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A mechanism is proposed for increasing selectivity of olfactory bulb projection neurons as compared to the olfactory receptor neurons, which could operate under low odor concentration, when the lateral inhibition mechanism becomes…

Neurons and Cognition · Quantitative Biology 2021-11-09 Alexander Vidybida

Biological cells are able to accurately sense chemicals with receptors at their surfaces, allowing cells to move towards sources of attractant and away from sources of repellent. The accuracy of sensing chemical concentration is ultimately…

Subcellular Processes · Quantitative Biology 2015-05-14 Robert G. Endres , Ned S. Wingreen

Olfaction sensing in autonomous robotics faces challenges in dynamic operations, energy efficiency, and edge processing. It necessitates a machine learning algorithm capable of managing real-world odor interference, ensuring resource…

Signal Processing · Electrical Eng. & Systems 2024-07-09 Rizwana Kausar , Fakhreddine Zayer , Jaime Viegas , Jorge Dias

Environmental factors determine the smells we perceive, but societal factors factors shape the importance, sentiment and biases we give to them. Descriptions of smells in text, or as we call them `smell experiences', offer a window into…

Computation and Language · Computer Science 2020-12-08 Ryan Brate , Paul Groth , Marieke van Erp

Most sensory cells use surface receptors to detect environmental stimuli and initiate downstream signaling. Cooperative interactions among sensory receptors is known to play a crucial role in enhancing the sensitivity of biochemical…

Molecular Networks · Quantitative Biology 2014-01-15 Jianmin Sun , Michael Grabe

Odor-based Molecular Communication (OMC) employs odor molecules to convey information, contributing to the realization of the Internet of Everything (IoE) vision. Despite this, the practical deployment of OMC systems is currently limited by…

Signal Processing · Electrical Eng. & Systems 2026-02-03 Ahmet B. Kilic , Fatih E. Bilgen , Ozgur B. Akan

Local computation in microcircuits is an essential feature of distributed information processing in vertebrate and invertebrate brains. The insect antennal lobe represents a spatially confined local network that processes high-dimensional…

Neurons and Cognition · Quantitative Biology 2012-12-27 Anneke Meyer , Giovanni Galizia , Martin P. Nawrot

Selectivity of olfactory receptor neuron (ORN) is compared with that of its receptor proteins (R) with fluctuations of odor binding-releasing process taken into account. The binding-releasing process is modeled as N Bernoulli trials, where…

Biological Physics · Physics 2022-07-20 A. Vidybida

Deep learning methods have been widely applied to visual and acoustic technology. In this paper, we proposed an odor labeling convolutional encoder-decoder (OLCE) for odor identification in machine olfaction. OLCE composes a convolutional…

Machine Learning · Computer Science 2021-01-07 Tengteng Wen , Zhuofeng Mo , Jingshan Li , Qi Liu , Liming Wu , Dehan Luo

The mammalian olfactory system learns rapidly from very few examples, presented in unpredictable online sequences, and then recognizes these learned odors under conditions of substantial interference without exhibiting catastrophic…

Neural and Evolutionary Computing · Computer Science 2019-07-15 Ayon Borthakur , Thomas A. Cleland

We address the problem of inferring the location of a target that releases odor in the presence of turbulence. Input for the inference is provided by many sensors scattered within the odor plume. Drawing inspiration from distributed…

Biological Physics · Physics 2026-01-13 Francesco Marcolli , Martin James , Agnese Seminara

Biological circuits have evolved to incorporate multiple modules that perform similar functions. In the fly olfactory circuit, both lateral inhibition (LI) and neuronal spike frequency adaptation (SFA) are thought to enhance pattern…

Neural and Evolutionary Computing · Computer Science 2025-10-27 Haiyang Li , Liao Yu , Qiang Yu , Yunliang Zang

One of the key challenges to predict odor from molecular structure is unarguably our limited understanding of the odor space and the complexity of the underlying structure-odor relationships. Here, we show that the predictive performance of…

Quantitative Methods · Quantitative Biology 2025-08-14 Akshay Sajan , Stijn Sluis , Reza Haydarlou , Sanne Abeln , Pasquale Lisena , Raphael Troncy , Caro Verbeek , Inger Leemans , Halima Mouhib

Natural odor environments present turbulent and dynamic conditions, causing chemical signals to fluctuate in space, time, and intensity. While many species have evolved highly adaptive behavioral responses to such variability, the emerging…

Neural and Evolutionary Computing · Computer Science 2024-12-31 Shavika Rastogi , Nik Dennler , Michael Schmuker , André van Schaik

The insect olfactory system, which includes the antennal lobe (AL), mushroom body (MB), and ancillary structures, is a relatively simple neural system capable of learning. Its structural features, which are widespread in biological neural…

Neurons and Cognition · Quantitative Biology 2018-02-09 Charles B. Delahunt , Jeffrey A. Riffell , J. Nathan Kutz

This work presents a general chemical reaction network theory for olfactory sensing processes that employ G-protein-coupled receptors as olfactory receptors (ORs). The theory is applicable to general mixtures of odorants and an arbitrary…

Molecular Networks · Quantitative Biology 2023-09-06 Won Kyu Kim , Kiri Choi , Changbong Hyeon , Seogjoo J. Jang

Storing memory for molecular recognition is an efficient strategy for responding to external stimuli. Biological processes use different strategies to store memory. In the olfactory cortex, synaptic connections form when stimulated by an…

Biological Physics · Physics 2021-06-07 Oskar H Schnaack , Luca Peliti , Armita Nourmohammad

Molecular communication is a new, active area of research that has created a paradigm shift in the way a communication system is perceived. An artificial molecular communication network is created using biological molecules for encoding,…

Emerging Technologies · Computer Science 2023-12-01 Aditya Powari , Ozgur B. Akan

This article provides a background and descriptive analysis of insect memory and the coding of olfactory sensation in Drosophila, presenting graphs and summary statistics from a large dataset of neurons and synapses that was recently made…

Neurons and Cognition · Quantitative Biology 2022-09-07 Chris Rohlfs

Inelastic electron transfer being regarded as one of the potential mechanisms to explain the odorant recognition in the atomic-scale processes is still a matter of intense debate. Here, we propose multiphonon processes of electrons transfer…

Biological Physics · Physics 2021-08-02 Shu-Quan Zhang , Yu Cui , Xue-Wei Li , Yong Sun , Zi-Wu Wang