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While robotic perception has advanced rapidly in vision and touch, enabling robots to reason about indoor fungal contamination from weak, diffusion-dominated chemical signals remains an open challenge. We introduce Scensory, a…

Signal Processing · Electrical Eng. & Systems 2026-05-29 Yanbaihui Liu , Erica Babusci , Claudia K. Gunsch , Boyuan Chen

Cells in natural environments like tissue or soil sense and respond to extracellular ligands with intricately structured and non-monotonic spatial distributions that are sculpted by processes such as fluid flow and substrate adhesion.…

Cell Behavior · Quantitative Biology 2021-07-05 Zitong Jerry Wang , Matt Thomson

Animals use stereo sampling of odor concentration to localize sources and follow odor trails. We analyze the dynamics of a bilateral model that depends on the simultaneous comparison between odor concentrations detected by left and right…

Quantitative Methods · Quantitative Biology 2021-03-16 Nour Riman , Jonathan D. Victor , Sebastian D. Boie , Bard Ermentrout

In the olfactory system, odor percepts retain their identity despite substantial variations in concentration, timing, and background. We propose a novel strategy for encoding intensity-invariant stimuli identity that is based on…

Neurons and Cognition · Quantitative Biology 2016-09-09 Daniel Kepple , Hamza Giaffar , Dmitry Rinberg , Alexei Koulakov

The vibrational theory of olfaction was posited to explain subtle effects in the sense of smell inexplicable by models in which molecular structure alone determines an odorant's smell. Amazingly, behavioral and neurophysiological evidence…

Biological Physics · Physics 2019-05-01 Nishattasnim Liza , Enrique P. Blair

We present a novel machine learning architecture for classification suggested by experiments on olfactory systems. The network separates input stimuli, represented as spatially distinct currents, via winnerless competition---a process based…

Biological Physics · Physics 2020-06-18 Jason A. Platt , Anna Miller , Lawson Fuller , Henry D. I. Abarbanel

Increasing attention has been recently devoted to protein-based nanobiosensors. The main reason is the huge number of possible technological applications, going from drug detection to cancer early diagnosis. Their operating model is based…

Mesoscale and Nanoscale Physics · Physics 2011-07-15 Eleonora Alfinito , Jean-Francois Millithaler , Lino Reggiani , Nadia Zine , Nicole Jaffrezic-Renault

Molecular communication (MC) has promising potential and a wide range of applications. However, odor-based communication which is common in nature, has not been sufficiently examined within the context of MC, yet. In this paper, we…

Emerging Technologies · Computer Science 2024-11-01 Fatih E. Bilgen , Ahmet B. Kilic , Ozgur B. Akan

It was observed before that due to convergence in the olfactory system a possible amplification can be as large as the degree of convergence. This is in the case when a single impulse from the converging inputs is enough to trigger the…

Neurons and Cognition · Quantitative Biology 2019-01-28 Alexander Vidybida

Plants and insects communicate using chemical signals like volatile organic compounds (VOCs). A plant encodes information using different blends of VOCs, which propagate through the air to represent different symbolic information. This…

Information Theory · Computer Science 2026-02-10 Bitop Maitra , Murat Kuscu , Ozgur B. Akan

Predicting the relationship between a molecule's structure and its odor remains a difficult, decades-old task. This problem, termed quantitative structure-odor relationship (QSOR) modeling, is an important challenge in chemistry, impacting…

This study investigates the dynamics of non-spatial specializations in hippocampal place cells during exposure to novel environments. Hippocampal place cells, known for their role in spatial mapping, exhibit multi-modal responses to sensory…

Olfactory perception plays a critical role in both human and organismal interactions, yet understanding of its underlying mechanisms and influencing factors remain insufficient. Molecular structures influence odor perception through…

Machine Learning · Computer Science 2025-02-04 HongXin Xie , JianDe Sun , Yi Shao , Shuai Li , Sujuan Hou , YuLong Sun , Jian Wang

Before aerosols can be sensed, sampling technologies must capture the particulate matter of interest. To that end, for systems deployed in open environments where the location of the aerosol is unknown, extending the reach of the sampler…

Systems and Control · Electrical Eng. & Systems 2025-05-26 Yahya Naveed , Julia Gersey , Pei Zhang

Navigation by scent is a capability in robotic systems that is rising in demand. However, current methods often suffer from ambiguities, particularly when robots misattribute odours to incorrect objects due to limitations in olfactory…

Robotics · Computer Science 2025-09-23 Kordel K. France , Ovidiu Daescu

We introduce and study an artificial neural network, inspired by the probabilistic Receptor Affinity Distribution model of olfaction. Our system consists on N sensory neurons whose outputs converge on a single processing linear threshold…

Disordered Systems and Neural Networks · Physics 2007-05-23 N. Caticha , J. E. Palo Tejada , D. Lancet , E. Domany

Olfaction lies at the intersection of chemical structure, neural encoding, and linguistic perception, yet existing representation methods fail to fully capture this pathway. Current approaches typically model only isolated segments of the…

Computation and Language · Computer Science 2026-04-21 Yanyi Su , Hongshuai Wang , Zhifeng Gao , Jun Cheng

People are able to detect up to 1 trillion odors. Yet, city planning is concerned only with a few bad odors, mainly because odors are currently captured only through complaints made by urban dwellers. To capture both good and bad odors, we…

Social and Information Networks · Computer Science 2016-05-24 Daniele Quercia , Luca Maria Aiello , Rossano Schifanella

We explore a suite of generative modelling techniques to efficiently navigate and explore the complex landscapes of odor and the broader chemical space. Unlike traditional approaches, we not only generate molecules but also predict the odor…

Machine Learning · Computer Science 2025-02-03 Mrityunjay Sharma , Sarabeshwar Balaji , Pinaki Saha , Ritesh Kumar

The mammalian brain is a metabolically expensive device, and evolutionary pressures have presumably driven it to make productive use of its resources. For sensory areas, this concept has been expressed more formally as an optimality…

Neurons and Cognition · Quantitative Biology 2016-03-02 Deep Ganguli , Eero P. Simoncelli