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Related papers: CellTranspose: Few-shot Domain Adaptation for Cell…

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Supervised learning is well-known to fail at generalization under distribution shifts. In typical clinical settings, the source data is inaccessible and the target distribution is represented with a handful of samples: adaptation can only…

Computer Vision and Pattern Recognition · Computer Science 2022-05-18 Mathilde Bateson , Hervé Lombaert , Ismail Ben Ayed

Segmentation is a crucial analysis task in biomedical imaging. Given the diverse experimental settings in this field, the lack of generalization limits the use of deep learning in practice. Domain adaptation is a promising remedy: it…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Anwai Archit , Constantin Pape

Medical image annotation is a major hurdle for developing precise and robust machine learning models. Annotation is expensive, time-consuming, and often requires expert knowledge, particularly in the medical field. Here, we suggest using…

Computer Vision and Pattern Recognition · Computer Science 2020-09-28 Holger R Roth , Dong Yang , Ziyue Xu , Xiaosong Wang , Daguang Xu

Continual Test-Time Adaptation (CTTA) enables pre-trained models to adapt to continuously evolving domains. Existing methods have improved robustness but typically rely on fixed or batch-level thresholds, which cannot account for varying…

Computer Vision and Pattern Recognition · Computer Science 2025-12-10 Seunghwan Lee , Inyoung Jung , Hojoon Lee , Eunil Park , Sungeun Hong

Cellular nuclei recognition serves as a fundamental and essential step in the workflow of digital pathology. However, with disparate source organs and staining procedures among histology image clusters, the scanned tiles inherently conform…

Quantitative Methods · Quantitative Biology 2024-07-22 Jianan Fan , Dongnan Liu , Canran Li , Hang Chang , Heng Huang , Filip Braet , Mei Chen , Weidong Cai

We propose a test-time adaptation method for cross-domain image segmentation. Our method is simple: Given a new unseen instance at test time, we adapt a pre-trained model by conducting instance-specific BatchNorm (statistics) calibration.…

Computer Vision and Pattern Recognition · Computer Science 2022-03-31 Yuliang Zou , Zizhao Zhang , Chun-Liang Li , Han Zhang , Tomas Pfister , Jia-Bin Huang

Microscopy images from different imaging conditions, organs, and tissues often have numerous cells with various shapes on a range of backgrounds. As a result, designing a deep learning model to count cells in a source domain becomes…

Computer Vision and Pattern Recognition · Computer Science 2023-03-21 Zuhui Wang

Instance segmentation enables the analysis of spatial and temporal properties of cells in microscopy images by identifying the pixels belonging to each cell. However, progress is constrained by the scarcity of high-quality labeled…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Kaden Stillwagon , Alexandra Dunnum VandeLoo , Benjamin Magondu , Craig R. Forest

Although recent neural models for coreference resolution have led to substantial improvements on benchmark datasets, transferring these models to new target domains containing out-of-vocabulary spans and requiring differing annotation…

Computation and Language · Computer Science 2023-06-01 Nupoor Gandhi , Anjalie Field , Emma Strubell

Few-shot segmentation aims to train a segmentation model that can fast adapt to a novel task for which only a few annotated images are provided. Most recent models have adopted a prototype-based paradigm for few-shot inference. These…

Computer Vision and Pattern Recognition · Computer Science 2024-01-19 Li Guo , Haoming Liu , Yuxuan Xia , Chengyu Zhang , Xiaochen Lu

In interactive object segmentation a user collaborates with a computer vision model to segment an object. Recent works employ convolutional neural networks for this task: Given an image and a set of corrections made by the user as input,…

Computer Vision and Pattern Recognition · Computer Science 2020-11-10 Theodora Kontogianni , Michael Gygli , Jasper Uijlings , Vittorio Ferrari

An often overlooked problem in medical image segmentation research is the effective selection of training subsets to annotate from a complete set of unlabelled data. Many studies select their training sets at random, which may lead to…

Computer Vision and Pattern Recognition · Computer Science 2025-03-24 Stephen Lloyd-Brown , Susan Francis , Caroline Hoad , Penny Gowland , Karen Mullinger , Andrew French , Xin Chen

Minimization of distribution matching losses is a principled approach to domain adaptation in the context of image classification. However, it is largely overlooked in adapting segmentation networks, which is currently dominated by…

Computer Vision and Pattern Recognition · Computer Science 2021-11-29 Georg Pichler , Jose Dolz , Ismail Ben Ayed , Pablo Piantanida

Increasing data set sizes of 3D microscopy imaging experiments demand for an automation of segmentation processes to be able to extract meaningful biomedical information. Due to the shortage of annotated 3D image data that can be used for…

Image and Video Processing · Electrical Eng. & Systems 2022-02-02 Dennis Eschweiler , Richard S. Smith , Johannes Stegmaier

Generalist biomedical image segmentation models such as Cellpose are increasingly applied across diverse imaging modalities and cell types. However, two critical challenges remain underexplored: (1) the extent of training data redundancy…

Computer Vision and Pattern Recognition · Computer Science 2025-11-10 Shuo Zhao , Jianxu Chen

Interactive segmentation enables clinicians to guide annotation, but existing zero-shot models like nnInteractive fail to consistently reach expert-level performance across diverse medical imaging tasks. Because annotation campaigns produce…

Computer Vision and Pattern Recognition · Computer Science 2026-03-09 Parhom Esmaeili , Chayanin Tangwiriyasakul , Eli Gibson , Sebastien Ourselin , M. Jorge Cardoso

Accurate segmentation of organelle instances from electron microscopy (EM) images plays an essential role in many neuroscience researches. However, practical scenarios usually suffer from high annotation costs, label scarcity, and large…

Computer Vision and Pattern Recognition · Computer Science 2024-04-02 Dafei Qiu , Shan Xiong , Jiajin Yi , Jialin Peng

Predicting drug response in patients from preclinical data remains a major challenge in precision oncology due to the substantial biological gap between in vitro cell lines and patient tumors. Rather than aiming to improve absolute in vitro…

Machine Learning · Computer Science 2026-03-18 Camille Jimenez Cortes , Philippe Lalanda , German Vega

Despite deep convolutional neural networks achieved impressive progress in medical image computing and analysis, its paradigm of supervised learning demands a large number of annotations for training to avoid overfitting and achieving…

Computer Vision and Pattern Recognition · Computer Science 2020-12-11 Liyan Sun , Chenxin Li , Xinghao Ding , Yue Huang , Guisheng Wang , Yizhou Yu

We introduce two criteria to regularize the optimization involved in learning a classifier in a domain where no annotated data are available, leveraging annotated data in a different domain, a problem known as unsupervised domain…

Computer Vision and Pattern Recognition · Computer Science 2020-04-13 Yanchao Yang , Dong Lao , Ganesh Sundaramoorthi , Stefano Soatto