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The outbreak of COVID-19 exposed the inadequacy of our technical tools for home health surveillance, and recent studies have shown the potential of smartphones as a universal optical microscopic imaging platform for such applications.…

Image and Video Processing · Electrical Eng. & Systems 2023-12-20 Haoran Zhang , Weiyi Zhang , Zirui Zuo , Jianlong Yang

Nowadays is very common to find headlines in the media where it is stated that 3D printing is a technology called to change our lives in the near future. For many authors, we are living in times of a third industrial revolution. Howerver,…

Instrumentation and Detectors · Physics 2017-02-08 L. J. Salazar-Serrano , A. Valencia , J. P. Torres

Poor access to eye care is a major global challenge that could be ameliorated by low-cost, portable, and easy-to-use diagnostic technologies. Diffuser-based imaging has the potential to enable inexpensive, compact optical systems that can…

Medical Physics · Physics 2020-06-23 Yunzhe Li , Gregory N. McKay , Nicholas J. Durr , Lei Tian

3D printing technologies are currently enabling the fabrication of objects with complex architectures and tailored properties. In such framework, the production of 3D optical structures, which are typically based on optical transparent…

Applied Physics · Physics 2018-07-11 L. Persano , F. Cardarelli , A. Arinstein , S. Uttiya , E. Zussman , D. Pisignano , A. Camposeo

In this work, we describe the development and application of a low-cost fluid interface visualizer referred to as the ``Meniscope.'' The device works using a color-based surface gradient detector method that maps the gradient of an…

Optics · Physics 2026-03-19 Daniel M. Harris

We describe a project-based physics lab, which we proposed to third-year university students. Theses labs are based on new open-source low-cost equipment (Arduino microcontrollers and compatible sensors). Students are given complete…

Physics Education · Physics 2017-03-08 F. Bouquet , J. Bobroff , M. Fuchs-Gallezot , L. Maurines

Fast confocal imaging was achieved by combining remote focusing with differential spinning disk optical sectioning to rapidly acquire images of live samples at cellular resolution. Axial and lateral full width half maxima less than 5 um and…

We consider the numerical optimization of performance for a computational extension of a confocal microscope. Using a system where the pinhole detector is replaced with a detector array, we seek to exploit this additional information for…

Signal Processing · Electrical Eng. & Systems 2020-12-15 Keith Dillon

Prototype optical microscopes, built to pursue developments in advanced imaging techniques, need specific optomechanical constructions: preferably with high flexibility in the elements arrangement, easy access to the optical paths,…

Instrumentation and Detectors · Physics 2023-05-30 Łukasz Zinkiewicz , Milena Królikowska , Alexander Krupiński-Ptaszek , Piotr Wasylczyk

This paper presents the mechanical design of a distal scanner to perform a spiral scan for mosaic-imaging with a confocal microlaparoscope. First, it is demonstrated with ex vivo experiments that a spiral scan performs better than a raster…

Robotics · Computer Science 2018-04-16 Mustafa Suphi Erden , Benoît Rosa , Jérome Szewczyk , Guillaume Morel

Granular materials are complex multi-particle ensembles in which macroscopic properties are largely determined by inter-particle interactions between their numerous constituents. In order to understand and to predict their macroscopic…

Computerized tomography (CT) has been used for decades by medical professionals to detect and diagnose injuries and ailments. CT scanners are based on interesting physics, but due to their bulk, cost, and safety, hands on experience with a…

Physics Education · Physics 2021-01-28 Vincent Daley , Owen Paetkau , Mark Paetkau

We discuss the design of an inexpensive, high-throughput CCD spectrograph for a small telescope. By using optical fibers to carry the light from the telescope focus to a table-top spectrograph, one can minimize the weight carried by the…

Astrophysics · Physics 2008-11-26 Sheila J. Kannappan , Daniel G. Fabricant , Charles B. Hughes

Microfluidics have emerged as a vital tool in various scientific and engineering applications, ranging from biomedical diagnostics to chemical analysis. However, conventional fabrication methods often necessitate costly equipment and…

Instrumentation and Detectors · Physics 2023-08-07 Habilou Ouro-Koura , Ayobami Ogunmolasuyi , Othman Suleiman , Kausik S Das

Fast, volumetric imaging that integrates multiple imaging modalities is essential for probing dynamic, heterogeneous soft and biological matter. Here, we present the M3Scope, a simple yet versatile multiplane microscope that extends…

Miniature fluorescence microscopes are a standard tool in systems biology. However, widefield miniature microscopes capture only 2D information, and modifications that enable 3D capabilities increase the size and weight and have poor…

Image and Video Processing · Electrical Eng. & Systems 2020-10-13 Kyrollos Yanny , Nick Antipa , William Liberti , Sam Dehaeck , Kristina Monakhova , Fanglin Linda Liu , Konlin Shen , Ren Ng , Laura Waller

Many optical microscopy techniques rely on structured illumination by way of a projected image (eg. structured illumination microscopy) or a tailored angular distribution of light (eg. ptychography). Electro-optical equipment such as…

Physics Education · Physics 2020-09-23 Antony Orth

Learning miniaturization science remains challenging due to the non-intuitive behavior of microscale objects and complex assembly approaches. Traditional approaches for creating microsystems require expensive equipment, facilities, and…

Endoluminal surgery offers a minimally invasive option for early-stage gastrointestinal and urinary tract cancers but is limited by surgical tools and a steep learning curve. Robotic systems, particularly continuum robots, provide flexible…

As an important optical component, lens is widely used in scientific inquiry and production. At present, lens manufacturing mainly relies on grinding, polishing and other methods. However, these methods often require expensive equipment and…

Optics · Physics 2024-06-10 Chuanzhu Cheng , Fanru Kong , Yuqing Liu