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Related papers: Persistent Dirac for molecular representation

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We extend the modeling framework of port-Hamiltonian descriptor systems to include under- and over-determined systems and arbitrary differentiable Hamiltonian functions. This structure is associated with a Dirac structure that encloses its…

Optimization and Control · Mathematics 2019-03-26 Volker Mehrmann , Riccardo Morandin

Molecular representation learning is pivotal for various molecular property prediction tasks related to drug discovery. Robust and accurate benchmarks are essential for refining and validating current methods. Existing molecular property…

Chemical Physics · Physics 2024-06-27 Shikun Feng , Jiaxin Zheng , Yinjun Jia , Yanwen Huang , Fengfeng Zhou , Wei-Ying Ma , Yanyan Lan

Molecular graphs generally contain subgraphs (known as groups) that are identifiable and significant in composition, functionality, geometry, etc. Flat latent representations (node embeddings or graph embeddings) fail to represent, and…

Machine Learning · Computer Science 2019-04-05 Daniel T. Chang

Clustering performs an essential role in many real world applications, such as market research, pattern recognition, data analysis, and image processing. However, due to the high dimensionality of the input feature values, the data being…

Machine Learning · Computer Science 2021-02-16 Si Lu , Ruisi Li

Topological Data Analysis (TDA) provides tools to describe the shape of data, but integrating topological features into deep learning pipelines remains challenging, especially when preserving local geometric structure rather than…

Machine Learning · Computer Science 2026-04-21 Elena Xinyi Wang , Arnur Nigmetov , Dmitriy Morozov

A suitable feature representation that can both preserve the data intrinsic information and reduce data complexity and dimensionality is key to the performance of machine learning models. Deeply rooted in algebraic topology, persistent…

Algebraic Topology · Mathematics 2018-11-02 Chi Seng Pun , Kelin Xia , Si Xian Lee

We use a continuous mesoscopic model to address the yielding properties of plastic composites, formed by a host material and inclusions with different elastic and/or plastic properties. We investigate the flow properties of the composed…

Statistical Mechanics · Physics 2020-05-06 E. A. Jagla

Topological Data Analysis (TDA) has emerged as a powerful framework for extracting robust, multiscale, and interpretable features from complex molecular data for artificial intelligence (AI) modeling and topological deep learning (TDL).…

Biomolecules · Quantitative Biology 2025-09-23 JunJie Wee , Jian Jiang

Recent research in molecular discovery has primarily been devoted to small, drug-like molecules, leaving many similarly important applications in material design without adequate technology. These applications often rely on more complex…

Port-Hamiltonian systems provide an energy-based formulation with a model class that is closed under structure preserving interconnection. For continuous-time systems these interconnections are constructed by geometric objects called Dirac…

Optimization and Control · Mathematics 2023-08-21 Karim Cherifi , Hannes Gernandt , Dorothea Hinsen , Volker Mehrmann

We review some recently published methods to represent atomic neighbourhood environments, and analyse their relative merits in terms of their faithfulness and suitability for fitting potential energy surfaces. The crucial properties that…

Computational Physics · Physics 2015-06-11 Albert P. Bartók , Risi Kondor , Gábor Csányi

We show that a wide class of quantum systems with translational invariance can host dispersionless, soliton-like, wave packets. We focus on the setting where the effective, two-dimensional Hamiltonian acquires the form of the Dirac…

Mesoscale and Nanoscale Physics · Physics 2017-06-13 Vit Jakubsky , Matej Tusek

Discrete gradient methods are a powerful tool for the time discretization of dynamical systems, since they are structure-preserving regardless of the form of the total energy. In this work, we discuss the application of discrete gradient…

Numerical Analysis · Mathematics 2026-01-06 Philipp L. Kinon , Riccardo Morandin , Philipp Schulze

In the presence of a non-vanishing chemical potential the eigenvalues of the Dirac operator become complex. We calculate spectral correlation functions of complex eigenvalues using a random matrix model approach. Our results apply to…

High Energy Physics - Theory · Physics 2009-11-07 G. Akemann

Molecular property prediction constitutes a cornerstone of drug discovery and materials science, necessitating models capable of disentangling complex structure-property relationships across diverse molecular modalities. Existing approaches…

Machine Learning · Computer Science 2026-03-24 Long Xu , Junping Guo , Jianbo Zhao , Jianbo Lu , Yuzhong Peng

Potential algebras can be used effectively in the analysis of the quantum systems. In the article, we focus on the systems described by a separable, 2x2 matrix Hamiltonian of the first order in derivatives. We find integrals of motion of…

Mathematical Physics · Physics 2015-06-11 Vit Jakubsky

In this paper, we find a polynomial-type Jost solution of a self-adjoint matrix-valued discrete Dirac system. Then we investigate analytical properties and asymptotic behavior of this Jost solution. Using the Weyl compact perturbation…

Functional Analysis · Mathematics 2015-10-09 Yelda Aygar , Elgiz Bairamov , Seyhmus Yardımcı

We consider continuous Dirac operators defined on $\mathbf{R}^d$, $d\in\{1,2,3\}$, together with various discrete versions of them. Both forward-backward and symmetric finite differences are used as approximations to partial derivatives. We…

Mathematical Physics · Physics 2023-07-19 Horia D. Cornean , Henrik Garde , Arne Jensen

In the $\varepsilon$-regime of chiral perturbation theory the spectral correlations of the Euclidean QCD Dirac operator close to the origin can be computed using random matrix theory. To incorporate the effect of temperature, a random…

Mathematical Physics · Physics 2022-01-05 Gernot Akemann , Tim R. Würfel

Random matrix theory is a powerful way to describe universal correlations of eigenvalues of complex systems. It also may serve as a schematic model for disorder in quantum systems. In this review, we discuss both types of applications of…

High Energy Physics - Phenomenology · Physics 2009-10-31 J. J. M. Verbaarschot , T. Wettig