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Background: Most acute stroke (AS) patients in the United States are initially evaluated at a primary stroke center (PSC) and a significant proportion requires transfer to a comprehensive stroke center (CSC) for advanced treatment. A CSC…

Quantitative Methods · Quantitative Biology 2022-02-16 Hojun Choi , Ohad Perry , Jane Holl , Shyam Prabhakaran

We present TRACE (Transformer-based Risk Assessment for Clinical Evaluation), a novel method for clinical risk assessment based on clinical data, leveraging the self-attention mechanism for enhanced feature interaction and result…

Computer Vision and Pattern Recognition · Computer Science 2025-05-23 Dionysis Christopoulos , Sotiris Spanos , Valsamis Ntouskos , Konstantinos Karantzalos

Early identification of intensive care patients at risk of in-hospital mortality enables timely intervention and efficient resource allocation. Despite high predictive performance, existing machine learning approaches lack transparency and…

Machine Learning · Computer Science 2025-11-21 Alexander Bakumenko , Janine Hoelscher , Hudson Smith

Deep neural networks are often applied to medical images to automate the problem of medical diagnosis. However, a more clinically relevant question that practitioners usually face is how to predict the future trajectory of a disease.…

Image and Video Processing · Electrical Eng. & Systems 2023-09-20 Huy Hoang Nguyen , Matthew B. Blaschko , Simo Saarakkala , Aleksei Tiulpin

At present, the majority of the proposed Deep Learning (DL) methods provide point predictions without quantifying the models uncertainty. However, a quantification of the reliability of automated image analysis is essential, in particular…

Image and Video Processing · Electrical Eng. & Systems 2020-08-17 Lisa Herzog , Elvis Murina , Oliver Dürr , Susanne Wegener , Beate Sick

In this paper, an automatic algorithm aimed at volumetric segmentation of acute ischemic stroke lesion in non-contrast computed tomography brain 3D images is proposed. Our deep-learning approach is based on the popular 3D U-Net…

Image and Video Processing · Electrical Eng. & Systems 2023-10-31 A. V. Dobshik , S. K. Verbitskiy , I. A. Pestunov , K. M. Sherman , Yu. N. Sinyavskiy , A. A. Tulupov , V. B. Berikov

Deep learning based disease detection and segmentation algorithms promise to improve many clinical processes. However, such algorithms require vast amounts of annotated training data, which are typically not available in the medical context…

Image and Video Processing · Electrical Eng. & Systems 2021-11-02 Moritz Platscher , Jonathan Zopes , Christian Federau

This work presents a novel and promising approach to the clinical management of acute stroke. Using machine learning techniques, our research has succeeded in developing accurate diagnosis and prediction real-time models from hemodynamic…

Signal Processing · Electrical Eng. & Systems 2023-06-09 Luis García-Terriza , José L. Risco-Martín , Gemma Reig Roselló , José L. Ayala

In many medical applications, interpretable models with high prediction performance are sought. Often, those models are required to handle semi-structured data like tabular and image data. We show how to apply deep transformation models…

Predicting outcomes in acute ischemic stroke (AIS) guides clinical decision-making, patient counseling, and resource allocation. Clinical notes contain rich contextual information, but their unstructured nature limits their use in…

A major challenge in stroke research and stroke recovery predictions is the determination of a stroke lesion's extent and its impact on relevant brain systems. Manual segmentation of stroke lesions from 3D magnetic resonance (MR) imaging…

Image and Video Processing · Electrical Eng. & Systems 2023-06-21 Sovesh Mohapatra , Advait Gosai , Anant Shinde , Aleksei Rutkovskii , Sirisha Nouduri , Gottfried Schlaug

Background: Elderly patients with MODS have high risk of death and poor prognosis. The performance of current scoring systems assessing the severity of MODS and its mortality remains unsatisfactory. This study aims to develop an…

Ischemic stroke, caused by cerebral vessel occlusion, presents substantial challenges in medical imaging due to the variability and subtlety of stroke lesions. Magnetic Resonance Imaging (MRI) plays a crucial role in diagnosing and managing…

Image and Video Processing · Electrical Eng. & Systems 2025-01-07 Ashiqur Rahman , Muhammad E. H. Chowdhury , Md Sharjis Ibne Wadud , Rusab Sarmun , Adam Mushtak , Sohaib Bassam Zoghoul , Israa Al-Hashimi

We aim to produce predictive models that are not only accurate, but are also interpretable to human experts. Our models are decision lists, which consist of a series of if...then... statements (e.g., if high blood pressure, then stroke)…

Applications · Statistics 2015-11-06 Benjamin Letham , Cynthia Rudin , Tyler H. McCormick , David Madigan

Ischemic strokes are often caused by large vessel occlusions (LVOs), which can be visualized and diagnosed with Computed Tomography Angiography scans. As time is brain, a fast, accurate and automated diagnosis of these scans is desirable.…

Image and Video Processing · Electrical Eng. & Systems 2022-05-17 Florian Thamm , Oliver Taubmann , Markus Jürgens , Aleksandra Thamm , Felix Denzinger , Leonhard Rist , Hendrik Ditt , Andreas Maier

After admission to emergency department (ED), patients with critical illnesses are transferred to intensive care unit (ICU) due to unexpected clinical deterioration occurrence. Identifying such unplanned ICU transfers is urgently needed for…

Machine Learning · Computer Science 2021-02-10 Chun-An Chou , Qingtao Cao , Shao-Jen Weng , Che-Hung Tsai

Automatic identification of brain lesions from magnetic resonance imaging (MRI) scans of stroke survivors would be a useful aid in patient diagnosis and treatment planning. We propose a multi-modal multi-path convolutional neural network…

Computer Vision and Pattern Recognition · Computer Science 2019-05-28 Yunzhe Xue , Fadi G. Farhat , Olga Boukrina , A . M. Barrett , Jeffrey R. Binder , Usman W. Roshan , William W. Graves

The integration of multi-modal Magnetic Resonance Imaging (MRI) and clinical data holds great promise for enhancing the diagnosis of neurological disorders (NDs) in real-world clinical settings. Deep Learning (DL) has recently emerged as a…

Image and Video Processing · Electrical Eng. & Systems 2025-06-19 Wajih Hassan Raza , Aamir Bader Shah , Yu Wen , Yidan Shen , Juan Diego Martinez Lemus , Mya Caryn Schiess , Timothy Michael Ellmore , Renjie Hu , Xin Fu

Stroke poses an immense public health burden and remains among the primary causes of death and disability worldwide. Emergent therapy is often precluded by late or indeterminate times of onset before initial clinical presentation. Rapid,…

Medical Physics · Physics 2021-04-16 Leeor Alon , Seena Dehkharghani

A key challenge in ischemic stroke diagnosis using medical imaging is the accurate localization of the occluded vessel. Current machine learning methods in focus primarily on lesion segmentation, with limited work on vessel localization. In…

Computer Vision and Pattern Recognition · Computer Science 2025-10-14 Mohamed Hamad , Muhammad Khan , Tamer Khattab , Mohamed Mabrok
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