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Microscopy data collections are becoming larger and more frequent. Accurate and precise quantitative analysis tools like cell instance segmentation are necessary to benefit from them. This is challenging due to the variability in the data,…

Computer Vision and Pattern Recognition · Computer Science 2024-02-28 Ram J. Zaveri , Voke Brume , Gianfranco Doretto

Automatic cell segmentation in microscopy images works well with the support of deep neural networks trained with full supervision. Collecting and annotating images, though, is not a sustainable solution for every new microscopy database…

Computer Vision and Pattern Recognition · Computer Science 2020-07-06 Youssef Dawoud , Julia Hornauer , Gustavo Carneiro , Vasileios Belagiannis

Deep neural networks have become the go-to method for biomedical instance segmentation. Generalist models like Cellpose demonstrate state-of-the-art performance across diverse cellular data, though their effectiveness often degrades on…

Computer Vision and Pattern Recognition · Computer Science 2025-08-18 Fabian H. Reith , Jannik Franzen , Dinesh R. Palli , J. Lorenz Rumberger , Dagmar Kainmueller

Accurate segmentation of tissue in histopathological images can be very beneficial for defining regions of interest (ROI) for streamline of diagnostic and prognostic tasks. Still, adapting to different domains is essential for…

Image and Video Processing · Electrical Eng. & Systems 2023-03-10 Saul Fuster , Farbod Khoraminia , Trygve Eftestøl , Tahlita C. M. Zuiverloon , Kjersti Engan

The most popular networks used for cell segmentation (e.g. Cellpose, Stardist, HoverNet,...) rely on a prediction of a distance map. It yields unprecedented accuracy but hinges on fully annotated datasets. This is a serious limitation to…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Clément Cazorla , Nathanaël Munier , Renaud Morin , Pierre Weiss

Instance segmentation is a computer vision task where separate objects in an image are detected and segmented. State-of-the-art deep neural network models require large amounts of labeled data in order to perform well in this task. Making…

Computer Vision and Pattern Recognition · Computer Science 2022-02-21 Tuomas Sormunen , Arttu Lämsä , Miguel Bordallo Lopez

Nucleus instance segmentation from histopathology images suffers from the extremely laborious and expert-dependent annotation of nucleus instances. As a promising solution to this task, annotation-efficient deep learning paradigms have…

Computer Vision and Pattern Recognition · Computer Science 2024-02-29 Yu Ming , Zihao Wu , Jie Yang , Danyi Li , Yuan Gao , Changxin Gao , Gui-Song Xia , Yuanqing Li , Li Liang , Jin-Gang Yu

Image segmentation is a fundamental problem in biomedical image analysis. Recent advances in deep learning have achieved promising results on many biomedical image segmentation benchmarks. However, due to large variations in biomedical…

Computer Vision and Pattern Recognition · Computer Science 2017-06-16 Lin Yang , Yizhe Zhang , Jianxu Chen , Siyuan Zhang , Danny Z. Chen

Detecting and segmenting object instances is a common task in biomedical applications. Examples range from detecting lesions on functional magnetic resonance images, to the detection of tumours in histopathological images and extracting…

Computer Vision and Pattern Recognition · Computer Science 2021-04-12 Tim Prangemeier , Christoph Reich , Heinz Koeppl

We propose a new method that employs transfer learning techniques to effectively correct sampling selection errors introduced by sparse annotations during supervised learning for automated tumor segmentation. The practicality of current…

Interactive segmentation uses real-time user inputs, such as mouse clicks, to iteratively refine model predictions. Although not originally designed to address distribution shifts, this paradigm naturally lends itself to such challenges. In…

Computer Vision and Pattern Recognition · Computer Science 2026-04-22 Wentian Xu , Ziyun Liang , Harry Anthony , Yasin Ibrahim , Felix Cohen , Guang Yang , Konstantinos Kamnitsas

Cell microscopy data are abundant; however, corresponding segmentation annotations remain scarce. Moreover, variations in cell types, imaging devices, and staining techniques introduce significant domain gaps between datasets. As a result,…

Machine Learning · Computer Science 2026-01-27 Rüveyda Yilmaz , Zhu Chen , Yuli Wu , Johannes Stegmaier

Few-shot segmentation performance declines substantially when facing images from a domain different than the training domain, effectively limiting real-world use cases. To alleviate this, recently cross-domain few-shot segmentation (CD-FSS)…

Computer Vision and Pattern Recognition · Computer Science 2024-05-20 Jonas Herzog

Semantic segmentation is a critical step in automated image interpretation and analysis where pixels are classified into one or more predefined semantically meaningful classes. Deep learning approaches for semantic segmentation rely on…

Computer Vision and Pattern Recognition · Computer Science 2023-07-10 Tushar Kataria , Beatrice Knudsen , Shireen Elhabian

Segmentation is essential for medical image analysis tasks such as intervention planning, therapy guidance, diagnosis, treatment decisions. Deep learning is becoming increasingly prominent for segmentation, where the lack of annotations,…

Computer Vision and Pattern Recognition · Computer Science 2019-03-19 Firat Ozdemir , Zixuan Peng , Christine Tanner , Philipp Fuernstahl , Orcun Goksel

Cell instance segmentation is a fundamental task in digital pathology with broad clinical applications. Recently, vision foundation models, which are predominantly based on Vision Transformers (ViTs), have achieved remarkable success in…

Computer Vision and Pattern Recognition · Computer Science 2025-04-02 Yang Yang , Xijie Xu , Yixun Zhou , Jie Zheng

We describe a simple method for unsupervised domain adaptation, whereby the discrepancy between the source and target distributions is reduced by swapping the low-frequency spectrum of one with the other. We illustrate the method in…

Computer Vision and Pattern Recognition · Computer Science 2020-04-14 Yanchao Yang , Stefano Soatto

Deep learning-based diagnostic models often suffer performance drops due to distribution shifts between training (source) and test (target) domains. Collecting and labeling sufficient target domain data for model retraining represents an…

Computer Vision and Pattern Recognition · Computer Science 2025-07-02 Yaofei Duan , Yuhao Huang , Xin Yang , Luyi Han , Xinyu Xie , Zhiyuan Zhu , Ping He , Ka-Hou Chan , Ligang Cui , Sio-Kei Im , Dong Ni , Tao Tan

Animal behavior analysis plays a crucial role in various fields, such as life science and biomedical research. However, the scarcity of available data and the high cost associated with obtaining a large number of labeled datasets pose…

Computer Vision and Pattern Recognition · Computer Science 2023-12-14 Chen Yang , Jeremy Forest , Matthew Einhorn , Thomas A. Cleland

Recent trends in cell segmentation have shifted towards universal models to handle diverse cell morphologies and imaging modalities. However, for continuously emerging cell types and imaging techniques, these models still require hundreds…

Computer Vision and Pattern Recognition · Computer Science 2024-12-03 Peilin Zhou , Bo Du , Yongchao Xu
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