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This paper extends my research applying statistical decision theory to treatment choice with sample data, using maximum regret to evaluate the performance of treatment rules. The specific new contribution is to study as-if optimization…

Econometrics · Economics 2021-10-05 Charles F. Manski

Personalized decision making targets the behavior of a specific individual, while population-based decision making concerns a sub-population resembling that individual. This paper clarifies the distinction between the two and explains why…

Artificial Intelligence · Computer Science 2022-08-23 Scott Mueller , Judea Pearl

This paper proposes a novel approach for constructing effective personalized policies when the observed data lacks counter-factual information, is biased and possesses many features. The approach is applicable in a wide variety of settings…

Machine Learning · Statistics 2018-07-11 Onur Atan , William R. Zame , Qiaojun Feng , Mihaela van der Schaar

In our original article (Sarvet & Stensrud, 2024), we examine twin definitions of "harm" in personalized medicine: one based on predictions of individuals' unmeasurable response types (counterfactual harm), and another based solely on the…

Applications · Statistics 2024-03-25 Aaron L. Sarvet , Mats J. Stensrud

The problem of individualization is recognized as crucial in almost every field. Identifying causes of effects in specific events is likewise essential for accurate decision making. However, such estimates invoke counterfactual…

Methodology · Statistics 2021-05-04 Scott Mueller , Ang Li , Judea Pearl

Identifying who should be treated is a central question in economics. There are two competing approaches to targeting - paternalistic and autonomous. In the paternalistic approach, policymakers optimally target the policy given observable…

Precision medicine has the potential to tailor treatment decisions to individual patients using machine learning (ML) and artificial intelligence (AI), but it faces significant challenges due to complex biases in clinical observational data…

Machine Learning · Computer Science 2024-11-26 Michael Vollenweider , Manuel Schürch , Chiara Rohrer , Gabriele Gut , Michael Krauthammer , Andreas Wicki

Differentially private statistical estimation has seen a flurry of developments over the last several years. Study has been divided into two schools of thought, focusing on empirical statistics versus population statistics. We suggest that…

Machine Learning · Statistics 2020-05-04 Gautam Kamath , Jonathan Ullman

Doctors use statistics to advance medical knowledge; we use a medical analogy to introduce statistical inference "from scratch" and to highlight an improvement. Your doctor, perhaps implicitly, predicts the effectiveness of a treatment for…

Methodology · Statistics 2015-11-29 Keli Liu , Xiao-Li Meng

When a new treatment is considered for use, whether a pharmaceutical drug or a search engine ranking algorithm, a typical question that arises is, will its performance exceed that of the current treatment? The conventional way to answer…

Machine Learning · Computer Science 2016-10-27 Nir Rosenfeld , Yishay Mansour , Elad Yom-Tov

Clinical trials usually target average treatment effects, but treatment decisions are made for individuals. This tension motivates a common criticism of evidence-based medicine: a treatment that is beneficial on average may be inappropriate…

Applications · Statistics 2026-05-29 Zach Shahn , Mats Stensrud

Personalizing interventions and treatments is a necessity for optimal medical care. Recent advances in computing, such as personal electronic devices, have made it easier than ever to collect and utilize vast amounts of personal data on…

Computers and Society · Computer Science 2017-11-16 Orianna DeMasi , Benjamin Recht

Can stated preferences help in counterfactual analyses of actual choice? This research proposes a novel approach to researchers who have access to both stated choices in hypothetical scenarios and actual choices. The key idea is to use…

Econometrics · Economics 2023-07-27 Romuald Meango

We consider the problem of learning fair decision systems in complex scenarios in which a sensitive attribute might affect the decision along both fair and unfair pathways. We introduce a causal approach to disregard effects along unfair…

Machine Learning · Statistics 2018-02-23 Silvia Chiappa , Thomas P. S. Gillam

Counterfactual explanations are increasingly proposed as interpretable mechanisms to achieve algorithmic recourse. However, current counterfactual techniques for time series classification are predominantly designed with static data…

Machine Learning · Computer Science 2025-12-17 Emmanuel C. Chukwu , Rianne M. Schouten , Monique Tabak , Mykola Pechenizkiy

Estimating an individual's potential outcomes under counterfactual treatments is a challenging task for traditional causal inference and supervised learning approaches when the outcome is high-dimensional (e.g. gene expressions, impulse…

Machine Learning · Statistics 2025-02-13 Yulun Wu , Layne C. Price , Zichen Wang , Vassilis N. Ioannidis , Robert A. Barton , George Karypis

The authors discuss their experience applying differential privacy with a complex data set with the goal of enabling standard approaches to statistical data analysis. They highlight lessons learned and roadblocks encountered, distilling…

Cryptography and Security · Computer Science 2023-10-02 Joshua Snoke , Claire McKay Bowen , Aaron R. Williams , Andrés F. Barrientos

Experimental work regularly finds that individual choices are not deterministically rationalized by well-defined preferences. Nonetheless, recent work shows that data collected from many individuals can be stochastically rationalized by a…

Theoretical Economics · Economics 2021-10-22 Changkuk Im , John Rehbeck

Recommender systems are gaining increasing and critical impacts on human and society since a growing number of users use them for information seeking and decision making. Therefore, it is crucial to address the potential unfairness problems…

Information Retrieval · Computer Science 2021-11-08 Yunqi Li , Hanxiong Chen , Shuyuan Xu , Yingqiang Ge , Yongfeng Zhang

This paper motivates the study of decision theory as necessary for aligning smarter-than-human artificial systems with human interests. We discuss the shortcomings of two standard formulations of decision theory, and demonstrate that they…

Artificial Intelligence · Computer Science 2015-07-09 Nate Soares , Benja Fallenstein
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