Related papers: How a simple chloroplast psbA gene mutation change…
Agriculture is one of the oldest forms of technology on Earth. The cultivation of plants requires a terrestrial planet with active hydrological and carbon cycles and depends on the availability of nitrogen in soil. The technological…
In the context of multistability driven diseases, like cancer, spatiotemporal plasticity plays a significant role to achieve a spectrum of phenotypic variations. The interplay between gene regulatory networks and environmental factors, such…
Plants have developed intricate mechanisms to adapt to changing light conditions. Besides photo- and helio- tropism -- the differential growth towards light and the diurnal motion with respect to sunlight -- chloroplast motion acts as a…
Dramatic rise of mutators has been found to accompany adaptation of bacteria in response to many kinds of stress. Two views on the evolutionary origin of this phenomenon emerged: the pleiotropic hypothesis positing that it is a byproduct of…
Adaptive therapy (AT) is designed to postpone the emergence of drug resistance by exploiting evolutionary competition among tumor subclones. Most mathematical models of AT assume a binary population structure of drug-sensitive and…
Antimicrobial resistance is an emerging global health crisis that is undermining advances in modern medicine and, if unmitigated, threatens to kill 10 million people per year worldwide by 2050. Research over the last decade has demonstrated…
A strategy based on photo sequencing batch operation was used to select cyanobacteria over unsettled green algae in a wastewater treatment system, evaluating for the first time the effect of hydraulic regimes on nutritional dynamics and…
With the increase in world population, food resources have to be modified to be more productive, resistive, and reliable. Wheat is one of the most important food resources in the world, mainly because of the variety of wheat-based products.…
Vegetation can modify the planetary surface albedo via the Charney mechanism, as plants are usually darker than the bare surface of the continents. We updated ESTM (Earth-like Surface Temperature Model) to incorporate the presence,…
Anthropogenic changes of the biota and human hyper-dominance are modulating the evolution of life on our planet. Humankind has spread worldwide supported by cultural and technological knowledge, and has already modified uncountable…
A major issue in the modelling of weed resistance to herbicide lies in effectively handling the wild dynamics, that is, the allele frequency prior to the herbicide application, and in particular when starting to use the herbicide. The wild…
The evolutionary origins of structural features in reconstructed gene-regulatory networks (GRNs) remain poorly understood, especially given the random aspects of gene expression. Here, we extend a classical model of GRN evolution to allow a…
Main goal: The aim of this note is to propose a modeling approach for assessing the effectiveness of pest biocontrol by natural enemies in diversified agricultural landscapes including several pesticide-based management strategies. Our…
The evolution of microbial and viral organisms often generates clonal interference, a mode of competition between genetic clades within a population. In this paper, we show that interference strongly constrains the genetic and phenotypic…
Chloroplasts regulate their growth to optimize photosynthesis. Quantitative data shows that the ratio of total chloroplast area to mesophyll cell area is constant across different cells within a single species, and also across species.…
We study a genetic regulatory network model developed to demonstrate that genetic robustness can evolve through stabilizing selection for optimal phenotypes. We report preliminary results on whether such selection could result in a…
We propose a model to describe the adaptation of a phenotypically structured population in a $H$-patch environment connected by migration, with each patch associated with a different phenotypic optimum, and we perform a rigorous…
One of the most challenging problems in microbiology is to understand how a small fraction of microbes that resists killing by antibiotics can emerge in a population of genetically identical cells, the phenomenon known as persistence or…
High-density planting is a widely adopted strategy to enhance maize productivity, yet it introduces challenges such as increased interplant competition and shading, which can limit light capture and overall yield potential. In response,…
Sagan et al. (1993) used the Galileo space probe data and first principles to find evidence of life on Earth. Here we ask whether Sagan et al. (1993) could also have detected whether life on Earth had three-dimensional structure, based on…