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This article describes the design, implementation, and results of the latest installment of the dermoscopic image analysis benchmark challenge. The goal is to support research and development of algorithms for automated diagnosis of…

Accurate assessment of lymph node size in 3D CT scans is crucial for cancer staging, therapeutic management, and monitoring treatment response. Existing state-of-the-art segmentation frameworks in medical imaging often rely on fully…

Purpose: Automatic methods are required for the early detection of hepatic steatosis to avoid progression to cirrhosis and cancer. Here, we developed a fully automated deep learning pipeline to quantify hepatic steatosis on non-contrast…

Quantitative Methods · Quantitative Biology 2022-02-08 Zhongyi Zhang , Jakob Weiss , Jana Taron , Roman Zeleznik , Michael T. Lu , Hugo J. W. L. Aerts

Evaluating expression of the Human epidermal growth factor receptor 2 (Her2) by visual examination of immunohistochemistry (IHC) on invasive breast cancer (BCa) is a key part of the diagnostic assessment of BCa due to its recognised…

In this study, we built an end-to-end tumor-infiltrating lymphocytes (TILs) assessment pipeline within QuPath, demonstrating the potential of easily accessible tools to perform complex tasks in a fully automatic fashion. First, we trained a…

Pathologists find tedious to examine the status of the sentinel lymph node on a large number of pathological scans. The examination process of such lymph node which encompasses metastasized cancer cells is histopathologically organized.…

Computer Vision and Pattern Recognition · Computer Science 2019-06-25 Amit Kumar Jaiswal , Ivan Panshin , Dimitrij Shulkin , Nagender Aneja , Samuel Abramov

This work summarizes the results of the largest skin image analysis challenge in the world, hosted by the International Skin Imaging Collaboration (ISIC), a global partnership that has organized the world's largest public repository of…

Lymph node metastasis is one of the most significant diagnostic indicators in breast cancer, which is traditionally observed under the microscope by pathologists. In recent years, computerized histology diagnosis has become one of the most…

Computer Vision and Pattern Recognition · Computer Science 2017-08-01 Huangjing Lin , Hao Chen , Qi Dou , Liansheng Wang , Jing Qin , Pheng-Ann Heng

In this work, we report the set-up and results of the Liver Tumor Segmentation Benchmark (LiTS), which was organized in conjunction with the IEEE International Symposium on Biomedical Imaging (ISBI) 2017 and the International Conferences on…

Computer Vision and Pattern Recognition · Computer Science 2022-11-28 Patrick Bilic , Patrick Christ , Hongwei Bran Li , Eugene Vorontsov , Avi Ben-Cohen , Georgios Kaissis , Adi Szeskin , Colin Jacobs , Gabriel Efrain Humpire Mamani , Gabriel Chartrand , Fabian Lohöfer , Julian Walter Holch , Wieland Sommer , Felix Hofmann , Alexandre Hostettler , Naama Lev-Cohain , Michal Drozdzal , Michal Marianne Amitai , Refael Vivantik , Jacob Sosna , Ivan Ezhov , Anjany Sekuboyina , Fernando Navarro , Florian Kofler , Johannes C. Paetzold , Suprosanna Shit , Xiaobin Hu , Jana Lipková , Markus Rempfler , Marie Piraud , Jan Kirschke , Benedikt Wiestler , Zhiheng Zhang , Christian Hülsemeyer , Marcel Beetz , Florian Ettlinger , Michela Antonelli , Woong Bae , Míriam Bellver , Lei Bi , Hao Chen , Grzegorz Chlebus , Erik B. Dam , Qi Dou , Chi-Wing Fu , Bogdan Georgescu , Xavier Giró-i-Nieto , Felix Gruen , Xu Han , Pheng-Ann Heng , Jürgen Hesser , Jan Hendrik Moltz , Christian Igel , Fabian Isensee , Paul Jäger , Fucang Jia , Krishna Chaitanya Kaluva , Mahendra Khened , Ildoo Kim , Jae-Hun Kim , Sungwoong Kim , Simon Kohl , Tomasz Konopczynski , Avinash Kori , Ganapathy Krishnamurthi , Fan Li , Hongchao Li , Junbo Li , Xiaomeng Li , John Lowengrub , Jun Ma , Klaus Maier-Hein , Kevis-Kokitsi Maninis , Hans Meine , Dorit Merhof , Akshay Pai , Mathias Perslev , Jens Petersen , Jordi Pont-Tuset , Jin Qi , Xiaojuan Qi , Oliver Rippel , Karsten Roth , Ignacio Sarasua , Andrea Schenk , Zengming Shen , Jordi Torres , Christian Wachinger , Chunliang Wang , Leon Weninger , Jianrong Wu , Daguang Xu , Xiaoping Yang , Simon Chun-Ho Yu , Yading Yuan , Miao Yu , Liping Zhang , Jorge Cardoso , Spyridon Bakas , Rickmer Braren , Volker Heinemann , Christopher Pal , An Tang , Samuel Kadoury , Luc Soler , Bram van Ginneken , Hayit Greenspan , Leo Joskowicz , Bjoern Menze

