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Mixup style data augmentation algorithms have been widely adopted in various tasks as implicit network regularization on representation learning to improve model generalization, which can be achieved by a linear interpolation of labeled…

Computer Vision and Pattern Recognition · Computer Science 2023-05-31 Kangjun Liu , Ke Chen , Lihua Guo , Yaowei Wang , Kui Jia

Existing pretraining data mixing methods for large language models (LLMs) typically follow a domain-wise methodology, a top-down process that first determines domain weights and then performs uniform data sampling across each domain.…

Computation and Language · Computer Science 2025-03-04 Xiangyu Xi , Deyang Kong , Jian Yang , Jiawei Yang , Zhengyu Chen , Wei Wang , Jingang Wang , Xunliang Cai , Shikun Zhang , Wei Ye

The classification of glomerular lesions is a routine and essential task in renal pathology. Recently, machine learning approaches, especially deep learning algorithms, have been used to perform computer-aided lesion characterization of…

Quantitative Methods · Quantitative Biology 2021-01-20 Yuzhe Lu , Haichun Yang , Zheyu Zhu , Ruining Deng , Agnes B. Fogo , Yuankai Huo

Due to its superior efficiency in utilizing annotations and addressing gigapixel-sized images, multiple instance learning (MIL) has shown great promise as a framework for whole slide image (WSI) classification in digital pathology…

Quantitative Methods · Quantitative Biology 2023-07-14 Qiehe Sun , Jiawen Li , Jin Xu , Junru Cheng , Tian Guan , Yonghong He

Mixup has become a popular augmentation strategy for image classification, yet its naive pixel-wise interpolation often produces unrealistic images that can hinder learning, particularly in high-stakes medical applications. We propose…

Computer Vision and Pattern Recognition · Computer Science 2025-09-26 Hugo Carlesso , Maria Eliza Patulea , Moncef Garouani , Radu Tudor Ionescu , Josiane Mothe

While deep neural networks have achieved remarkable performance, data augmentation has emerged as a crucial strategy to mitigate overfitting and enhance network performance. These techniques hold particular significance in industrial…

Computer Vision and Pattern Recognition · Computer Science 2024-01-19 Hyungmin Kim , Donghun Kim , Pyunghwan Ahn , Sungho Suh , Hansang Cho , Junmo Kim

Text-to-image (T2I) generative models have recently emerged as a powerful tool, enabling the creation of photo-realistic images and giving rise to a multitude of applications. However, the effective integration of T2I models into…

Computer Vision and Pattern Recognition · Computer Science 2024-03-29 Zhicai Wang , Longhui Wei , Tan Wang , Heyu Chen , Yanbin Hao , Xiang Wang , Xiangnan He , Qi Tian

In this study, we propose a novel data augmentation method that introduces the concept of CutMix into the generation process of diffusion models, thereby exploiting both the ability of diffusion models to generate natural and…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 Shumpei Takezaki , Ryoma Bise , Shinnosuke Matsuo

Histopathological images are essential for medical diagnosis and treatment planning, but interpreting them accurately using machine learning can be challenging due to variations in tissue preparation, staining and imaging protocols. Domain…

Computer Vision and Pattern Recognition · Computer Science 2023-11-01 Vaibhav Khamankar , Sutanu Bera , Saumik Bhattacharya , Debashis Sen , Prabir Kumar Biswas

In the context of continual learning, acquiring new knowledge while maintaining previous knowledge presents a significant challenge. Existing methods often use experience replay techniques that store a small portion of previous task data…

Machine Learning · Computer Science 2025-12-24 Minsu Kim , Seong-Hyeon Hwang , Steven Euijong Whang

Deep learning models have revolutionized the field of medical image analysis, due to their outstanding performances. However, they are sensitive to spurious correlations, often taking advantage of dataset bias to improve results for…

Computer Vision and Pattern Recognition · Computer Science 2024-05-06 Diogo J. Araújo , M. Rita Verdelho , Alceu Bissoto , Jacinto C. Nascimento , Carlos Santiago , Catarina Barata

Digital pathology archives increasingly contain multiple whole-slide images (WSIs) per case, capturing spatially distinct tumour regions and reflecting intrinsic morphological heterogeneity. However, most existing approaches rely on a…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Zahra Rahimi Afzal , Wataru Uegami , Saghir Alfasly , Saba Yasir , Judy C. Boughey , Matthew P. Goetz , Krishna R. Kalari , H. R. Tizhoosh

In recent years, several unsupervised cell segmentation methods have been presented, trying to omit the requirement of laborious pixel-level annotations for the training of a cell segmentation model. Most if not all of these methods handle…

Computer Vision and Pattern Recognition · Computer Science 2023-12-04 Mehdi Naouar , Gabriel Kalweit , Anusha Klett , Yannick Vogt , Paula Silvestrini , Diana Laura Infante Ramirez , Roland Mertelsmann , Joschka Boedecker , Maria Kalweit

Pathological image analysis is an important process for detecting abnormalities such as cancer from cell images. However, since the image size is generally very large, the cost of providing detailed annotations is high, which makes it…

Computer Vision and Pattern Recognition · Computer Science 2023-04-10 Shusuke Takahama , Yusuke Kurose , Yusuke Mukuta , Hiroyuki Abe , Akihiko Yoshizawa , Tetsuo Ushiku , Masashi Fukayama , Masanobu Kitagawa , Masaru Kitsuregawa , Tatsuya Harada

Multiple instance learning (MIL) is a promising approach for weakly supervised classification in pathology using whole slide images (WSIs). However, conventional MIL methods such as Attention-Based Deep Multiple Instance Learning (ABMIL)…

Image and Video Processing · Electrical Eng. & Systems 2025-04-28 Hassan Keshvarikhojasteh , Mihail Tifrea , Sibylle Hess , Josien P. W. Pluim , Mitko Veta

Advanced data augmentation strategies have widely been studied to improve the generalization ability of deep learning models. Regional dropout is one of the popular solutions that guides the model to focus on less discriminative parts by…

Machine Learning · Computer Science 2021-07-28 A. F. M. Shahab Uddin , Mst. Sirazam Monira , Wheemyung Shin , TaeChoong Chung , Sung-Ho Bae

Computational pathology, integrating computational methods and digital imaging, has shown to be effective in advancing disease diagnosis and prognosis. In recent years, the development of machine learning and deep learning has greatly…

Image and Video Processing · Electrical Eng. & Systems 2025-02-25 Jiamu Wang , Chang-Su Kim , Jin Tae Kwak

Data augmentation is a widely used technique in many machine learning tasks, such as image classification, to virtually enlarge the training dataset size and avoid overfitting. Traditional data augmentation techniques for image…

Machine Learning · Computer Science 2018-04-12 Hiroshi Inoue

Differences in staining and imaging procedures can cause significant color variations in histopathology images, leading to poor generalization when deploying deep-learning models trained from a different data source. Various color…

Despite continued advancement in recent years, deep neural networks still rely on large amounts of training data to avoid overfitting. However, labeled training data for real-world applications such as healthcare is limited and difficult to…