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Objective: To construct an analytical model instead of local effect modeling for the prediction of the biological effectiveness of nanoparticle radiosensitization. Approach: An extended local effects model is first proposed with a more…

Fluorescence microscopy, widely used in the study of living cells, tissues, and organisms, often faces the challenge of photodamage. This is primarily caused by the interaction between light and biochemical components during the imaging…

Quantitative Methods · Quantitative Biology 2024-04-01 Estibaliz Gómez-de-Mariscal , Mario Del Rosario , Joanna W Pylvänäinen , Guillaume Jacquemet , Ricardo Henriques

In recent years, several successful applications of the Artificial Neural Networks (ANNs) have emerged in nuclear physics and high-energy physics, as well as in biology, chemistry, meteorology, and other fields of science. A major goal of…

In this work, an ontology-based model for AI-assisted medicine side-effect (SE) prediction is developed, where three main components, including the drug model, the treatment model, and the AI-assisted prediction model, of proposed model are…

Artificial Intelligence · Computer Science 2019-10-02 Yuanzhe Yao , Zeheng Wang , Liang Li , Kun Lu , Runyu Liu , Zhiyuan Liu , Jing Yan

Predicting patient features from single-cell data can help identify cellular states implicated in health and disease. Linear models and average cell type expressions are typically favored for this task for their efficiency and robustness,…

Machine Learning · Computer Science 2024-03-11 Jan P. Engelmann , Alessandro Palma , Jakub M. Tomczak , Fabian J. Theis , Francesco Paolo Casale

Neuropathies are gaining higher relevance in clinical settings, as they risk permanently jeopardizing a person's life. To support the recovery of patients, the use of fully implanted devices is emerging as one of the most promising…

Artificial Intelligence · Computer Science 2024-04-03 Antonio Coviello , Francesco Linsalata , Umberto Spagnolini , Maurizio Magarini

The application of artificial intelligence (AI) in medical imaging has revolutionized diagnostic practices, enabling advanced analysis and interpretation of radiological data. This study presents a comprehensive evaluation of…

Image and Video Processing · Electrical Eng. & Systems 2025-07-22 Zhijin He , Alan B. McMillan

Skin cancer is a serious worldwide health issue, precise and early detection is essential for better patient outcomes and effective treatment. In this research, we use modern deep learning methods and explainable artificial intelligence…

Image and Video Processing · Electrical Eng. & Systems 2023-12-19 Faysal Mahmud , Md. Mahin Mahfiz , Md. Zobayer Ibna Kabir , Yusha Abdullah

Advances in machine learning have created new opportunities to develop artificial intelligence (AI)-based clinical decision support systems using past clinical data and improve diagnosis decisions in life-threatening illnesses such breast…

Human-Computer Interaction · Computer Science 2024-12-17 Olya Rezaeian , Onur Asan , Alparslan Emrah Bayrak

The interactions between tumor cells and the tumor microenvironment (TME) dictate therapeutic efficacy of radiation and many systemic therapies in breast cancer. However, to date, there is not a widely available method to reproducibly…

CRISPR-based genome editing has revolutionized biotechnology, yet optimizing guide RNA (gRNA) design for efficiency and safety remains a critical challenge. Recent advances (2020--2025, updated to reflect current year if needed) demonstrate…

Quantitative Methods · Quantitative Biology 2025-08-29 Alireza Abbaszadeh , Armita Shahlai

Supervised machine learning classifiers sometimes face challenges related to the performance, accuracy, or overfitting. This paper introduces the Artificial Liver Classifier (ALC), a novel supervised learning model inspired by the human…

Artificial Intelligence · Computer Science 2025-09-24 Mahmood A. Jumaah , Yossra H. Ali , Tarik A. Rashid

While the Bayesian Information Criterion (BIC) and Akaike Information Criterion (AIC) are powerful tools for model selection in linear regression, they are built on different prior assumptions and thereby apply to different data generation…

Methodology · Statistics 2017-12-15 MB de Kock , HC Eggers

Accurate forecasting of contagious diseases is critical for public health policymaking and pandemic preparedness. We propose a new infectious disease forecasting model based on physics-informed neural networks (PINNs), an emerging…

Machine Learning · Computer Science 2025-04-30 Ying Qian , Kui Zhang , Éric Marty , Avranil Basu , Eamon B. O'Dea , Xianqiao Wang , Spencer Fox , Pejman Rohani , John M. Drake , He Li

Acid mine drainage (AMD) is one of the common environmental problems in the coal mining industry that was formed by the oxidation of sulfide minerals in the overburden or waste rock. The prediction of acid generation through AMD is…

Machine Learning · Computer Science 2024-09-05 Muhammad Sonny Abfertiawan , Muchammad Daniyal Kautsar , Faiz Hasan , Yoseph Palinggi , Kris Pranoto

Cancer is one of the leading causes of death worldwide. Fast and safe early-stage, pre- and intra-operative diagnostics can significantly contribute to successful cancer identification and treatment. Artificial intelligence has played an…

Tissues and Organs · Quantitative Biology 2022-08-10 Marina Zajnulina

In artificial intelligence (AI), the complexity of many models and processes surpasses human understanding, making it challenging to determine why a specific prediction is made. This lack of transparency is particularly problematic in…

Machine Learning · Statistics 2025-06-30 Alexandra Stadler , Werner G. Müller , Radoslav Harman

Breast cancer (BC) stands as one of the most common malignancies affecting women worldwide, necessitating advancements in diagnostic methodologies for better clinical outcomes. This article provides a comprehensive exploration of the…

Artificial Intelligence · Computer Science 2025-12-11 Samita Bai , Sidra Nasir , Rizwan Ahmed Khan , Alexandre Meyer , Hubert Konik

Artificial intelligence (AI)-driven decision support systems can improve diagnostic accuracy and efficiency in computational pathology. However, collaboration between human experts and AI may introduce cognitive biases such as automation…

Human-Computer Interaction · Computer Science 2026-03-16 Emely Rosbach , Jonas Ammeling , Jonathan Ganz , Christof Albert Bertram , Thomas Conrad , Andreas Riener , Marc Aubreville

With recent advancements in the development of artificial intelligence applications using theories and algorithms in machine learning, many accurate models can be created to train and predict on given datasets. With the realization of the…

Machine Learning · Computer Science 2024-03-29 Pei Xi , Lin