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In this article, we use the illness-death model to present a mathematical framework for studying the compression of morbidity (COM) hypothesis. It turns out that questions about COM are completely determined by the transition rates in the…

Quantitative Methods · Quantitative Biology 2018-07-31 Ralph Brinks

Mortality forecasting plays a pivotal role in insurance and financial risk management of life insurers, pension funds, and social securities. Mortality data is usually high-dimensional in nature and favors factor model approaches to…

Applications · Statistics 2021-12-10 Lingyu He , Fei Huang , Yanrong Yang

Index-based hedging solutions are used to transfer the longevity risk to the capital markets. However, mismatches between the liability of the hedger and the hedging instrument cause longevity basis risk. Therefore, an appropriate…

Risk Management · Quantitative Finance 2021-01-19 Selin Özen , Şule Şahin

To build a dementia classification model for middle-aged and elderly Brazilians, implemented in Python, combining variable selection and multivariable analysis, using low-cost variables with modification potential. Observational study with…

Machine Learning · Computer Science 2026-02-20 F. S. Menezes , M. C. F. G. Barretto , E. Q. C. Garcia , T. A. E. Ferreira , J. G. Alvez

Assuming the deleterious mutations in the Penna ageing model to affect mainly the young ages, we get an enhanced mortality at very young age, followed by a minimum of the mortality, and then the usual exponential increase of mortality with…

Populations and Evolution · Quantitative Biology 2007-08-28 D. Stauffer , S. Moss de Oliveira

The Healthy Life Years Lost Methodology (HLYL) is introduced to model and estimate the Health Expenditure in Japan in 2011. The HLYL theory and estimation methods are presented in our books in the Springer Series on Demographic Methods and…

Other Statistics · Statistics 2019-03-28 Christos H Skiadas , Charilaos Skiadas

Demographic projections of future mortality rates involve a high level of uncertainty and require stochastic mortality models. The current paper investigates forward mortality models driven by a (possibly infinite dimensional) Wiener…

Probability · Mathematics 2025-11-21 Stefan Tappe , Stefan Weber

The task of modeling claim severities is addressed when data is not consistent with the classical regression assumptions. This framework is common in several lines of business within insurance and reinsurance, where catastrophic losses or…

Statistics Theory · Mathematics 2022-04-01 Martin Bladt , Jorge Yslas

In recent we introduced, developed and established a new concept, model, methodology and principle for studying human longevity in terms of demographic basis. We call the new model the "Weon model", which is a general model modified from…

Populations and Evolution · Quantitative Biology 2007-05-23 Byung Mook Weon

Multimorbidity in older adults is common, heterogeneous, and highly dynamic, and it is strongly associated with disability and increased healthcare utilization. However, existing approaches to studying multimorbidity trajectories are…

In this work we present a spatial approach to model and investigate mortality data referenced over a Lexis structure. We decompose the force of mortality into two interpretable components: a Markov random field, smooth with respect to time,…

Applications · Statistics 2018-10-23 Fabio Divino , Denekew Bitew Belay , Nico Keilman , Arnoldo Frigessi

Designing proper treatment plans to manage diabetes requires health practitioners to pay heed to the individuals remaining life along with the comorbidities affecting them. Older adults with Type 2 Diabetes Mellitus (T2DM) are prone to…

Machine Learning · Computer Science 2024-02-20 Ruchika Desure , Gutha Jaya Krishna

Multiple cause-of-death data provides a valuable source of information that can be used to enhance health standards by predicting health related trajectories in societies with large populations. These data are often available in large…

Computation and Language · Computer Science 2017-05-11 Hamid Reza Hassanzadeh , Ying Sha , May D. Wang

Age-dependent dynamics is an important characteristic of many infectious diseases. Age-group epidemic models describe the infection dynamics in different age-groups by allowing to set distinct parameter values for each. However, such models…

Methodology · Statistics 2017-07-17 Rami Yaari , Itai Dattner , Amit Huppert

Age-disaggregated health data is crucial for effective public health planning and monitoring. Monitoring under-five mortality, for example, requires highly detailed age data since the distribution of potential causes of death varies…

Applications · Statistics 2023-02-23 Shuxian Fan , Li Liu , Jamie Perin , Tyler H. McCormick

The face is a rich source of information that can be utilized to infer a person's biological age, sex, phenotype, genetic defects, and health status. All of these factors are relevant for predicting an individual's remaining lifespan. In…

Computer Vision and Pattern Recognition · Computer Science 2023-01-20 Amir Fekrazad

In this paper we introduce a mixture cure model with a linear hazard rate regression model for the event times. Cure models are statistical models for event times that take into account that a fraction of the population might never…

Statistics Theory · Mathematics 2020-11-26 Emil Aas Stoltenberg

This study introduces an innovative methodology for mortality forecasting, which integrates signature-based methods within the functional data framework of the Hyndman-Ullah (HU) model. This new approach, termed the Hyndman-Ullah with…

Methodology · Statistics 2025-01-29 Zhong Jing Yap , Dharini Pathmanathan , Sophie Dabo-Niang

The use of artificial intelligence in clinical care to improve decision support systems is increasing. This is not surprising since, by its very nature, the practice of medicine consists of making decisions based on observations from…

Quantitative Methods · Quantitative Biology 2019-05-03 Isaac Mativo , Yelena Yesha , Michael Grasso , Tim Oates , Qian Zhu

Data on functional disability are of widespread policy interest in the United States, especially with respect to planning for Medicare and Social Security for a growing population of elderly adults. We consider an extract of functional…

Applications · Statistics 2009-09-29 Elena A. Erosheva , Stephen E. Fienberg , Cyrille Joutard