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Social Determinants of Health (SDOH), also known as Health-Related Social Needs (HSRN), play a significant role in patient health outcomes. The Centers for Disease Control and Prevention (CDC) introduced a subset of ICD-10 codes called…

Artificial Intelligence · Computer Science 2026-01-16 Akul Goel , Surya Narayanan Hari , Belinda Waltman , Matt Thomson

In this study, we investigated the application of bio-inspired optimization algorithms, including Genetic Algorithm, Particle Swarm Optimization, and Whale Optimization Algorithm, for feature selection in chronic disease prediction. The…

Neural and Evolutionary Computing · Computer Science 2024-01-12 Abeer Dyoub , Ivan Letteri

Most research studying social determinants of health (SDoH) has focused on physician notes or structured elements of the electronic medical record (EMR). We hypothesize that clinical notes from social workers, whose role is to ameliorate…

Computation and Language · Computer Science 2022-12-06 Shenghuan Sun , Travis Zack , Madhumita Sushil , Atul J. Butte

Social determinants of health (SDOH) affect health outcomes, and knowledge of SDOH can inform clinical decision-making. Automatically extracting SDOH information from clinical text requires data-driven information extraction models trained…

Computation and Language · Computer Science 2021-03-12 Kevin Lybarger , Mari Ostendorf , Meliha Yetisgen

Objective: We aim to develop an open-source natural language processing (NLP) package, SODA (i.e., SOcial DeterminAnts), with pre-trained transformer models to extract social determinants of health (SDoH) for cancer patients, examine the…

Heart Failure (HF) affects millions of Americans and leads to high readmission rates, posing significant healthcare challenges. While Social Determinants of Health (SDOH) such as socioeconomic status and housing stability play critical…

Machine Learning · Computer Science 2025-09-29 Mingchen Shao , Youjeong Kang , Xiao Hu , Hyunjung Gloria Kwak , Carl Yang , Jiaying Lu

The classification of clinical notes into specific diagnostic categories is critical in healthcare, especially for mental health conditions like Anxiety and Adjustment Disorder. In this study, we compare the performance of various…

Alzheimer's disease and related dementias (AD/ADRD) represent a growing healthcare crisis affecting over 6 million Americans. While genetic factors play a crucial role, emerging research reveals that social determinants of health (SDOH)…

Quantitative Methods · Quantitative Biology 2025-03-24 Bereket Kindo , Arjee Restar , Anh Tran

The generation of synthetic clinical trial data offers a promising approach to mitigating privacy concerns and data accessibility limitations in medical research. However, ensuring that synthetic datasets maintain high fidelity, utility,…

Machine Learning · Computer Science 2025-12-16 Waldemar Hahn , Jan-Niklas Eckardt , Christoph Röllig , Martin Sedlmayr , Jan Moritz Middeke , Markus Wolfien

Objective: The n2c2/UW SDOH Challenge explores the extraction of social determinant of health (SDOH) information from clinical notes. The objectives include the advancement of natural language processing (NLP) information extraction…

Computation and Language · Computer Science 2023-02-15 Kevin Lybarger , Meliha Yetisgen , Özlem Uzuner

Since clinical letters contain sensitive information, clinical-related datasets can not be widely applied in model training, medical research, and teaching. This work aims to generate reliable, various, and de-identified synthetic clinical…

Computation and Language · Computer Science 2024-09-17 Libo Ren , Samuel Belkadi , Lifeng Han , Warren Del-Pinto , Goran Nenadic

Since no effective therapies exist for Alzheimer's disease (AD), prevention has become more critical through lifestyle factor changes and interventions. Analyzing electronic health records (EHR) of patients with AD can help us better…

Computation and Language · Computer Science 2021-01-26 Zitao Shen , Yoonkwon Yi , Anusha Bompelli , Fang Yu , Yanshan Wang , Rui Zhang

The extraction and analysis of insights from medical data, primarily stored in free-text formats by healthcare workers, presents significant challenges due to its unstructured nature. Medical coding, a crucial process in healthcare, remains…

Computation and Language · Computer Science 2024-05-28 Mikhail Kulyabin , Gleb Sokolov , Aleksandr Galaida , Andreas Maier , Tomas Arias-Vergara

Clinical notes contain information about patients that goes beyond structured data like lab values and medications. However, clinical notes have been underused relative to structured data, because notes are high-dimensional and sparse. This…

Computation and Language · Computer Science 2020-12-01 Kexin Huang , Jaan Altosaar , Rajesh Ranganath

Objective: The 2022 n2c2 NLP Challenge posed identification of social determinants of health (SDOH) in clinical narratives. We present three systems that we developed for the Challenge and discuss the distinctive task formulation used in…

Computation and Language · Computer Science 2023-01-30 Manabu Torii , Ian M. Finn , Son Doan , Paul Wang , Elly W. Yang , Daniel S. Zisook

Embedding algorithms are increasingly used to represent clinical concepts in healthcare for improving machine learning tasks such as clinical phenotyping and disease prediction. Recent studies have adapted state-of-the-art bidirectional…

Machine Learning · Computer Science 2021-12-07 Chao Pang , Xinzhuo Jiang , Krishna S Kalluri , Matthew Spotnitz , RuiJun Chen , Adler Perotte , Karthik Natarajan

Large Language Models (LLMs) excel in Natural Language Processing (NLP) tasks, but they often propagate biases embedded in their training data, which is potentially impactful in sensitive domains like healthcare. While existing benchmarks…

Computation and Language · Computer Science 2026-03-11 Trung Hieu Ngo , Adrien Bazoge , Solen Quiniou , Pierre-Antoine Gourraud , Emmanuel Morin

Social determinants of health (SDOH) play a critical role in Type 2 Diabetes (T2D) management but are often absent from electronic health records and risk prediction models. Most individual-level SDOH data is collected through structured…

Computation and Language · Computer Science 2026-01-21 Sasha Ronaghi , Prerit Choudhary , David H Rehkopf , Bryant Lin

Background: Social determinants of health (SDoH) play a crucial role in influencing health outcomes, accounting for nearly 50% of modifiable health factors and bringing to light critical disparities among disadvantaged groups. Despite the…

In recent years, with the growing amount of biomedical documents, coupled with advancement in natural language processing algorithms, the research on biomedical named entity recognition (BioNER) has increased exponentially. However, BioNER…

Computation and Language · Computer Science 2020-09-22 Usman Naseem , Matloob Khushi , Vinay Reddy , Sakthivel Rajendran , Imran Razzak , Jinman Kim