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In this study, we present a novel clinical decision support system and discuss its interpretability-related properties. It combines a decision set of rules with a machine learning scheme to offer global and local interpretability. More…

Methodology · Statistics 2021-07-16 Francisco Valente , Simão Paredes , Jorge Henriques

Reproducibility is a key requirement for scientific progress. It allows the reproduction of the works of others, and, as a consequence, to fully trust the reported claims and results. In this work, we argue that, by facilitating…

Information Retrieval · Computer Science 2021-02-02 Alejandro Bellogín , Alan Said

The reproducibility of experiments is one of the main principles of the scientific method. However, numerical N-body experiments, especially those of planetary systems, are currently not reproducible. In the most optimistic scenario, they…

Earth and Planetary Astrophysics · Physics 2017-01-26 Hanno Rein , Daniel Tamayo

Discrete choice models (DCMs) have been widely utilized in various scientific fields, especially economics, for many years. These models consider a stochastic environment influencing each decision maker's choices. Extensive research has…

General Economics · Economics 2026-01-13 Amirreza Talebi

Robotic cell injection is used for automatically delivering substances into a cell and is an integral component of drug development, genetic engineering and many other areas of cell biology. Traditionally, the correctness of functionality…

Logic in Computer Science · Computer Science 2018-07-20 Adnan Rashid , Osman Hasan

Recent advancements in AI applications to healthcare have shown incredible promise in surpassing human performance in diagnosis and disease prognosis. With the increasing complexity of AI models, however, concerns regarding their opacity,…

Machine Learning · Computer Science 2023-08-17 Munib Mesinovic , Peter Watkinson , Tingting Zhu

Tools, models and statistical methods for signal processing and medical image analysis and training deep learning models to create research prototypes for eventual clinical applications are of special interest to the biomedical imaging…

Image and Video Processing · Electrical Eng. & Systems 2023-12-22 Pratik Shah , Jenna Lester , Jana G Deflino , Vinay Pai

Modelling and computational methods have been essential in advancing quantitative science, especially in the past two decades with the availability of vast amount of complex, voluminous, and heterogeneous data. In particular, there has been…

Multiagent Systems · Computer Science 2020-07-09 Affan Shoukat , Seyed M. Moghadas

The reproduction and replication of novel results has become a major issue for a number of scientific disciplines. In computer science and related computational disciplines such as systems biology, the issues closely revolve around the…

Software Engineering · Computer Science 2014-09-17 Tom Crick , Benjamin A. Hall , Samin Ishtiaq

Despite the advantages of using biodegradable metals in implant design, their uncontrolled degradation and release remain a challenge in practical applications. A validated computational model of the degradation process can facilitate the…

Computational Engineering, Finance, and Science · Computer Science 2021-07-28 Mojtaba Barzegari , Di Mei , Sviatlana V. Lamaka , Liesbet Geris

Multiscale models allow for the treatment of complex phenomena involving different scales, such as remodeling and growth of tissues, muscular activation, and cardiac electrophysiology. Numerous numerical approaches have been developed to…

Numerical Analysis · Mathematics 2018-06-28 Marco Favino , Alessio Quaglino , Sonia Pozzi , Rolf Krause , Igor Pivkin

Synthetic data has emerged as a powerful resource in life sciences, offering solutions for data scarcity, privacy protection and accessibility constraints. By creating artificial datasets that mirror the characteristics of real data, allows…

Simulations play a crucial role in the modern scientific process. Yet despite (or due to) this ubiquity, the Data Science community shares neither a comprehensive definition for a "high-quality" study nor a consolidated guide to designing…

Computation · Statistics 2025-05-16 Corrine F Elliott , James PC Duncan , Tiffany M Tang , Merle Behr , Karl Kumbier , Bin Yu

Machine learning is increasingly recognized as a promising technology in the biological, biomedical, and behavioral sciences. There can be no argument that this technique is incredibly successful in image recognition with immediate…

Nowadays, we are witnessing a wide adoption of Machine learning (ML) models in many safety-critical systems, thanks to recent breakthroughs in deep learning and reinforcement learning. Many people are now interacting with systems based on…

Software Engineering · Computer Science 2018-12-07 Houssem Ben Braiek , Foutse Khomh

Digital engineering has transformed the design and development process. However, the utility of digital engineering is fundamentally dependent on the assumption that a simulation provides information consistent with reality. This…

Computational Engineering, Finance, and Science · Computer Science 2025-08-01 Evan Taylor , Edward Louis , Gregory Mocko

Computational reproducibility is a growing problem that has been extensively studied among computational researchers and within the signal processing and machine learning research community. However, with the changing landscape of signal…

Signal Processing · Electrical Eng. & Systems 2022-02-16 Joseph Shenouda , Waheed U. Bajwa

Ensuring the reproducibility of scientific work is crucial as it allows the consistent verification of scientific claims and facilitates the advancement of knowledge by providing a reliable foundation for future research. However,…

Software Engineering · Computer Science 2025-04-14 Lázaro Costa , Susana Barbosa , Jácome Cunha

A large scientific community depends on the precise modelling of complex processes in particle cascades in various types of matter. These models are used most prevalently in cosmic-ray physics, astrophysical-neutrino physics, and gamma-ray…

Instrumentation and Methods for Astrophysics · Physics 2018-12-20 Ralph Engel , Dieter Heck , Tim Huege , Tanguy Pierog , Maximilian Reininghaus , Felix Riehn , Ralf Ulrich , Michael Unger , Darko Veberič

Cellular Agent-Based Models are commonly employed to describe a variety biological systems. Over the course of the past years, many modeling tools have emerged which solve particular research questions. In this short opinion piece, we argue…

Cell Behavior · Quantitative Biology 2025-11-18 Jonas Pleyer