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The SIR model is one of the most prototypical compartmental models in epidemiology. Generalizing this ordinary differential equation (ODE) framework into a spatially distributed partial differential equation (PDE) model is a considerable…

Quantitative Methods · Quantitative Biology 2024-07-11 Su Yang , Weiqi Chu , Panayotis Kevrekidis

This paper is concerned with a stochastic model for the spread of an SEIR (susceptible -> exposed (=latent) -> infective -> removed) epidemic with a contact tracing scheme, in which removed individuals may name some of their infectious…

Probability · Mathematics 2015-12-08 Frank G Ball , Edward S Knock , Philip D O'Neill

We present two epidemiological models, which extend the classical SEIR model by accounting for the effect of indiscriminate quarantining, isolation of infected individuals based on testing and the presence of asymptomatic individuals. Given…

Dynamical Systems · Mathematics 2020-11-30 Zuzana Chladná , Jana Kopfová , Dmitrii Rachinskii , Pavel Štepánek

We first propose a quantitative approach to detect high risk outbreaks of independent and coinfective SIR dynamics on three empirical networks: a school, a conference and a hospital contact network. This measurement is based on the k-means…

Populations and Evolution · Quantitative Biology 2021-09-15 Sina Sajjadi , Mohammad Reza Ejtehadi , Fakhteh Ghanbarnejad

We study a well mixed SIR epidemic model with heterogeneous susceptibility and infectivity, allowing for an arbitrary joint distribution of these traits. Using an exact final size formulation and a branching process approximation for early…

Populations and Evolution · Quantitative Biology 2026-01-06 Mohamed El Khalifi

The basic Susceptible-Infected-Recovered (SIR) model is extended to include effects of progressive social awareness, lockdowns and anthropogenic migration. It is found that social awareness can effectively contain the spread by lowering the…

Physics and Society · Physics 2021-06-01 R. Bhattacharyya , Partha Konar

Heterogeneity is an important property of any population experiencing a disease. Here we apply general methods of the theory of heterogeneous populations to the simplest mathematical models in epidemiology. In particular, an SIR…

Populations and Evolution · Quantitative Biology 2012-02-28 Artem S Novozhilov

Mathematical models of infectious diseases exhibit robust dynamics such as stable endemic or a disease-free equilibrium, or convergence of the solutions to periodic epidemic waves. The present work shows that the accuracy of such dynamics…

Applications · Statistics 2022-05-04 Hadeel AlQadi , Majid Bani-Yaghoub

In this work we performed a numerical study of an epidemic model that mimics the endemic state of whooping cough in the pre-vaccine era. We considered a stochastic SIR model on dynamical networks that involve local and global contacts among…

Physics and Society · Physics 2015-06-09 Martin Dottori , Gabriel Fabricius

We consider the edge-based compartmental models for infectious disease spread introduced in Part I. These models allow us to consider standard SIR diseases spreading in random populations. In this paper we show how to handle deviations of…

Populations and Evolution · Quantitative Biology 2015-09-03 Joel C. Miller , Erik M. Volz

We use daily data from Lombardy, the Italian region most affected by the COVID-19 outbreak, to calibrate a SIR model individually on each municipality. These are all covered by the same health system and, in the post-lockdown phase we focus…

Populations and Evolution · Quantitative Biology 2020-04-20 Pietro Battiston , Simona Gamba

We study the qualitative properties of a spatial diffusive heterogeneous SIR model, that appears in mathematical epidemiology to describe the spread of an infectious disease in a population. The model we consider consists in a system of…

Analysis of PDEs · Mathematics 2020-05-15 Romain Ducasse

Socio-demographic factors influence social contact patterns and play a fundamental role in shaping the transmission dynamics of infectious diseases. However, compartment-based models of infectious disease dynamics commonly consider the…

Physics and Society · Physics 2026-05-15 Vincent X. Lomas , Tim Chambers , Leighton Watson , Michael Plank

Infectious disease dynamics operate across multiple biological scales, with within-host viral dynamics being a key driver of between-host transmission. However, while models that explicitly link these scales exist, none have been developed…

Applications · Statistics 2026-04-23 Dylan J. Morris , Lauren Kennedy , Andrew J. Black

We formulate an age-structured nonlinear partial differential equation model that features short-term immigration effects in a population. Individuals can immigrate into the population as any of the three stages in the model: susceptible,…

Populations and Evolution · Quantitative Biology 2019-08-07 Fabio Sanchez , Juan Gabriel Calvo

We consider a Susceptible-Infective-Recovered (SIR) model, where the mechanism for the renewal of susceptibles is demographic, on a ring with next nearest neighbour interactions, and a family of correlated pair approximations (CPA),…

Populations and Evolution · Quantitative Biology 2013-06-04 Jerome Benoit , Ana Nunes , Margarida Telo da Gama

The generation interval is the time between the infection time of an infected person and the infection time of his or her infector. Probability density functions for generation intervals have been an important input for epidemic models and…

Quantitative Methods · Quantitative Biology 2023-10-24 Eben Kenah , Marc Lipsitch , James M. Robins

Attempts to curb the spread of coronavirus by introducing strict quarantine measures apparently have different effect in different countries: while the number of new cases has reportedly decreased in China and South Korea, it still exhibit…

Populations and Evolution · Quantitative Biology 2020-03-24 Vitaly Volpert , Malay Banerjee , Sergei Petrovskii

We have derived the governing equations for an SIR model with delay terms in both the infectivity and recovery of the disease. The equations are derived by modelling the dynamics as a continuous time random walk, where individuals move…

Dynamical Systems · Mathematics 2024-10-14 Christopher N. Angstmann , Stuart-James M. Burney , Anna V. McGann , Zhuang Xu

Multiple viruses are widely studied because of their negative effect on the health of host as well as on whole population. The dynamics of coinfection is important in this case. We formulated a SIR model that describes the coinfection of…

Dynamical Systems · Mathematics 2019-05-14 Samia Ghersheen , Vladimir Kozlov , Vladimir G. Tkachev , Uno Wennergren