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Medical imaging diagnosis increasingly relies on Machine Learning (ML) models. This is a task that is often hampered by severely imbalanced datasets, where positive cases can be quite rare. Their use is further compromised by their limited…

Machine Learning · Computer Science 2024-01-26 Yumnah Hasan , Allan de Lima , Fatemeh Amerehi , Darian Reyes Fernandez de Bulnes , Patrick Healy , Conor Ryan

Accurate detection of cancer tissue regions (CTR) enables deeper analysis of the tumor microenvironment and offers crucial insights into treatment response. Traditional CTR detection methods, which typically rely on the rich cellular…

Computer Vision and Pattern Recognition · Computer Science 2026-03-09 Shuailin Xue , Jun Wan , Lihua Zhang , Wenwen Min

The data volume generated by astronomical surveys is growing rapidly. Traditional analysis techniques in spectroscopy either demand intensive human interaction or are computationally expensive. In this scenario, machine learning, and…

Instrumentation and Methods for Astrophysics · Physics 2018-05-09 Rafael Garcia-Dias , Carlos Allende Prieto , Jorge Sánchez Almeida , Ignacio Ordovás-Pascual

Artificial Intelligence (AI) can potentially support histopathologists in the diagnosis of a broad spectrum of cancer types. In colorectal cancer (CRC), AI can alleviate the laborious task of characterization and reporting on resected…

Image and Video Processing · Electrical Eng. & Systems 2023-02-10 John-Melle Bokhorst , Iris D. Nagtegaal , Filippo Fraggetta , Simona Vatrano , Wilma Mesker , Michael Vieth , Jeroen van der Laak , Francesco Ciompi

Reverse-phase protein array (RPPA) analysis is a powerful, relatively new platform that allows for high-throughput, quantitative analysis of protein networks. One of the challenges that currently limit the potential of this technology is…

Sparse principal component analysis (PCA) and sparse canonical correlation analysis (CCA) are two essential techniques from high-dimensional statistics and machine learning for analyzing large-scale data. Both problems can be formulated as…

Machine Learning · Statistics 2019-03-28 Shixiang Chen , Shiqian Ma , Lingzhou Xue , Hui Zou

The sparse representation classifier (SRC) has been utilized in various classification problems, which makes use of L1 minimization and works well for image recognition satisfying a subspace assumption. In this paper we propose a new…

Machine Learning · Statistics 2024-06-27 Cencheng Shen , Li Chen , Yuexiao Dong , Carey E. Priebe

Cervical cancer is a crucial global health concern for women, and the persistent infection of High-risk HPV mainly triggers this remains a global health challenge, with young women diagnosis rates soaring from 10\% to 40\% over three…

Image and Video Processing · Electrical Eng. & Systems 2024-08-21 Tatsuhiro Baba , Abu Saleh Musa Miah , Jungpil Shin , Md. Al Mehedi Hasan

Sparse representation-based classification (SRC) has been shown to achieve a high level of accuracy in face recognition (FR). However, matching faces captured in unconstrained video against a gallery with a single reference facial still per…

Computer Vision and Pattern Recognition · Computer Science 2019-10-08 Fania Mokhayeri , Eric Granger

The existing barely-supervised medical image segmentation (BSS) methods, adopting a registration-segmentation paradigm, aim to learn from data with very few annotations to mitigate the extreme label scarcity problem. However, this paradigm…

Computer Vision and Pattern Recognition · Computer Science 2024-07-09 Junming Su , Zhiqiang Shen , Peng Cao , Jinzhu Yang , Osmar R. Zaiane

Computational antibody design has seen rapid methodological progress, with dozens of deep generative methods proposed in the past three years, yet the field lacks a standardized benchmark for fair comparison and model development. These…

Machine Learning · Computer Science 2026-04-02 Mansoor Ahmed , Nadeem Taj , Imdad Ullah Khan , Hemanth Venkateswara , Murray Patterson

Deep neural networks have reached remarkable achievements in medical image processing tasks, specifically in classifying and detecting various diseases. However, when confronted with limited data, these networks face a critical…

Computer Vision and Pattern Recognition · Computer Science 2024-09-25 Matina Mahdizadeh Sani , Ali Royat , Mahdieh Soleymani Baghshah

Robust automated organ segmentation is a prerequisite for computer-aided diagnosis (CAD), quantitative imaging analysis and surgical assistance. For high-variability organs such as the pancreas, previous approaches report undesirably low…

Computer Vision and Pattern Recognition · Computer Science 2016-03-08 Amal Farag , Le Lu , Holger R. Roth , Jiamin Liu , Evrim Turkbey , Ronald M. Summers

Accurate polyp segmentation is of great significance for the diagnosis and treatment of colorectal cancer. However, it has always been very challenging due to the diverse shape and size of polyp. In recent years, state-of-the-art methods…

Computer Vision and Pattern Recognition · Computer Science 2023-01-13 Ruifei Zhang , Guanbin Li , Zhen Li , Shuguang Cui , Dahong Qian , Yizhou Yu

We investigate the performance on phoneme categorization and phoneme and word segmentation of several self-supervised learning (SSL) methods based on Contrastive Predictive Coding (CPC). Our experiments show that with the existing…

Early detection of lung cancer is critical for improvement of patient survival. To address the clinical need for efficacious treatments, genetically engineered mouse models (GEMM) have become integral in identifying and evaluating the…

Kernel Principal Component Analysis (KPCA) is a popular dimensionality reduction technique with a wide range of applications. However, it suffers from the problem of poor scalability. Various approximation methods have been proposed in the…

Machine Learning · Computer Science 2017-12-13 Deena P. Francis , Kumudha Raimond

Deep learning enables the modelling of high-resolution histopathology whole-slide images (WSI). Weakly supervised learning of tile-level data is typically applied for tasks where labels only exist on the patient or WSI level (e.g. patient…

Image and Video Processing · Electrical Eng. & Systems 2025-06-09 Abhinav Sharma , Bojing Liu , Mattias Rantalainen

Automated detection and classification of cervical cells in conventional Pap smear images can strengthen cervical cancer screening at scale by reducing manual workload, improving triage, and increasing consistency across readers. However,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-26 Lautaro Kogan , María Victoria Ríos

Histopathology image analysis plays a critical role in cancer diagnosis and treatment. To automatically segment the cancerous regions, fully supervised segmentation algorithms require labor-intensive and time-consuming labeling at the pixel…

Image and Video Processing · Electrical Eng. & Systems 2019-08-29 Gang Xu , Zhigang Song , Zhuo Sun , Calvin Ku , Zhe Yang , Cancheng Liu , Shuhao Wang , Jianpeng Ma , Wei Xu