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This paper introduces a new approach to automatically quantify the severity of knee OA using X-ray images. Automatically quantifying knee OA severity involves two steps: first, automatically localizing the knee joints; next, classifying the…
Interstitial lung disease (ILD) is a leading cause of morbidity and mortality in systemic sclerosis (SSc). Chest computed tomography (CT) is the primary imaging modality for diagnosing and monitoring lung complications in SSc patients.…
Minimizing invasive diagnostic procedures to reduce the risk of patient injury and infection is a central goal in medical imaging. And yet, noninvasive diagnosis of perineural invasion (PNI), a critical prognostic factor involving…
Pathologists are facing an increasing workload due to a growing volume of cases and the need for more comprehensive diagnoses. Aiming to facilitate workload reduction and faster turnaround times, we developed an artificial intelligence (AI)…
This chapter presents the investigations and the results of feature learning using convolutional neural networks to automatically assess knee osteoarthritis (OA) severity and the associated clinical and diagnostic features of knee OA from…
Gene expression can be used to subtype breast cancer with improved prediction of risk of recurrence and treatment responsiveness over that obtained using routine immunohistochemistry (IHC). However, in the clinic, molecular profiling is…
We propose an automated method based on deep learning to compute the cardiothoracic ratio and detect the presence of cardiomegaly from chest radiographs. We develop two separate models to demarcate the heart and chest regions in an X-ray…
Recent advances in automated radiology report generation from chest X-rays using deep learning algorithms have the potential to significantly reduce the arduous workload of radiologists. However, due to the inherent massive data bias in…
Recent advancements in computer vision promise to automate medical image analysis. Rheumatoid arthritis is an autoimmune disease that would profit from computer-based diagnosis, as there are no direct markers known, and doctors have to rely…
To reduce the amount of required labeled data for lung disease severity classification from chest X-rays (CXRs) under class imbalance, this study applied deep active learning with a Bayesian Neural Network (BNN) approximation and weighted…
Purpose: To determine whether deep learning-based algorithms applied to breast MR images can aid in the prediction of occult invasive disease following the di- agnosis of ductal carcinoma in situ (DCIS) by core needle biopsy. Material and…
Multiparametric magnetic resonance imaging (mp-MRI) has shown excellent results in the detection of prostate cancer (PCa). However, characterizing prostate lesions aggressiveness in mp-MRI sequences is impossible in clinical practice, and…
We present an operational component of a real-world patient triage system. Given a specific patient presentation, the system is able to assess the level of medical urgency and issue the most appropriate recommendation in terms of best point…
Background: Dental caries diagnosis requires the manual inspection of diagnostic bitewing images of the patient, followed by a visual inspection and probing of the identified dental pieces with potential lesions. Yet the use of artificial…
Epicardial adipose tissue (EAT) is known for its pro-inflammatory properties and association with Coronavirus Disease 2019 (COVID-19) severity. However, current EAT segmentation methods do not consider positional information. Additionally,…
Objectives: To overcome challenges in diagnosing pericoronitis on panoramic radiographs, an AI-assisted assessment system integrating anatomical localization, pathological classification, and interpretability. Methods: A two-stage deep…
Objectives To investigate the use of a Bayesian joint modelling approach to predict overall survival (OS) from immature clinical trial data using an intermediate biomarker. To compare the results with a typical parametric approach of…
Deep learning is quickly becoming the leading methodology for medical image analysis. Given a large medical archive, where each image is associated with a diagnosis, efficient pathology detectors or classifiers can be trained with virtually…
This paper addresses the medical imaging problem of joint detection in the upper limbs, viz. elbow, shoulder, wrist and finger joints. Localization of joints from X-Ray and Computerized Tomography (CT) scans is an essential step for the…
Background: Osteoporosis and osteopenia are often undiagnosed until fragility fractures occur. Dual-energy X-ray absorptiometry (DXA) is the reference standard for bone mineral density (BMD) assessment, but access remains limited. Knee…