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Single-cell RNA sequencing (scRNA-seq) allows transcriptional profiling, and cell-type annotation of individual cells. However, sample preparation in typical scRNA-seq experiments often homogenizes the samples, thus spatial locations of…

Applications · Statistics 2024-08-28 Junhao Zhu , Kevin Zhang , Dehan Kong , Zhaolei Zhang

The explicit neural radiance field (NeRF) has gained considerable interest for its efficient training and fast inference capabilities, making it a promising direction such as virtual reality and gaming. In particular, PlenOctree (POT)[1],…

Computer Vision and Pattern Recognition · Computer Science 2023-07-31 Haotian Bai , Yiqi Lin , Yize Chen , Lin Wang

In this paper we present DOT (Dynamic Object Tracking), a front-end that added to existing SLAM systems can significantly improve their robustness and accuracy in highly dynamic environments. DOT combines instance segmentation and…

Computer Vision and Pattern Recognition · Computer Science 2020-10-02 Irene Ballester , Alejandro Fontan , Javier Civera , Klaus H. Strobl , Rudolph Triebel

Single-cell RNA-seq (scRNA-seq) technology is a powerful tool for unraveling the complexity of biological systems. One of essential and fundamental tasks in scRNA-seq data analysis is Cell Type Annotation (CTA). In spite of tremendous…

Genomics · Quantitative Biology 2024-11-04 Chaochen Wu , Meiyun Zuo , Lei Xie

Single-cell RNA-sequencing technologies may provide valuable insights to the understanding of the composition of different cell types and their functions within a tissue. Recent technologies such as spatial transcriptomics, enable the…

Applications · Statistics 2023-05-16 Arhit Chakrabarti , Yang Ni , Bani K. Mallick

Few-Shot Remote Sensing Scene Classification (FS-RSSC) presents the challenge of classifying remote sensing images with limited labeled samples. Existing methods typically emphasize single-modal feature learning, neglecting the potential…

Computer Vision and Pattern Recognition · Computer Science 2025-03-20 Zhong Ji , Ci Liu , Jingren Liu , Chen Tang , Yanwei Pang , Xuelong Li

Dynamic optical coherence tomography (DOCT) statistically analyzes fluctuations in time-sequential OCT signals, enabling label-free and three-dimensional visualization of intratissue and intracellular activities. Current DOCT methods, such…

Diffuse Optical Tomography (DOT) is an emerging technology in medical imaging which employs light in the NIR spectrum to estimate the distribution of optical coefficients in biological tissues for diagnostic and monitoring purposes. DOT…

Numerical Analysis · Mathematics 2022-05-27 Alessandro Benfenati , Giuseppe Bisazza , Paola Causin

Cellular identity and function are linked to both their intrinsic genomic makeup and extrinsic spatial context within the tissue microenvironment. Spatial transcriptomics (ST) offers an unprecedented opportunity to study this, providing in…

Machine Learning · Computer Science 2026-02-16 Rui Yan , Xiaohan Xing , Xun Wang , Zixia Zhou , Md Tauhidul Islam , Lei Xing

Spatial transcriptomics (ST) provides spatially resolved measurements of gene expression, enabling characterization of the molecular landscape of human tissue beyond histological assessment as well as localized readouts that can be aligned…

Computer Vision and Pattern Recognition · Computer Science 2026-02-17 Konstantin Hemker , Andrew H. Song , Cristina Almagro-Pérez , Guillaume Jaume , Sophia J. Wagner , Anurag Vaidya , Nikola Simidjievski , Mateja Jamnik , Faisal Mahmood

The development of single-cell and spatial transcriptomics has revolutionized our capacity to investigate cellular properties, functions, and interactions in both cellular and spatial contexts. However, the analysis of single-cell and…

Genomics · Quantitative Biology 2024-12-09 Shuang Ge , Shuqing Sun , Huan Xu , Qiang Cheng , Zhixiang Ren

We introduce a novel gene regulatory network (GRN) inference method that integrates optimal transport (OT) with a deep-learning structural inference model. Advances in next-generation sequencing enable detailed yet destructive gene…

Computational Engineering, Finance, and Science · Computer Science 2024-09-24 Tsz Pan Tong , Aoran Wang , George Panagopoulos , Jun Pang

As a vital problem in pattern analysis and machine intelligence, Unsupervised Domain Adaptation (UDA) attempts to transfer an effective feature learner from a labeled source domain to an unlabeled target domain. Inspired by the success of…

Computer Vision and Pattern Recognition · Computer Science 2024-08-14 Ren Chuan-Xian , Zhai Yi-Ming , Luo You-Wei , Yan Hong

In this work we present the first application of software-defined optoelectronics (SDO) for bidimensional optoacoustic tomography (OAT). The SDO concept refers to optoelectronic systems where the functionality associated with the…

Signal Processing · Electrical Eng. & Systems 2023-05-10 Roberto Insabella , Martin Gonzalez , Lucas Riobo , Klaus Hass , Francisco Veiras

Diffractive optical neural networks (DONNs) have been emerging as a high-throughput and energy-efficient hardware platform to perform all-optical machine learning (ML) in machine vision systems. However, the current demonstrated…

Machine Learning · Computer Science 2023-02-23 Ruiyang Chen , Yingheng Tang , Jianzhu Ma , Weilu Gao

Inferring spatially resolved gene expression from histology images offers a cost-effective complement to spatial transcriptomics (ST). However, existing methods reduce this task to a simple morphology-to-expression mapping, where visual…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Junchao Zhu , Ruining Deng , Junlin Guo , Tianyuan Yao , Chongyu Qu , Juming Xiong , Zhengyi Lu , Yanfan Zhu , Marilyn Lionts , Yuechen Yang , Yu Wang , Shilin Zhao , Haichun Yang , Yuankai Huo

Historically, the majority of statistical association methods have been designed assuming availability of SNP-level information. However, modern genetic and sequencing data present new challenges to access and sharing of genotype-phenotype…

Genomics · Quantitative Biology 2020-07-01 Olga A Vsevolozhskaya , Min Shi , Fengjiao Hu , Dmitri V Zaykin

Cross-city transfer improves prediction in label-scarce cities by leveraging labeled data from other cities, but it becomes challenging when cities adopt incompatible partitions and no ground-truth region correspondences exist. Existing…

Machine Learning · Computer Science 2026-05-12 Yuyao Wang , Min Yang , Meng Chen , Weiming Huang , Yilong Yin , Yongshun Gong

Understanding the dynamic nature of biological systems is fundamental to deciphering cellular behavior, developmental processes, and disease progression. Single-cell RNA sequencing (scRNA-seq) has provided static snapshots of gene…

Quantitative Methods · Quantitative Biology 2025-05-02 Zhenyi Zhang , Yuhao Sun , Qiangwei Peng , Tiejun Li , Peijie Zhou

Light scattering by tissue severely limits how deep beneath the surface one can image, and the spatial resolution one can obtain from these images. Diffuse optical tomography (DOT) is one of the most powerful techniques for imaging deep…

Image and Video Processing · Electrical Eng. & Systems 2021-05-31 Yongyi Zhao , Ankit Raghuram , Hyun K. Kim , Andreas H. Hielscher , Jacob T. Robinson , Ashok Veeraraghavan
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