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Certain cancer types, notably pancreatic cancer, are difficult to detect at an early stage, motivating robust biomarker-based screening. Liquid biopsies enable non-invasive monitoring of circulating biomarkers, but typical machine learning…

Machine Learning · Computer Science 2025-11-21 Chongmin Lee , Jihie Kim

Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related deaths worldwide. Several diagnostic methods, such as imaging modalities and Serum Alpha-Fetoprotein (AFP) testing, have been used for HCC detection; however,…

Genomics · Quantitative Biology 2025-07-02 Aram Ansary Ogholbake , Qiang Cheng

Sparse Representation (SR) techniques encode the test samples into a sparse linear combination of all training samples and then classify the test samples into the class with the minimum residual. The classification of SR techniques depends…

Computer Vision and Pattern Recognition · Computer Science 2019-07-01 Chun-Mei Feng , Yong Xu , Zuoyong Li , Jian Yang

This work studies estimation of sparse principal components in high dimensions. Specifically, we consider a class of estimators based on kernel PCA, generalizing the covariance thresholding algorithm proposed by Krauthgamer et al. (2015).…

Statistics Theory · Mathematics 2025-04-10 Michael J. Feldman , Theodor Misiakiewicz , Elad Romanov

We propose a novel architecture and method of explainable classification with Concept Bottleneck Models (CBMs). While SOTA approaches to Image Classification task work as a black box, there is a growing demand for models that would provide…

Computer Vision and Pattern Recognition · Computer Science 2024-04-05 Andrei Semenov , Vladimir Ivanov , Aleksandr Beznosikov , Alexander Gasnikov

It has always been a big challenge to identify subtle changes in Electroencephalogram (EEG) signals. Minor differences often lead to vital decisions, for example, which grade a certain tumour belong to or whether a haemorrhage can result in…

Systems and Control · Electrical Eng. & Systems 2022-06-01 Debojyoti Seth

Simultaneous segmentation and classification of nuclei in digital histology play an essential role in computer-assisted cancer diagnosis; however, it remains challenging. The highest achieved binary and multi-class Panoptic Quality (PQ)…

Computer Vision and Pattern Recognition · Computer Science 2024-04-29 Ibtihaj Ahmad , Syed Muhammad Israr , Zain Ul Islam

In this paper, we propose a novel information theoretic framework for dictionary learning (DL) and sparse coding (SC) on a statistical manifold (the manifold of probability distributions). Unlike the traditional DL and SC framework, our new…

Computer Vision and Pattern Recognition · Computer Science 2018-05-08 Rudrasis Chakraborty , Monami Banerjee , Baba C. Vemuri

We propose a generalized Sparse Representation- based Classification (SRC) algorithm for open set recognition where not all classes presented during testing are known during training. The SRC algorithm uses class reconstruction errors for…

Computer Vision and Pattern Recognition · Computer Science 2017-05-09 He Zhang , Vishal M. Patel

We consider the image classification problem via kernel collaborative representation classification with locality constrained dictionary (KCRC-LCD). Specifically, we propose a kernel collaborative representation classification (KCRC)…

Computer Vision and Pattern Recognition · Computer Science 2014-10-20 Weiyang Liu , Zhiding Yu , Lijia Lu , Yandong Wen , Hui Li , Yuexian Zou

Labeled speech data from patients with Parkinsons disease (PD) are scarce, and the statistical distributions of training and test data differ significantly in the existing datasets. To solve these problems, dimensional reduction and sample…

Machine Learning · Computer Science 2020-02-11 Xiaoheng Zhang , Yongming Li , Pin Wang , Xiaoheng Tan , Yuchuan Liu

Ovarian cancer (OC) is one of the most prevalent types of cancer in women. Early and accurate diagnosis is crucial for the survival of the patients. However, the majority of women are diagnosed in advanced stages due to the lack of…

Machine Learning · Computer Science 2024-07-31 Asif Newaz , Abdullah Taharat , Md Sakibul Islam , A. G. M. Fuad Hasan Akanda

We introduce a novel nonlinear model, Sparse Adaptive Bottleneck Centroid-Encoder (SABCE), for determining the features that discriminate between two or more classes. The algorithm aims to extract discriminatory features in groups while…

Machine Learning · Computer Science 2023-06-12 Tomojit Ghosh , Michael Kirby

Sparse matrices, more specifically SpGEMM kernels, are commonly found in a wide range of applications, spanning graph-based path-finding to machine learning algorithms (e.g., neural networks). A particular challenge in implementing SpGEMM…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-06-01 Kaustubh Shivdikar

In cancer research, high-throughput profiling has been extensively conducted. In recent studies, the integrative analysis of data on multiple cancer patient groups/subgroups has been conducted. Such analysis has the potential to reveal the…

Methodology · Statistics 2022-12-01 Yifan Sun , Zhengyang Sun , Yu Jiang , Yang Li , Shuangge Ma

Background: High-throughput proteomics techniques, such as mass spectrometry (MS)-based approaches, produce very high-dimensional data-sets. In a clinical setting one is often interested in how mass spectra differ between patients of…

The CANDECOMP/PARAFAC (or Canonical polyadic, CP) decomposition of tensors has numerous applications in various fields, such as chemometrics, signal processing, machine learning, etc. Tensor CP decomposition assumes the knowledge of the…

Numerical Analysis · Mathematics 2025-01-08 Zihao Wang , Minru Bai , Liang Chen , Xueying Zhao

Recent advances suggest that a wide range of computer vision problems can be addressed more appropriately by considering non-Euclidean geometry. This paper tackles the problem of sparse coding and dictionary learning in the space of…

Machine Learning · Computer Science 2013-04-17 Mehrtash T. Harandi , Conrad Sanderson , Richard Hartley , Brian C. Lovell

In this work, we propose a novel information theoretic framework for dictionary learning (DL) and sparse coding (SC) on a statistical manifold (the manifold of probability distributions). Unlike the traditional DL and SC framework, our new…

Computer Vision and Pattern Recognition · Computer Science 2017-02-06 Rudrasis Chakraborty , Monami Banerjee , Victoria Crawford , Baba C. Vemuri

We propose an evaluation framework for class probability estimates (CPEs) in the presence of label uncertainty, which is commonly observed as diagnosis disagreement between experts in the medical domain. We also formalize evaluation metrics…

Machine Learning · Statistics 2021-03-23 Takahiro Mimori , Keiko Sasada , Hirotaka Matsui , Issei Sato