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This paper presents a novel density estimation method for anomaly detection using density matrices (a powerful mathematical formalism from quantum mechanics) and Fourier features. The method can be seen as an efficient approximation of…

Machine Learning · Computer Science 2022-10-27 Oscar Bustos-Brinez , Joseph Gallego-Mejia , Fabio A. González

Understanding the dynamic behavior of biomolecules is fundamental to elucidating biological function and facilitating drug discovery. While Molecular Dynamics (MD) simulations provide a rigorous physical basis for studying these dynamics,…

Biomolecules · Quantitative Biology 2026-03-19 Liang Shi , Jiarui Lu , Junqi Liu , Chence Shi , Zhi Yang , Jian Tang

Chemical kinetics mechanisms are essential for understanding, analyzing, and simulating complex combustion phenomena. In this study, a Neural Ordinary Differential Equation (Neural ODE) framework is employed to optimize kinetics parameters…

Chemical Physics · Physics 2022-09-07 Xingyu Su , Weiqi Ji , Jian An , Zhuyin Ren , Sili Deng , Chung K. Law

The scarcity of high-quality public log datasets has become a critical bottleneck in advancing log-based anomaly detection techniques. Current datasets exhibit three fundamental limitations: (1) incomplete event coverage, (2) artificial…

Software Engineering · Computer Science 2025-04-17 Xinyu Li , Yingtong Huo , Chenxi Mao , Shiwen Shan , Yuxin Su , Dan Li , Zibin Zheng

Kernel-based methods exhibit well-documented performance in various nonlinear learning tasks. Most of them rely on a preselected kernel, whose prudent choice presumes task-specific prior information. Especially when the latter is not…

Machine Learning · Statistics 2018-12-31 Yanning Shen , Tianyi Chen , Georgios B. Giannakis

Formal language techniques have been used in the past to study autonomous dynamical systems. However, for controlled systems, new features are needed to distinguish between information generated by the system and input control. We show how…

Computation and Language · Computer Science 2007-05-23 J. F. Martins , J. A. Dente , A. J. Pires , R. Vilela Mendes

Automating machine learning has achieved remarkable technological developments in recent years, and building an automated machine learning pipeline is now an essential task. The model ensemble is the technique of combining multiple models…

Machine Learning · Computer Science 2022-07-21 Yunpu Zhao , Rui Zhang , Xiaqing Li

Kinetic parameters such as the turnover number ($k_{cat}$) and Michaelis constant ($K_{\mathrm{M}}$) are essential for modelling enzymatic activity but experimental data remains limited in scale and diversity. Previous methods for…

Quantitative Methods · Quantitative Biology 2025-07-22 Saleh Alwer , Ronan Fleming

Agentic Retrieval-Augmented Generation (RAG) systems enhance Large Language Models (LLMs) by enabling dynamic, multi-step reasoning and information retrieval. However, these systems often exhibit sub-optimal search behaviors like…

Computation and Language · Computer Science 2025-10-10 Peilin Wu , Mian Zhang , Xinlu Zhang , Xinya Du , Zhiyu Zoey Chen

The enzyme turnover rate is a fundamental parameter in enzyme kinetics, reflecting the catalytic efficiency of enzymes. However, enzyme turnover rates remain scarce across most organisms due to the high cost and complexity of experimental…

Machine Learning · Computer Science 2025-09-16 Bozhen Hu , Cheng Tan , Siyuan Li , Jiangbin Zheng , Sizhe Qiu , Jun Xia , Stan Z. Li

In this paper, we present a novel diagnostic framework that integrates Knowledge Graphs (KGs) and Large Language Models (LLMs) to support system diagnostics in high-reliability systems such as nuclear power plants. Traditional diagnostic…

Artificial Intelligence · Computer Science 2025-09-01 Saman Marandi , Yu-Shu Hu , Mohammad Modarres

Building efficient neural network architectures can be a time-consuming task requiring extensive expert knowledge. This task becomes particularly challenging for edge devices because one has to consider parameters such as power consumption…

Machine Learning · Computer Science 2024-02-29 Md Hafizur Rahman , Prabuddha Chakraborty

Despite the advancements in learning governing differential equations from observations of dynamical systems, data-driven methods are often unaware of fundamental physical laws, such as frame invariance. As a result, these algorithms may…

Machine Learning · Computer Science 2024-11-06 Jianke Yang , Wang Rao , Nima Dehmamy , Robin Walters , Rose Yu

This paper presents Automatic Algorithm Discoverer (AAD), an evolutionary framework for synthesizing programs of high complexity. To guide evolution, prior evolutionary algorithms have depended on fitness (objective) functions, which are…

Neural and Evolutionary Computing · Computer Science 2019-04-08 Ruchira Sasanka , Konstantinos Krommydas

Generalizable articulated object manipulation is essential for home-assistant robots. Recent efforts focus on imitation learning from demonstrations or reinforcement learning in simulation, however, due to the prohibitive costs of…

Robotics · Computer Science 2024-02-22 Wenke Xia , Dong Wang , Xincheng Pang , Zhigang Wang , Bin Zhao , Di Hu , Xuelong Li

In recent years the machine learning techniques have shown a great potential in various problems from a multitude of disciplines, including materials design and drug discovery. The high computational speed on the one hand and the accuracy…

Chemical Physics · Physics 2018-05-09 Konstantin Gubaev , Evgeny V. Podryabinkin , Alexander V. Shapeev

While Multimodal Large Language Models (MLLMs) demonstrate remarkable capabilities across diverse domains, their application to specialized anomaly detection (AD) remains constrained by domain adaptation challenges. Existing Group Relative…

Computer Vision and Pattern Recognition · Computer Science 2025-08-07 Jingyi Liao , Yongyi Su , Rong-Cheng Tu , Zhao Jin , Wenhao Sun , Yiting Li , Dacheng Tao , Xun Xu , Xulei Yang

Automated material model discovery disrupts the tedious and time-consuming cycle of iteratively calibrating and modifying manually designed models. Non-smooth L1-norm regularization is the backbone of automated model discovery; however, the…

Computational Engineering, Finance, and Science · Computer Science 2025-07-15 Moritz Flaschel , Trevor Hastie , Ellen Kuhl

Engineering molecular systems that exhibit complex behavior requires the design of kinetic barriers. For example, an effective catalytic pathway must have a large barrier when the catalyst is absent. While programming such energy barriers…

Emerging Technologies · Computer Science 2020-01-28 Keenan Breik , Cameron Chalk , David Doty , David Haley , David Soloveichik

We introduce the first Automatically Differentiable Model Updating (ADiMU) framework that finds any history-dependent material model from full-field displacement and global force data (global, indirect discovery) or from strain-stress data…

Numerical Analysis · Mathematics 2025-05-13 Bernardo P. Ferreira , Miguel A. Bessa