025-06-24 Kevin Frans , Danijar Hafner , Sergey Levine , Pieter Abbeel

Privacy concerns around sharing personally identifiable information are a major practical barrier to data sharing in medical research. However, in many cases, researchers have no interest in a particular individual's information but rather…

Image and Video Processing · Electrical Eng. & Systems 2021-08-18 August DuMont Schütte , Jürgen Hetzel , Sergios Gatidis , Tobias Hepp , Benedikt Dietz , Stefan Bauer , Patrick Schwab

Electronic Health Records (EHR)-based disease prediction models have demonstrated significant clinical value in promoting precision medicine and enabling early intervention. However, existing large language models face two major challenges:…

Computation and Language · Computer Science 2025-06-19 Junke Wang , Hongshun Ling , Li Zhang , Longqian Zhang , Fang Wang , Yuan Gao , Zhi Li

Recent advancements in diffusion models have significantly improved performance in super-resolution (SR) tasks. However, previous research often overlooks the fundamental differences between SR and general image generation. General image…

Image and Video Processing · Electrical Eng. & Systems 2024-10-31 Hanlin Wu , Jiangwei Mo , Xiaohui Sun , Jie Ma

Diffusion models have established themselves as state-of-the-art generative models across various data modalities, including images and videos, due to their ability to accurately approximate complex data distributions. Unlike traditional…

Machine Learning · Computer Science 2025-10-23 Daniel Wesego

Denoising-based models, including diffusion and flow matching, have led to substantial advances in graph generation. Despite this progress, such models remain constrained by two fundamental limitations: a computational cost that scales…

Machine Learning · Computer Science 2026-04-02 Yoann Boget , Pablo Strasser , Alexandros Kalousis

AI models present a wide range of applications in the field of medicine. However, achieving optimal performance requires access to extensive healthcare data, which is often not readily available. Furthermore, the imperative to preserve…

Employing a forward diffusion chain to gradually map the data to a noise distribution, diffusion-based generative models learn how to generate the data by inferring a reverse diffusion chain. However, this approach is slow and costly…

Machine Learning · Statistics 2023-09-08 Huangjie Zheng , Pengcheng He , Weizhu Chen , Mingyuan Zhou

Diffusion models have enabled remarkably high-quality medical image generation, yet it is challenging to enforce anatomical constraints in generated images. To this end, we propose a diffusion model-based method that supports…

Image and Video Processing · Electrical Eng. & Systems 2024-06-21 Nicholas Konz , Yuwen Chen , Haoyu Dong , Maciej A. Mazurowski

The scarcity of large-scale palmprint databases poses a significant bottleneck to advancements in contactless palmprint recognition. To address this, researchers have turned to synthetic data generation. While Generative Adversarial…

Computer Vision and Pattern Recognition · Computer Science 2024-06-04 Steven A. Grosz , Anil K. Jain

Denoising Diffusion Probabilistic Models have shown extraordinary ability on various generative tasks. However, their slow inference speed renders them impractical in speech synthesis. This paper proposes a linear diffusion model (LinDiff)…

Sound · Computer Science 2023-06-13 Haogeng Liu , Tao Wang , Jie Cao , Ran He , Jianhua Tao

Diffusion models have achieved remarkable success in generating high-resolution, realistic images across diverse natural distributions. However, their performance heavily relies on high-quality training data, making it challenging to learn…

Machine Learning · Computer Science 2025-05-22 Tianyu Chen , Yasi Zhang , Zhendong Wang , Ying Nian Wu , Oscar Leong , Mingyuan Zhou