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Biomedical research increasingly relies on integrating diverse data modalities, including gene expression profiles, medical images, and clinical metadata. While medical images and clinical metadata are routinely collected in clinical…

Artificial Intelligence · Computer Science 2026-01-23 Francesca Pia Panaccione , Carlo Sgaravatti , Pietro Pinoli

Generative adversarial networks (GANs) are successful deep generative models. GANs are based on a two-player minimax game. However, the objective function derived in the original motivation is changed to obtain stronger gradients when…

Machine Learning · Statistics 2016-11-10 Masatoshi Uehara , Issei Sato , Masahiro Suzuki , Kotaro Nakayama , Yutaka Matsuo

Recent advancement in generative models have demonstrated remarkable performance across various data modalities. Beyond their typical use in data synthesis, these models play a crucial role in distribution matching tasks such as latent…

Machine Learning · Computer Science 2025-08-19 Sagar Shrestha , Rajesh Shrestha , Tri Nguyen , Subash Timilsina

Through the probing of light-matter interactions, Raman spectroscopy provides invaluable insights into the composition, structure, and dynamics of materials, and obtaining such data from portable and cheap instruments is of immense…

Chemical Physics · Physics 2024-07-03 Vikas Yadav , Abhay Kumar Tiwari , Soumik Siddhanta

Despite the remarkable success of generative adversarial networks, their performance seems less impressive for diverse training sets, requiring learning of discontinuous mapping functions. Though multi-mode prior or multi-generator models…

Computer Vision and Pattern Recognition · Computer Science 2019-09-17 Jogendra Nath Kundu , Maharshi Gor , Dakshit Agrawal , R. Venkatesh Babu

Generative adversarial networks (GANs) are challenging to train stably, and a promising remedy of injecting instance noise into the discriminator input has not been very effective in practice. In this paper, we propose Diffusion-GAN, a…

Machine Learning · Computer Science 2023-08-29 Zhendong Wang , Huangjie Zheng , Pengcheng He , Weizhu Chen , Mingyuan Zhou

Generative Adversarial Network (GAN) and its variants have recently attracted intensive research interests due to their elegant theoretical foundation and excellent empirical performance as generative models. These tools provide a promising…

Machine Learning · Computer Science 2018-02-20 Liyang Xie , Kaixiang Lin , Shu Wang , Fei Wang , Jiayu Zhou

Generative adversarial networks (GANs) are able to model the complex highdimensional distributions of real-world data, which suggests they could be effective for anomaly detection. However, few works have explored the use of GANs for the…

Machine Learning · Computer Science 2019-05-03 Houssam Zenati , Chuan Sheng Foo , Bruno Lecouat , Gaurav Manek , Vijay Ramaseshan Chandrasekhar

Generative adversarial nets (GANs) have been remarkably successful at learning to sample from distributions specified by a given dataset, particularly if the given dataset is reasonably large compared to its dimensionality. However, given…

Machine Learning · Computer Science 2022-11-29 Tiantian Fang , Ruoyu Sun , Alex Schwing

Dual discriminator generative adversarial networks (D2 GANs) were introduced to mitigate the problem of mode collapse in generative adversarial networks. In D2 GANs, two discriminators are employed alongside a generator: one discriminator…

Machine Learning · Computer Science 2025-07-24 Penukonda Naga Chandana , Tejas Srivastava , Gowtham R. Kurri , V. Lalitha

Two recently introduced criteria for estimation of generative models are both based on a reduction to binary classification. Noise-contrastive estimation (NCE) is an estimation procedure in which a generative model is trained to be able to…

Machine Learning · Statistics 2015-05-22 Ian J. Goodfellow

Generative adversarial networks (GANs) have been extremely effective in approximating complex distributions of high-dimensional, input data samples, and substantial progress has been made in understanding and improving GAN performance in…

Machine Learning · Computer Science 2018-05-01 Daniel Jiwoong Im , He Ma , Graham Taylor , Kristin Branson

Generative adversarial networks (GANs) have been a popular deep generative model for real-world applications. Despite many recent efforts on GANs that have been contributed, mode collapse and instability of GANs are still open problems…

Computer Vision and Pattern Recognition · Computer Science 2021-03-24 Shiming Chen , Wenjie Wang , Beihao Xia , Xinge You , Zehong Cao , Weiping Ding

Data scarcity and class imbalance are two fundamental challenges in many machine learning applications to healthcare. Breast cancer classification in mammography exemplifies these challenges, with a malignancy rate of around 0.5% in a…

Image and Video Processing · Electrical Eng. & Systems 2020-06-02 Eric Wu , Kevin Wu , William Lotter

With surge of available but unlabeled data, Positive Unlabeled (PU) learning is becoming a thriving challenge. This work deals with this demanding task for which recent GAN-based PU approaches have demonstrated promising results. Generative…

Computer Vision and Pattern Recognition · Computer Science 2019-10-07 Florent Chiaroni , Ghazaleh Khodabandelou , Mohamed-Cherif Rahal , Nicolas Hueber , Frederic Dufaux

Research on generalization bounds for deep networks seeks to give ways to predict test error using just the training dataset and the network parameters. While generalization bounds can give many insights about architecture design, training…

Machine Learning · Computer Science 2022-03-21 Yi Zhang , Arushi Gupta , Nikunj Saunshi , Sanjeev Arora

We introduce effective training algorithms for Generative Adversarial Networks (GAN) to alleviate mode collapse and gradient vanishing. In our system, we constrain the generator by an Autoencoder (AE). We propose a formulation to consider…

Computer Vision and Pattern Recognition · Computer Science 2018-12-18 Ngoc-Trung Tran , Tuan-Anh Bui , Ngai-Man Cheung

Magnetic Resonance Imaging (MRI) of the brain has been used to investigate a wide range of neurological disorders, but data acquisition can be expensive, time-consuming, and inconvenient. Multi-site studies present a valuable opportunity to…

Computer Vision and Pattern Recognition · Computer Science 2018-04-13 Harrison Nguyen , Richard W. Morris , Anthony W. Harris , Mayuresh S. Korgoankar , Fabio Ramos

Generative Adversarial Networks (GANs) are proficient at generating synthetic data but continue to suffer from mode collapse, where the generator produces a narrow range of outputs that fool the discriminator but fail to capture the full…

Machine Learning · Computer Science 2025-11-03 Mahsa Valizadeh , Rui Tuo , James Caverlee

Distributional causal inference requires estimating not only average treatment effects but also interventional outcome distributions, including quantiles, tail risks, and policy-dependent uncertainty. As a method for distributional causal…

Statistics Theory · Mathematics 2026-05-12 Shu Tamano , Masaaki Imaizumi