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From a data perspective, the materials mechanics field is characterized by sparsity of available data, mainly due to the strong microstructure-sensitivity of properties like strength, fracture toughness, and fatigue limit. This requires…

Computational Physics · Physics 2024-11-19 Ronak Shoghi , Alexander Hartmaier

Advances in robotic control and sensing have propelled the rise of automated scientific laboratories capable of high-throughput experiments. However, automated scientific laboratories are currently limited by human intuition in their…

Machine Learning · Computer Science 2024-12-18 Saaketh Desai , Sadhvikas Addamane , Jeffrey Y. Tsao , Igal Brener , Laura P. Swiler , Remi Dingreville , Prasad P. Iyer

We introduce a high throughput 3D scanning solution specifically designed to precisely measure cattle phenotypes. This scanner leverages an array of depth sensors, i.e. time-of-flight (Tof) sensors, each governed by dedicated embedded…

Computer Vision and Pattern Recognition · Computer Science 2025-03-04 Gbenga Omotara , Seyed Mohamad Ali Tousi , Jared Decker , Derek Brake , Guilherme N. DeSouza

Real-time computer-aided diagnosis using artificial intelligence (AI), with images, can help oncologists diagnose cancer with high accuracy and in an early phase. We reviewed real-time AI-based analyzed images for decision-making in…

Image and Video Processing · Electrical Eng. & Systems 2025-03-17 Leila Bagheriye , Johan Kwisthout

Over nearly two decades, Differential Dynamic Microscopy (DDM) has become a standard technique for extracting dynamic correlation functions from time-lapse microscopy data, with applications spanning colloidal suspensions, polymer…

Soft Condensed Matter · Physics 2025-11-11 Enrico Lattuada , Fabian Krautgasser , Maxime Lavaud , Fabio Giavazzi , Roberto Cerbino

Whole slide imaging (WSI) has moved digital pathology closer to diagnostic practice in recent years. Due to the inherent tissue topography variability, accurate autofocusing remains a critical challenge for WSI and automated microscopy…

In computational digital pathology, accurate nuclear segmentation of Hematoxylin and Eosin (H&E) stained whole slide images (WSIs) is a critical step for many analyses and tissue characterizations. One popular deep learning-based nuclear…

Autonomous neutron spectroscopy must solve three distinct tasks: detection (where is the signal?), inference (which Hamiltonian governs it?), and refinement (what are the parameters?). No single controller solves all three equally well. We…

Materials Science · Physics 2026-04-28 William Ratcliff

Advanced microscopy and/or spectroscopy tools play indispensable role in nanoscience and nanotechnology research, as it provides rich information about the growth mechanism, chemical compositions, crystallography, and other important…

Frozen sectioning (FS) is the preparation method of choice for microscopic evaluation of tissues during surgical operations. The high speed of the procedure allows pathologists to rapidly assess the key microscopic features, such as tumour…

Modeling artificial scanning electron microscope (SEM) and scanning ion microscope images has recently become important. This is because of the need to provide repeatable images with a priori determined parameters. Modeled artificial images…

Instrumentation and Detectors · Physics 2015-05-19 Petr Cizmar , Andras E. Vladar , Michael T. Postek

Panoramic RGB-D cameras are known for their ability to produce high quality 3D scene reconstructions. However, operating these cameras involves manually selecting viewpoints and physically transporting the camera, making the generation of a…

Robotics · Computer Science 2025-07-30 Euijeong Lee , Kyung Min Han , Young J. Kim

We developed a rapid scanning optical microscope, termed "BlurryScope", that leverages continuous image acquisition and deep learning to provide a cost-effective and compact solution for automated inspection and analysis of tissue sections.…

Image and Video Processing · Electrical Eng. & Systems 2025-08-07 Michael John Fanous , Christopher Michael Seybold , Hanlong Chen , Nir Pillar , Aydogan Ozcan

Scanning Transmission Electron Microscopy (STEM) has become the main stay for materials characterization on atomic level, with applications ranging from visualization of localized and extended defects to mapping order parameter fields. In…

Instrumentation and Detectors · Physics 2019-01-15 Xin Li , Ondrej Dyck , Sergei V. Kalinin , Stephen Jesse

Image simulation remains under-exploited for the most widely used biological phase microscopy methods, because of difficulties in simulating partially coherent illumination. We describe an open-source toolbox, microlith…

Optics · Physics 2014-05-14 Shalin B. Mehta , Rudolf Oldenbourg

Automated experiments in 4D Scanning Transmission Electron Microscopy are implemented for rapid discovery of local structures, symmetry-breaking distortions, and internal electric and magnetic fields in complex materials. Deep kernel…

Materials Science · Physics 2022-04-22 Kevin M. Roccapriore , Ondrej Dyck , Mark P. Oxley , Maxim Ziatdinov , Sergei V. Kalinin

Driven by human ingenuity and creativity, the discovery of super-resolution techniques, which circumvent the classical diffraction limit of light, represent a leap in optical microscopy. However, the vast space encompassing all possible…

Optics · Physics 2024-12-17 Carla Rodríguez , Sören Arlt , Leonhard Möckl , Mario Krenn

Despite super-resolution fluorescence blinking microscopes break the diffraction limit, the intense phototoxic illumination and long-term image sequences thus far still pose to major challenges in visualizing live-organisms. Here, we…

The Probe-Particle Model combine theories designed for the simulation of scanning probe microscopy experiments, employing non-reactive, flexible tip apices to achieve sub-molecular resolution. In the article we present the latest version of…

Mesoscale and Nanoscale Physics · Physics 2024-07-02 Niko Oinonen , Aliaksandr V. Yakutovich , Aurelio Gallardo , Martin Ondracek , Prokop Hapala , Ondrej Krejci

Autonomous experimentation systems have been used to greatly advance the integrated computational materials engineering (ICME) paradigm. This paper outlines a framework that enables the design and selection of data collection workflows for…

Materials Science · Physics 2022-06-20 Rohan Casukhela , Sriram Vijayan , Joerg R. Jinschek , Stephen R. Niezgoda
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