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Experimental control and detection of atoms and molecules often rely on optical transitions between different electronic states. In many cases, substructure such as hyperfine or spin-rotation structure leads to the need for multiple optical…

Atomic Physics · Physics 2021-05-26 Connor M. Holland , Yukai Lu , Lawrence W. Cheuk

To assist in the development of machine learning methods for automated classification of spectroscopic data, we have generated a universal synthetic dataset that can be used for model validation. This dataset contains artificial spectra…

Machine Learning · Computer Science 2022-06-15 Jan Schuetzke , Nathan J. Szymanski , Markus Reischl

We propose to develop mean field theory in combination with Glauber algorithm, to model and interpret protein dynamics and structure formation in small to wide angle x-ray scattering (S/WAXS) experiments. We develop the methodology by…

Biomolecules · Quantitative Biology 2017-12-20 Alexandr Nasedkin , Jan Davidsson , Antti J. Niemi , Xubiao Peng

Most detector systems used for positron emission particle tracking (PEPT) are very expensive due to the use of inorganic plastic scintillators combined with a high number of readout electronic channels. This work aims to reduce the overall…

An exploit of the Sequential Importance Sampling (SIS) algorithm using Differential Algebra (DA) techniques is derived to develop an efficient particle filter. The filter creates an original kind of particles, called scout particles, that…

Information Theory · Computer Science 2024-08-21 Simone Servadio

We report a new version of spectral phase interferometry for direct electric field reconstruction (SPIDER), which enables consistency checking through the simultaneous acquisition of multiple shears and offers a simple and precise…

Optics · Physics 2019-03-27 Tobias Witting , Dane R. Austin , Ian A. Walmsley

The following thesis presents research which constitutes the first steps towards the construction of a novel SiFi-CC detector intended for real-time monitoring of proton therapy. The detector construction will be based on inorganic…

Instrumentation and Detectors · Physics 2023-06-21 Katarzyna Rusiecka

Compact photonic elements that control both the diffraction and interference of light offer superior performance at ultra-compact dimensions. Unlike conventional optical structures, these diffractive optical elements can provide…

Optics · Physics 2024-06-19 Alim Yolalmaz , Emre Yüce

The major advantage of proton therapy over conventional radiotherapy is the dose deposition pattern, enabling precise coverage of the tumour volume while sparing nearby healthy tissues. However, accurate control of the proton beam range…

Medical Physics · Physics 2025-04-01 Magdalena Kołodziej

Miniaturized spectrometers employing chip solutions are essential for a wide range of applications, such as wearable health monitoring, biochemical sensing, and portable optical coherence tomography. However, the development of integrated…

Optics · Physics 2025-05-22 Wenzhang Tian , Hao Chen , Mingyuan Zhang , Zengqi Chen , Yeyu Tong

A theoretical framework is developed to estimate the optimal binning of X-ray spectra. We derived expressions for the optimal bin size for model spectra as well as for observed data using different levels of sophistication. It is shown that…

Instrumentation and Methods for Astrophysics · Physics 2016-03-09 J. S. Kaastra , J. A. M. Bleeker

Implementing large instances of quantum algorithms requires the processing of many quantum information carriers in a hardware platform that supports the integration of different components. While established semiconductor fabrication…

In order to focus hard X- and gamma-rays it is possible to make use of a Laue lens as a concentrator. With this optical tool it would be possible to improve the detection of radiation for several applications, spanning from the observation…

Optics · Physics 2014-10-08 Riccardo Camattari , Vincenzo Guidi

The next generation of adaptive optics (AO) systems will require tomographic reconstruction techniques to map the optical refractive index fluctuations, generated by the atmospheric turbulence, along the line of sight to the astronomical…

Instrumentation and Methods for Astrophysics · Physics 2014-01-07 H. W. Shepherd , J. Osborn , R. W. Wilson , T. Butterley , R. Avila , V. S. Dhillon , T. J. Morris

Motivation: Microarray data has been recently been shown to be efficacious in distinguishing closely related cell types that often appear in the diagnosis of cancer. It is useful to determine the minimum number of genes needed to do such a…

Biological Physics · Physics 2007-05-23 J. M. Deutsch

Computational spectroscopic instruments with Broadband Encoding Stochastic (BEST) filters allow the reconstruction of the spectrum at high precision with only a few filters. However, conventional design manners of BEST filters are often…

Instrumentation and Detectors · Physics 2020-12-18 Hongya Song , Yaoguang Ma , Yubing Han , Weidong Shen , Wenyi Zhang , Yanghui Li , Xu Liu , Yifan Peng , Xiang Hao

We present a user-friendly and versatile tool for laser frequency stabilization. Its main focus is spectroscopy locking, but the software is suitable for lock-in techniques in general as well as bare PID operation. Besides allowing for…

Instrumentation and Detectors · Physics 2022-06-16 Benjamin Wiegand , Bastian Leykauf , Robert Jördens , Markus Krutzik

X-ray emission spectroscopy is a well-established technique used to study continuum lowering in dense plasmas. It relies on accurate atomic physics models to robustly reproduce high-resolution emission spectra, and depends on our ability to…

Plasma Physics · Physics 2020-01-22 M. F. Kasim , J. S. Wark , S. M. Vinko

Line Intensity Mapping (LIM) is a new observational technique that uses low-resolution observations of line emission to efficiently trace the large-scale structure of the Universe out to high redshift. Common mm/sub-mm emission lines are…

Polarization-based filtering in fiber lasers is well-known to enable spectral tunability and a wide range of dynamical operating states. This effect is rarely exploited in practical systems, however, because optimization of cavity…

Optics · Physics 2017-10-11 R. I. Woodward , E. J. R. Kelleher