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Melanoma diagnosed and treated in its early stages can increase the survival rate. A projected increase in skin cancer incidents and a dearth of dermatopathologists have emphasized the need for computational pathology (CPATH) systems. CPATH…

Image and Video Processing · Electrical Eng. & Systems 2023-11-07 Neel Kanwal , Roger Amundsen , Helga Hardardottir , Luca Tomasetti , Erling Sandoy Undersrud , Emiel A. M. Janssen , Kjersti Engan

Label-free approaches are attractive in cytological imaging due to their flexibility and cost efficiency. They are supported by machine learning methods, which, despite the lack of labeling and the associated lower contrast, can classify…

Computer Vision and Pattern Recognition · Computer Science 2023-11-27 Stefan Röhrl , Johannes Groll , Manuel Lengl , Simon Schumann , Christian Klenk , Dominik Heim , Martin Knopp , Oliver Hayden , Klaus Diepold

Automated semantic segmentation of whole-slide images (WSIs) stained with hematoxylin and eosin (H&E) is essential for large-scale artificial intelligence-based biomarker analysis in breast cancer. However, existing public datasets for…

Human-in-the-loop optimization (HILO) is a promising approach for personalizing visual prostheses by iteratively refining stimulus parameters based on user feedback. Previous work demonstrated HILO's efficacy in simulation, but its…

Machine Learning · Computer Science 2025-04-29 Eirini Schoinas , Adyah Rastogi , Anissa Carter , Jacob Granley , Michael Beyeler

Clinical cystoscopy, the current standard for bladder cancer diagnosis, suffers from significant reliance on physician expertise, leading to variability and subjectivity in diagnostic outcomes. There is an urgent need for objective,…

Image and Video Processing · Electrical Eng. & Systems 2025-08-22 Jinliang Yu , Mingduo Xie , Yue Wang , Tianfan Fu , Xianglai Xu , Jiajun Wang

Large language models (LLMs) have significantly advanced natural language processing tasks, yet they are susceptible to generating inaccurate or unreliable responses, a phenomenon known as hallucination. In critical domains such as health…

Computation and Language · Computer Science 2024-09-20 Sumera Anjum , Hanzhi Zhang , Wenjun Zhou , Eun Jin Paek , Xiaopeng Zhao , Yunhe Feng

We introduce a new AI-ready computational pathology dataset containing restained and co-registered digitized images from eight head-and-neck squamous cell carcinoma patients. Specifically, the same tumor sections were stained with the…

Image and Video Processing · Electrical Eng. & Systems 2023-05-29 Parmida Ghahremani , Joseph Marino , Juan Hernandez-Prera , Janis V. de la Iglesia , Robbert JC Slebos , Christine H. Chung , Saad Nadeem

Histopathology can help clinicians make accurate diagnoses, determine disease prognosis, and plan appropriate treatment strategies. As deep learning techniques prove successful in the medical domain, the primary challenges become limited…

Computer Vision and Pattern Recognition · Computer Science 2024-07-11 Zhe Li , Bernhard Kainz

International benchmarking competitions have become fundamental for the comparative performance assessment of image analysis methods. However, little attention has been given to investigating what can be learnt from these competitions. Do…

Computer Vision and Pattern Recognition · Computer Science 2023-04-03 Matthias Eisenmann , Annika Reinke , Vivienn Weru , Minu Dietlinde Tizabi , Fabian Isensee , Tim J. Adler , Sharib Ali , Vincent Andrearczyk , Marc Aubreville , Ujjwal Baid , Spyridon Bakas , Niranjan Balu , Sophia Bano , Jorge Bernal , Sebastian Bodenstedt , Alessandro Casella , Veronika Cheplygina , Marie Daum , Marleen de Bruijne , Adrien Depeursinge , Reuben Dorent , Jan Egger , David G. Ellis , Sandy Engelhardt , Melanie Ganz , Noha Ghatwary , Gabriel Girard , Patrick Godau , Anubha Gupta , Lasse Hansen , Kanako Harada , Mattias Heinrich , Nicholas Heller , Alessa Hering , Arnaud Huaulmé , Pierre Jannin , Ali Emre Kavur , Oldřich Kodym , Michal Kozubek , Jianning Li , Hongwei Li , Jun Ma , Carlos Martín-Isla , Bjoern Menze , Alison Noble , Valentin Oreiller , Nicolas Padoy , Sarthak Pati , Kelly Payette , Tim Rädsch , Jonathan Rafael-Patiño , Vivek Singh Bawa , Stefanie Speidel , Carole H. Sudre , Kimberlin van Wijnen , Martin Wagner , Donglai Wei , Amine Yamlahi , Moi Hoon Yap , Chun Yuan , Maximilian Zenk , Aneeq Zia , David Zimmerer , Dogu Baran Aydogan , Binod Bhattarai , Louise Bloch , Raphael Brüngel , Jihoon Cho , Chanyeol Choi , Qi Dou , Ivan Ezhov , Christoph M. Friedrich , Clifton Fuller , Rebati Raman Gaire , Adrian Galdran , Álvaro García Faura , Maria Grammatikopoulou , SeulGi Hong , Mostafa Jahanifar , Ikbeom Jang , Abdolrahim Kadkhodamohammadi , Inha Kang , Florian Kofler , Satoshi Kondo , Hugo Kuijf , Mingxing Li , Minh Huan Luu , Tomaž Martinčič , Pedro Morais , Mohamed A. Naser , Bruno Oliveira , David Owen , Subeen Pang , Jinah Park , Sung-Hong Park , Szymon Płotka , Elodie Puybareau , Nasir Rajpoot , Kanghyun Ryu , Numan Saeed , Adam Shephard , Pengcheng Shi , Dejan Štepec , Ronast Subedi , Guillaume Tochon , Helena R. Torres , Helene Urien , João L. Vilaça , Kareem Abdul Wahid , Haojie Wang , Jiacheng Wang , Liansheng Wang , Xiyue Wang , Benedikt Wiestler , Marek Wodzinski , Fangfang Xia , Juanying Xie , Zhiwei Xiong , Sen Yang , Yanwu Yang , Zixuan Zhao , Klaus Maier-Hein , Paul F. Jäger , Annette Kopp-Schneider , Lena Maier-Hein

