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Depression is a widespread mental disorder that affects millions worldwide. While automated depression assessment shows promise, most studies rely on limited or non-clinically validated data, and often prioritize complex model design over…

Computation and Language · Computer Science 2025-08-07 Zhuang Chen , Guanqun Bi , Wen Zhang , Jiawei Hu , Aoyun Wang , Xiyao Xiao , Kun Feng , Minlie Huang

Current psychiatric research is in crisis. In this review I will describe the causes of this crisis and highlight recent efforts to overcome current challenges. One particularly promising approach is the emerging field of computational…

Neurons and Cognition · Quantitative Biology 2013-03-25 Thomas V. Wiecki

Computational mental health research develops models to predict and understand psychological phenomena, but often relies on inappropriate measures of psychopathology constructs, undermining validity. We identify three key issues: (1)…

Human-Computer Interaction · Computer Science 2025-04-22 Chen Shani , Elizabeth C. Stade

Bipolar disorder is a mental health disorder that causes mood swings that range from depression to mania. Diagnosis of bipolar disorder is usually done based on patient interviews, and reports obtained from the caregivers of the patients.…

Computation and Language · Computer Science 2021-12-20 Pınar Baki

Mental disorders pose a global challenge, aggravated by the shortage of qualified mental health professionals. Mental disorder prediction from social media posts by current LLMs is challenging due to the complexities of sequential text data…

Computation and Language · Computer Science 2024-10-08 Raja Kumar , Kishan Maharaj , Ashita Saxena , Pushpak Bhattacharyya

Decision-making related to health is complex. Machine learning (ML) and patient generated data can identify patterns and insights at the individual level, where human cognition falls short, but not all ML-generated information is of equal…

Applications · Statistics 2021-01-15 Elliot G Mitchell , Esteban G Tabak , Matthew E Levine , Lena Mamykina , David J Albers

Text-based conversational agents (CAs) are increasingly used in mental health, yet evaluation practices remain fragmented. We conducted a PRISMA-guided systematic review (May-June 2024) across ACM Digital Library, Scopus, and PsycINFO. From…

Human-Computer Interaction · Computer Science 2026-02-23 Jiangtao Gong , Xiao Wen , Fengyi Tao , Xinqi Wang , Xixi Yang , Yangrong Tang

Development of interpretable machine learning models for clinical healthcare applications has the potential of changing the way we understand, treat, and ultimately cure, diseases and disorders in many areas of medicine. These models can…

Machine Learning · Computer Science 2019-08-06 Qingzhu Gao , Humberto Gonzalez , Parvez Ahammad

Personalized medicine aims at identifying best treatments for a patient with given characteristics. It has been shown in the literature that these methods can lead to great improvements in medicine compared to traditional methods…

Machine Learning · Statistics 2018-11-26 Oleg Sysoev , Krzysztof Bartoszek , Eva-Charlotte Ekstrom , Katarina Ekholm Selling

Cognitive diagnosis has been developed for decades as an effective measurement tool to evaluate human cognitive status such as ability level and knowledge mastery. It has been applied to a wide range of fields including education, sport,…

Artificial Intelligence · Computer Science 2024-07-09 Fei Wang , Weibo Gao , Qi Liu , Jiatong Li , Guanhao Zhao , Zheng Zhang , Zhenya Huang , Mengxiao Zhu , Shijin Wang , Wei Tong , Enhong Chen

Three-way decision is widely applied with rough set theory to learn classification or decision rules. The approaches dealing with complete information are well established in the literature, including the two complementary computational and…

Artificial Intelligence · Computer Science 2025-12-29 Junfang Luo , Mengjun Hu , Keyun Qin

Mental health issues differ widely among individuals, with varied signs and symptoms. Recently, language-based assessments have shown promise in capturing this diversity, but they require a substantial sample of words per person for…

Computation and Language · Computer Science 2024-05-17 Vasudha Varadarajan , Sverker Sikström , Oscar N. E. Kjell , H. Andrew Schwartz

This study integrates causal inference, graph analysis, temporal complexity measures, and machine learning to examine whether individual symptom trajectories can reveal meaningful diagnostic patterns. Testing on a longitudinal dataset of…

Applications · Statistics 2025-07-22 Eleonora Vitanza , Pietro DeLellis , Chiara Mocenni , Manuel Ruiz Marin

Multimodal sentiment analysis (MSA) aims to understand human emotions by integrating information from multiple modalities, such as text, audio, and visual data. However, existing methods often suffer from spurious correlations both within…

Machine Learning · Computer Science 2026-05-21 Menghua Jiang , Yuxia Lin , Baoliang Chen , Haifeng Hu , Yuncheng Jiang , Sijie Mai

Passively collected behavioral health data from ubiquitous sensors holds significant promise to provide mental health professionals insights from patient's daily lives; however, developing analysis tools to use this data in clinical…

Meta-analysis is a systematic approach for understanding a phenomenon by analyzing the results of many previously published experimental studies. It is central to deriving conclusions about the summary effect of treatments and interventions…

Computers and Society · Computer Science 2021-04-13 Lu Cheng , Dmitriy A. Katz-Rogozhnikov , Kush R. Varshney , Ioana Baldini

This paper describes a novel approach to medical diagnosis based on the SP theory of computing and cognition. The main attractions of this approach are: a format for representing diseases that is simple and intuitive; an ability to cope…

Artificial Intelligence · Computer Science 2014-09-30 J. Gerard Wolff

Clinical decision support systems combine knowledge and data from a variety of sources, represented by quantitative models based on stochastic methods, or qualitative based rather on expert heuristics and deductive reasoning. At the same…

Artificial Intelligence · Computer Science 2020-01-22 Ying Shen , Jacquet-Andrieu Armelle , Joël Colloc

The concept of care pathways is increasingly being used to enhance the quality of care and to optimize the use of resources for health care. Nevertheless, recommendations regarding the sequence of care are mostly based on consensus-based…

Methodology · Statistics 2022-09-12 Laura Savaré , Francesca Ieva , Giovanni Corrao , Antonio Lora

We propose a clinical decision support system (CDSS) for mental health diagnosis that combines the strengths of large language models (LLMs) and constraint logic programming (CLP). Having a CDSS is important because of the high complexity…

Artificial Intelligence · Computer Science 2025-02-24 Brian Hyeongseok Kim , Chao Wang
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