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This work presents the first steps to modelling synthetic rovibrational spectra for all molecules of astrophysical interest using a new approach implemented in the Prometheus code. The goal is to create a new comprehensive source of…

Chemical Physics · Physics 2022-02-02 Thomas M. Cross , David M. Benoit , Marco Pignatari , Brad K. Gibson

A central problem in biophysics and computational drug design is accurate modeling of biomolecules. The current molecular dynamics simulation methods can answer how a molecule inhibits a cancerous cell signaling pathway, or the role of…

Quantum Physics · Physics 2019-10-31 Anurag Mishra , Alireza Shabani

Vibronic spectra of molecules are typically described within the Franck-Condon model. Here, we show that highly resolved vibronic spectra of large organic molecules on a single layer of MoS$_{2}$ on Au(111) show spatial variations in their…

Mesoscale and Nanoscale Physics · Physics 2020-03-24 Gaël Reecht , Nils Krane , Christian Lotze , Lei Zhang , Alejandro L. Briseno , Katharina J. Franke

Interpretation of vibrational inelastic neutron scattering spectra of complex systems is frequently reliant on accompanying simulations from theoretical models. Ab-initio codes can routinely generate force constants, but additional steps…

Materials Science · Physics 2022-08-11 Rebecca Fair , Adam Jackson , David Voneshen , Dominik Jochym , Duc Le , Keith Refson , Toby Perring

Protein structure prediction is a core challenge in computational biology, particularly for fragments within ligand-binding regions, where accurate modeling is still difficult. Quantum computing offers a novel first-principles modeling…

Emerging Technologies · Computer Science 2025-08-05 Yuqi Zhang , Yuxin Yang , Cheng-Chang Lu , Weiwen Jiang , Feixiong Cheng , Bo Fang , Qiang Guan

We present the implementation of a variational finite element solver in the HelFEM program for benchmark calculations on diatomic systems. A basis set of the form $\chi_{nlm}(\mu,\nu,\phi)=B_{n}(\mu)Y_{l}^{m}(\nu,\phi)$ is used, where…

Chemical Physics · Physics 2019-08-19 Susi Lehtola

In this paper, we report high-precision absolute distance and vibration measurements performed with frequency scanned interferometry using a pair of single-mode optical fibers. Absolute distance was determined by counting the interference…

Instrumentation and Detectors · Physics 2008-11-26 Hai-Jun Yang , Sven Nybery , Keith Riles

The imitation of percussive instruments via the human voice is a natural way for us to communicate rhythmic ideas and, for this reason, it attracts the interest of music makers. Specifically, the automatic mapping of these vocal imitations…

Audio and Speech Processing · Electrical Eng. & Systems 2020-09-25 Alejandro Delgado , SKoT McDonald , Ning Xu , Mark Sandler

We show that the DCSD (distinguishable clusters with all singles and doubles) correlation method permits the calculation of vibrational spectra at near-CCSD(T) quality but at no more than CCSD cost, and with comparatively inexpensive…

Chemical Physics · Physics 2017-12-27 Manoj K. Kesharwani , Nitai Sylvetsky , Jan M. L. Martin

Most of the existing quantum neural network models, such as variational quantum circuits (VQCs), are limited in their ability to explore the non-linear relationships in input data. This gradually becomes the main obstacle for it to tackle…

Quantum Physics · Physics 2024-02-14 Jinyang Li , Ang Li , Weiwen Jiang

We introduce the Cyclic Variational Quantum Eigensolver (CVQE), a hardware-efficient framework for accurate ground-state quantum simulation on noisy intermediate-scale quantum (NISQ) devices. CVQE departs from conventional VQE by…

Quantum Physics · Physics 2025-09-17 Hao Zhang , Ayush Asthana

Developing improved predictive models for multi-molecular systems is crucial, as nearly every chemical product used results from a mixture of chemicals. While being a vital part of the industry pipeline, the chemical mixture space remains…

A new semiclassical "divide-and-conquer" method is presented with the aim of demonstrating that quantum dynamics simulations of high dimensional molecular systems are doable. The method is first tested by calculating the quantum vibrational…

Chemical Physics · Physics 2017-07-11 Michele Ceotto , Giovanni Di Liberto , Riccardo Conte

Spatialized vibrotactile feedback systems deliver tactile information by placing multiple vibrotactile actuators on the body. As increasing numbers of actuators are required to adequately convey information in complicated applications,…

Human-Computer Interaction · Computer Science 2025-02-14 Bingjian Huang , Siyi Ren , Yuewen Luo , Qilong Cheng , Hanfeng Cai , Yeqi Sang , Mauricio Sousa , Paul H. Dietz , Daniel Wigdor

A MHz gravitational wave search for harmonic sources was conducted using a 704-hr dataset obtained from the Holometer, a pair of 40-meter power recycled Michelson interferometers. Our search was designed to look for cosmic string loops and…

Instrumentation and Methods for Astrophysics · Physics 2020-10-14 Jeronimo G. C. Martinez , Brittany Kamai

Background: The volume of distribution at steady state (VDss) is a fundamental pharmacokinetics (PK) property of drugs, which measures how effectively a drug molecule is distributed throughout the body. Along with the clearance (CL), it…

Quantitative Methods · Quantitative Biology 2022-11-11 Wenwen Liu , Cheng Luo , Hecheng Wang , Fanwang Meng

In vitro cellular experimentation with genetic interventions, using for example CRISPR technologies, is an essential step in early-stage drug discovery and target validation that serves to assess initial hypotheses about causal associations…

Machine Learning · Computer Science 2021-10-25 Arash Mehrjou , Ashkan Soleymani , Andrew Jesson , Pascal Notin , Yarin Gal , Stefan Bauer , Patrick Schwab

Birdsong often contains large amounts of rapid frequency modulation (FM). It is believed that the use or otherwise of FM is adaptive to the acoustic environment, and also that there are specific social uses of FM such as trills in…

Sound · Computer Science 2015-09-22 Dan Stowell , Mark D. Plumbley

We present a new analysis of the profile data from the 47 millisecond pulsars comprising the 12.5-year data set of the North American Nanohertz Observatory for Gravitational Waves (NANOGrav), which is presented in a parallel paper (Alam et…