Whole-slide image analysis via the means of computational pathology often relies on processing tessellated gigapixel images with only slide-level labels available. Applying multiple instance learning-based methods or transformer models is…

Computer Vision and Pattern Recognition · Computer Science 2023-10-20 Joshua Butke , Noriaki Hashimoto , Ichiro Takeuchi , Hiroaki Miyoshi , Koichi Ohshima , Jun Sakuma

Instance segmentation and classification of nuclei is an important task in computational pathology. We show that StarDist, a deep learning nuclei segmentation method originally developed for fluorescence microscopy, can be extended and…

Computer Vision and Pattern Recognition · Computer Science 2022-08-22 Martin Weigert , Uwe Schmidt

Hematoxylin and Eosin stained histopathology image analysis is essential for the diagnosis and study of complicated diseases such as cancer. Existing state-of-the-art approaches demand extensive amount of supervised training data from…

Computer Vision and Pattern Recognition · Computer Science 2017-12-15 Le Hou , Ayush Agarwal , Dimitris Samaras , Tahsin M. Kurc , Rajarsi R. Gupta , Joel H. Saltz

Cancer is one of the leading causes of death worldwide. Fast and safe early-stage, pre- and intra-operative diagnostics can significantly contribute to successful cancer identification and treatment. Artificial intelligence has played an…

Tissues and Organs · Quantitative Biology 2022-08-10 Marina Zajnulina

Histological staining is the gold standard for tissue examination in clinical pathology and life-science research, which visualizes the tissue and cellular structures using chromatic dyes or fluorescence labels to aid the microscopic…

Medical Physics · Physics 2023-03-07 Bijie Bai , Xilin Yang , Yuzhu Li , Yijie Zhang , Nir Pillar , Aydogan Ozcan

Automated skin lesion analysis is very crucial in clinical practice, as skin cancer is among the most common human malignancy. Existing approaches with deep learning have achieved remarkable performance on this challenging task, however,…

Computer Vision and Pattern Recognition · Computer Science 2019-09-06 Xueying Shi , Qi Dou , Cheng Xue , Jing Qin , Hao Chen , Pheng-Ann Heng

The MICCAI conference has encountered tremendous growth over the last years in terms of the size of the community, as well as the number of contributions and their technical success. With this growth, however, come new challenges for the…

The complexities inherent to leukemia, multifaceted cancer affecting white blood cells, pose considerable diagnostic and treatment challenges, primarily due to reliance on laborious morphological analyses and expert judgment that are…

Thyroid cancer is currently the fifth most common malignancy diagnosed in women. Since differentiation of cancer sub-types is important for treatment and current, manual methods are time consuming and subjective, automatic computer-aided…

Finding abnormal lymph nodes in radiological images is highly important for various medical tasks such as cancer metastasis staging and radiotherapy planning. Lymph nodes (LNs) are small glands scattered throughout the body. They are…

Computer Vision and Pattern Recognition · Computer Science 2023-07-31 Ke Yan , Dakai Jin , Dazhou Guo , Minfeng Xu , Na Shen , Xian-Sheng Hua , Xianghua Ye , Le Lu

The detection of blood disorders often hinges upon the quantification of specific blood cell types. Variations in cell counts may indicate the presence of pathological conditions. Thus, the significance of developing precise automatic…

Image and Video Processing · Electrical Eng. & Systems 2025-03-24 Davide Antonio Mura , Michela Pinna , Lorenzo Putzu , Andrea Loddo , Alessandra Perniciano , Olga Mulas , Cecilia Di Ruberto
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