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Parkinson's disease (PD), a neurodegenerative disorder, often manifests as speech and voice dysfunction. While utilizing voice data for PD detection has great potential in clinical applications, the widely used deep learning models…

Machine Learning · Computer Science 2023-09-26 Yicheng Wang , Xiaotian Han , Leisheng Yu , Na Zou

Parkinson's disease (PD) is a progressive disorder in which symptom burden and functional impairment evolve over time, making severity staging essential for clinical monitoring and treatment planning. However, many computational studies…

Machine Learning · Computer Science 2026-04-21 Md Mezbahul Islam , John Michael Templeton , Christian Poellabauer , Ananda Mohan Mondal

Adaptive deep brain stimulation (aDBS) has emerged as a promising treatment for Parkinson disease (PD). In aDBS, a surgically placed electrode sends dynamically altered stimuli to the brain based on neurophysiological feedback: an invasive…

Neurons and Cognition · Quantitative Biology 2025-05-16 Ekaterina Kuzmina , Dmitrii Kriukov , Mikhail Lebedev , Dmitry V. Dylov

This paper deals with a complex acoustic analysis of phonation in patients with Parkinson's disease (PD) with a special focus on estimation of disease progress that is described by 7 different clinical scales ,e. g. Unified Parkinson's…

A large scale computational model of the basal ganglia (BG) network is proposed to describes movement disorder including deep brain stimulation (DBS). The model of this complex network considers four areas of the basal ganglia network: the…

Neurons and Cognition · Quantitative Biology 2021-03-15 Konstantinos Spiliotis , Jens Starke , Denise Franz , Angelika Richter , Rüdiger Köhling

Abnormal gait, its associated falls and complications have high patient morbidity, mortality. Computer vision detects, predicts patient gait abnormalities, assesses fall risk and serves as clinical decision support tool for physicians. This…

Computer Vision and Pattern Recognition · Computer Science 2020-04-07 Jasmin Hundall , Benson A. Babu

Early and accurate detection of Parkinson's disease (PD) is a crucial diagnostic challenge carrying immense clinical significance, for effective treatment regimens and patient management. For instance, a group of subjects termed SWEDD who…

Image and Video Processing · Electrical Eng. & Systems 2025-06-24 R. Prashanth

Parkinson's Disease (PD) significantly impacts driving abilities, often leading to early driving cessation or accidents due to reduced motor control and increasing reaction times. To diminish the impact of these symptoms, we developed PANDA…

Human-Computer Interaction · Computer Science 2025-03-11 Tianyang Wen , Xucheng Zhang , Zhirong Wan , Jing Zhao , Yicheng Zhu , Ning Su , Xiaolan Peng , Jin Huang , Wei Sun , Feng Tian , Franklin Mingzhe Li

Parkinson's disease is the world's fastest-growing neurological disorder. Research to elucidate the mechanisms of Parkinson's disease and automate diagnostics would greatly improve the treatment of patients with Parkinson's disease. Current…

Machine Learning · Computer Science 2024-02-20 Charlie Tran , Kai Shen , Kang Liu , Akshay Ashok , Adolfo Ramirez-Zamora , Jinghua Chen , Yulin Li , Ruogu Fang

This paper considers a representation learning strategy to model speech signals from patients with Parkinson's disease and cleft lip and palate. In particular, it compares different parametrized representation types such as wideband and…

Audio and Speech Processing · Electrical Eng. & Systems 2022-09-20 Gabriel Figueiredo Miller , Juan Camilo Vásquez-Correa , Juan Rafael Orozco-Arroyave , Elmar Nöth

Identification of risk factors associated with falls in people with Parkinson's Disease (PD) is important due to their high risk of falling. In this study, various ways of utilizing the Unified Parkinson's Disease Rating Scale (UPDRS) were…

Applications · Statistics 2019-10-04 Sarini Abdullah , Nicole White , James McGree , Kerrie Mengersen , Graham Kerr

Parkinson's disease is a neurodegenerative disorder that can be very tricky to diagnose and treat. Such early symptoms can include tremors, wheezy breathing, and changes in voice quality as critical indicators of neural damage. Notably,…

Sound · Computer Science 2025-11-20 Abishek Karthik , Pandiyaraju V , Dominic Savio M , Rohit Swaminathan S

Interpreting the environmental, behavioural and psychological data from in-home sensory observations and measurements can provide valuable insights into the health and well-being of individuals. Presents of neuropsychiatric and…

Signal Processing · Electrical Eng. & Systems 2021-05-24 Roonak Rezvani , Samaneh Kouchaki , Ramin Nilforooshan , David J. Sharp , Payam Barnaghi

Parkinson's disease is easy to diagnose when it is advanced, but it is very difficult to diagnose in its early stages. Early diagnosis is essential to be able to treat the symptoms. It impacts on daily activities and reduces the quality of…

Omics data analysis is crucial for studying complex diseases, but its high dimensionality and heterogeneity challenge classical statistical and machine learning methods. Graph neural networks have emerged as promising alternatives, yet the…

Alzheimer's disease (AD) is known as one of the major causes of dementia and is characterized by slow progression over several years, with no treatments or available medicines. In this regard, there have been efforts to identify the risk of…

Computer Vision and Pattern Recognition · Computer Science 2020-08-28 Wonsik Jung , Eunji Jun , Heung-Il Suk

We present InceptoFormer, a multi-signal neural framework designed for Parkinson's Disease (PD) severity evaluation via gait dynamics analysis. Our architecture introduces a 1D adaptation of the Inception model, which we refer to as…

Computer Vision and Pattern Recognition · Computer Science 2025-08-07 Safwen Naimi , Arij Said , Wassim Bouachir , Guillaume-Alexandre Bilodeau

In recent years, sensors from smart consumer devices have shown great diagnostic potential in movement disorders. In this context, data modalities such as electronic questionnaires, hand movement and voice captures have successfully…

Machine Learning · Computer Science 2022-05-13 Catharina Marie van Alen , Alexander Brenner , Tobias Warnecke , Julian Varghese

Parkinson's disease is a widespread neurodegenerative condition necessitating early diagnosis for effective intervention. This paper introduces an innovative method for diagnosing Parkinson's disease through the analysis of human EEG…

Signal Processing · Electrical Eng. & Systems 2024-05-03 Maryam Allahbakhshi , Aylar Sadri , Seyed Omid Shahdi

Eye-tracking is an accessible and non-invasive technology that provides information about a subject's motor and cognitive abilities. As such, it has proven to be a valuable resource in the study of neurodegenerative diseases such as…

Machine Learning · Computer Science 2023-11-29 Gonzalo Uribarri , Simon Ekman von Huth , Josefine Waldthaler , Per Svenningsson , Erik Fransén
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