Breast cancer is the most common malignancy in women, being responsible for more than half a million deaths every year. As such, early and accurate diagnosis is of paramount importance. Human expertise is required to diagnose and correctly…

The analysis of FFPE tissue sections stained with haematoxylin and eosin (H&E) or immunohistochemistry (IHC) is an essential part of the pathologic assessment of surgically resected breast cancer specimens. IHC staining has been broadly…

In this article, we describe the design and implementation of a publicly accessible dermatology image analysis benchmark challenge. The goal of the challenge is to sup- port research and development of algorithms for automated diagnosis of…

Computer Vision and Pattern Recognition · Computer Science 2016-05-05 David Gutman , Noel C. F. Codella , Emre Celebi , Brian Helba , Michael Marchetti , Nabin Mishra , Allan Halpern

Liver cancer, especially hepatocellular carcinoma (HCC), imposes a substantial global disease burden. Accurate diagnosis and prognostic assessment directly influence treatment selection and patient survival, and pathological examination…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Ying Xiao , Shimiao Tang , Xitong Ling , Weiming Chen , Jun Wang , Jiawen Li , Huaitian Yuan , Jianghui Yang , Bowen Li , Huan Li , Yiting Meng , Tian Guan , Yonghong He , Hongfang Yin

Immunohistochemistry (IHC) provides information on protein expression in tissue sections and is commonly used to support pathology diagnosis and disease triage. While AI models for H\&E-stained slides show promise, their applicability to…

In numerous studies, deep learning algorithms have proven their potential for the analysis of histopathology images, for example, for revealing the subtypes of tumors or the primary origin of metastases. These models require large datasets…

Computer Vision and Pattern Recognition · Computer Science 2024-11-05 Jonathan Ganz , Jonas Ammeling , Samir Jabari , Katharina Breininger , Marc Aubreville

The current study of cell architecture of inflammation in histopathology images commonly performed for diagnosis and research purposes excludes a lot of information available on the biopsy slide. In autoimmune diseases, major outstanding…

Image and Video Processing · Electrical Eng. & Systems 2022-10-25 Pranav Singh , Jacopo Cirrone

Increased levels of tumor infiltrating lymphocytes (TILs) in cancer tissue indicate favourable outcomes in many types of cancer. Manual quantification of immune cells is inaccurate and time consuming for pathologists. Our aim is to leverage…

The field of histology relies heavily on antiquated tissue processing and staining techniques that limit the efficiency of pathologic diagnoses of cancer and other diseases. Current staining and advanced labeling methods are often…

Purpose - To characterise and assess the quality of published research evaluating artificial intelligence (AI) methods for ovarian cancer diagnosis or prognosis using histopathology data. Methods - A search of PubMed, Scopus, Web of…

Image and Video Processing · Electrical Eng. & Systems 2023-06-19 Jack Breen , Katie Allen , Kieran Zucker , Pratik Adusumilli , Andy Scarsbrook , Geoff Hall , Nicolas M. Orsi , Nishant Ravikumar

Purpose: In this work, we present a collaboration to create a validation dataset of pathologist annotations for algorithms that process whole slide images (WSIs). We focus on data collection and evaluation of algorithm performance in the…