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The distinct timescales of synaptic plasticity and neural activity dynamics play an important role in the brain's learning and memory systems. Activity-dependent plasticity reshapes neural circuit architecture, determining spontaneous and…

Neurons and Cognition · Quantitative Biology 2023-06-30 Heather L Cihak , Zachary P Kilpatrick

This work presents a data-driven reduced-order modeling framework to accelerate the computations of $N$-body dynamical systems and their pair-wise interactions. The proposed framework differs from traditional acceleration methods, like the…

Computational Engineering, Finance, and Science · Computer Science 2022-04-13 Steven N. Rodriguez , Athanasios P. Iliopoulos , Kevin T. Carlberg , Steven L. Brunton , John C. Steuben , John G. Michopoulos

Medical images used in clinical practice are heterogeneous and not the same quality as scans studied in academic research. Preprocessing breaks down in extreme cases when anatomy, artifacts, or imaging parameters are unusual or protocols…

Image and Video Processing · Electrical Eng. & Systems 2022-08-31 Mostafa Mehdipour Ghazi , Mads Nielsen

The brain is a nonlinear and highly Recurrent Neural Network (RNN). This RNN is surprisingly plastic and supports our astonishing ability to learn and execute complex tasks. However, learning is incredibly complicated due to the brain's…

Neural and Evolutionary Computing · Computer Science 2023-03-14 Mohammad Modiri

We demonstrate a new, hybrid symbolic-numerical method for the automatic synthesis of all families of translation operators required for the execution of the Fast Multipole Method (FMM). Our method is applicable in any dimensionality and to…

Numerical Analysis · Mathematics 2023-05-30 Isuru Fernando , Andreas Klöckner

Understanding brain disorders is crucial for accurate clinical diagnosis and treatment. Recent advances in Multimodal Large Language Models (MLLMs) offer a promising approach to interpreting medical images with the support of text…

Image and Video Processing · Electrical Eng. & Systems 2025-06-03 Jing Zhang , Xiaowei Yu , Yanjun Lyu , Lu Zhang , Tong Chen , Chao Cao , Yan Zhuang , Minheng Chen , Tianming Liu , Dajiang Zhu

The brain can learn to execute a wide variety of tasks quickly and efficiently. Nevertheless, most of the mechanisms that enable us to learn are unclear or incredibly complicated. Recently, considerable efforts have been made in…

Neural and Evolutionary Computing · Computer Science 2023-03-28 Mohammad Modiri

One of the important advantages of musculoskeletal humanoids is that the muscle arrangement can be easily changed and the number of muscles can be increased according to the situation. In this study, we describe an overall system of muscle…

Robotics · Computer Science 2024-11-12 Kento Kawaharazuka , Akihiro Miki , Yasunori Toshimitsu , Kei Okada , Masayuki Inaba

Understanding how the brain learns to compute functions reliably, efficiently and robustly with noisy spiking activity is a fundamental challenge in neuroscience. Most sensory and motor tasks can be described as dynamical systems and could…

Neurons and Cognition · Quantitative Biology 2017-05-24 Sophie Denève , Alireza Alemi , Ralph Bourdoukan

This is the first in a series of connected papers discussing the problem of a dynamically reconfigurable universal learning neurocomputer that could serve as a computational model for the whole human brain. The whole series is entitled "The…

Artificial Intelligence · Computer Science 2007-05-23 Victor Eliashberg

As numerical simulations grow in complexity, their demands on computing time and energy increase. Accelerators for numerical computation offer significant efficiency gains in many computationally-intensive scientific fields, but their use…

Simulating large-scale articulated assemblies poses a significant challenge due to the numerical stiffness and geometric complexity of jointed structures. Conventional rigid body solvers struggle with the high nonlinearity induced by…

This chapter sheds light on the synaptic organization of the brain from the perspective of computational neuroscience. It provides an introductory overview on how to account for empirical data in mathematical models, implement such models…

Many biological phenomena are inherently multiscale, i.e. they are characterized by interactions involving different spatial and temporal scales simultaneously. Though several approaches have been proposed to provide "multilayer" models,…

Computational Engineering, Finance, and Science · Computer Science 2010-11-03 Diletta Cacciagrano , Flavio Corradini , Emanuela Merelli , Luca Tesei

This paper introduces a new local plastic correction algorithm that is aimed at accelerating elasto-plastic finite element (FE) simulations for structural problems exhibiting localised plasticity (around e.g. notches, geometrical defects).…

Computational Engineering, Finance, and Science · Computer Science 2024-09-26 Abhishek Palchoudhary , Simone Peter , Vincent Maurel , Cristian Ovalle , Pierre Kerfriden

In this work, we have developed a multiscale computational algorithm to couple finite element method with an open source molecular dynamics code --- the Large scale Atomic/Molecular Massively Parallel Simulator (LAMMPS) --- to perform…

Soft Condensed Matter · Physics 2019-09-17 Takahiro Murashima , Shingo Urata , Shaofan Li

We present a novel platform for the large-scale simulation of fibrous structures immersed in a Stokesian fluid and evolving under confinement or in free-space. One of the main motivations for this work is to study the dynamics of fiber…

Numerical Analysis · Mathematics 2017-01-04 Ehssan Nazockdast , Abtin Rahimian , Denis Zorin , Michael Shelley

Differentiable simulators provide an avenue for closing the sim-to-real gap by enabling the use of efficient, gradient-based optimization algorithms to find the simulation parameters that best fit the observed sensor readings. Nonetheless,…

Robotics · Computer Science 2021-05-21 Eric Heiden , David Millard , Erwin Coumans , Yizhou Sheng , Gaurav S. Sukhatme

We present a new scheme to compensate for the small-scales approximations resulting from Particle-Mesh (PM) schemes for cosmological N-body simulations. This kind of simulations are fast and low computational cost realizations of the large…

Cosmology and Nongalactic Astrophysics · Physics 2022-07-21 Denise Lanzieri , François Lanusse , Jean-Luc Starck

We introduce Scaffold Prompt Tuning (ScaPT), a novel prompt-based framework for adapting large-scale functional magnetic resonance imaging (fMRI) pre-trained models to downstream tasks, with high parameter efficiency and improved…

Neurons and Cognition · Quantitative Biology 2024-08-21 Zijian Dong , Yilei Wu , Zijiao Chen , Yichi Zhang , Yueming Jin , Juan Helen Zhou
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