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Although DNA foundation models have advanced the understanding of genomes, they still face significant challenges in the limited scale and diversity of genomic data. This limitation starkly contrasts with the success of natural language…

Genomics · Quantitative Biology 2024-02-14 Huixin Zhan , Ying Nian Wu , Zijun Zhang

Continuously-growing data volumes lead to larger generic models. Specific use-cases are usually left out, since generic models tend to perform poorly in domain-specific cases. Our work addresses this gap with a method for selecting…

Computation and Language · Computer Science 2022-02-08 Javad Pourmostafa Roshan Sharami , Dimitar Shterionov , Pieter Spronck

Contextual embedding-based language models trained on large data sets, such as BERT and RoBERTa, provide strong performance across a wide range of tasks and are ubiquitous in modern NLP. It has been observed that fine-tuning these models on…

Computation and Language · Computer Science 2021-09-16 Vin Sachidananda , Jason S. Kessler , Yi-an Lai

Collecting high-quality training data is essential for fine-tuning Large Language Models (LLMs). However, acquiring such data is often costly and time-consuming, especially for non-English languages such as Italian. Recently, researchers…

Computation and Language · Computer Science 2025-04-01 Fatemeh Mohammadi , Tommaso Romano , Samira Maghool , Paolo Ceravolo

Large Language Models (LLMs) fine-tuned for specific domains exhibit strong performance; however, the underlying mechanisms by which this fine-tuning reshapes their parametric space are not well understood. Prior works primarily focus on…

Computation and Language · Computer Science 2025-10-13 Eshaan Tanwar , Deepak Nathani , William Yang Wang , Tanmoy Chakraborty

The introduction of Large Language Models (LLMs), and the vast volume of publicly available medical data, amplified the application of NLP to the medical domain. However, LLMs are pretrained on data that are not explicitly relevant to the…

Computation and Language · Computer Science 2023-12-12 Chris Solomou

In data-rich domains such as vision, language, and speech, deep learning prevails to deliver high-performance task-specific models and can even learn general task-agnostic representations for efficient finetuning to downstream tasks.…

Machine Learning · Computer Science 2023-12-07 Pin-Yu Chen

Cross-lingual model transfer is a compelling and popular method for predicting annotations in a low-resource language, whereby parallel corpora provide a bridge to a high-resource language and its associated annotated corpora. However,…

Computation and Language · Computer Science 2017-05-02 Meng Fang , Trevor Cohn

The efficacy of large language models (LLMs) is heavily dependent on the quality of the underlying data, particularly within specialized domains. A common challenge when fine-tuning LLMs for domain-specific applications is the potential…

Computation and Language · Computer Science 2024-03-15 Jianwei Sun , Chaoyang Mei , Linlin Wei , Kaiyu Zheng , Na Liu , Ming Cui , Tianyi Li

Biomedical text mining is becoming increasingly important as the number of biomedical documents rapidly grows. With the progress in natural language processing (NLP), extracting valuable information from biomedical literature has gained…

Computation and Language · Computer Science 2019-10-21 Jinhyuk Lee , Wonjin Yoon , Sungdong Kim , Donghyeon Kim , Sunkyu Kim , Chan Ho So , Jaewoo Kang

This paper narrows the performance gap between small, specialized models and significantly larger general-purpose models through domain adaptation via continual pre-training and merging. We address the scarcity of specialized non-English…

Computation and Language · Computer Science 2026-04-22 Niclas Doll , Jasper Schulze Buschhoff , Shalaka Satheesh , Hammam Abdelwahab , Héctor Allende-Cid , Katrin Klug

Analyzing vast textual data and summarizing key information from electronic health records imposes a substantial burden on how clinicians allocate their time. Although large language models (LLMs) have shown promise in natural language…

Multimodal large language models (MLLMs) have shown remarkable capabilities in multimodal perception and understanding tasks. However, their effectiveness in specialized domains, such as remote sensing and medical imaging, remains limited.…

Computation and Language · Computer Science 2026-02-05 Qinglong Cao , Yuntian Chen , Chao Ma , Xiaokang Yang

Adapter layers are lightweight, learnable units inserted between transformer layers. Recent work explores using such layers for neural machine translation (NMT), to adapt pre-trained models to new domains or language pairs, training only a…

Computation and Language · Computer Science 2021-10-20 Asa Cooper Stickland , Alexandre Bérard , Vassilina Nikoulina

Deep Learning has thrived on the emergence of biomedical big data. However, medical datasets acquired at different institutions have inherent bias caused by various confounding factors such as operation policies, machine protocols,…

Image and Video Processing · Electrical Eng. & Systems 2019-11-15 Yundong Zhang , Hang Wu , Huiye Liu , Li Tong , May D Wang

Machine learning techniques used in computer-aided medical image analysis usually suffer from the domain shift problem caused by different distributions between source/reference data and target data. As a promising solution, domain…

Computer Vision and Pattern Recognition · Computer Science 2021-10-26 Hao Guan , Mingxia Liu

The primary aim of this research was to address the limitations observed in the medical knowledge of prevalent large language models (LLMs) such as ChatGPT, by creating a specialized language model with enhanced accuracy in medical advice.…

Computation and Language · Computer Science 2023-06-27 Yunxiang Li , Zihan Li , Kai Zhang , Ruilong Dan , Steve Jiang , You Zhang

Language models pretrained on text from a wide variety of sources form the foundation of today's NLP. In light of the success of these broad-coverage models, we investigate whether it is still helpful to tailor a pretrained model to the…

Computation and Language · Computer Science 2020-05-07 Suchin Gururangan , Ana Marasović , Swabha Swayamdipta , Kyle Lo , Iz Beltagy , Doug Downey , Noah A. Smith

Pre-training large-scale neural language models on raw texts has made a significant contribution to improving transfer learning in natural language processing (NLP). With the introduction of transformer-based language models, such as…

Computation and Language · Computer Science 2024-05-08 Shoya Wada , Toshihiro Takeda , Shiro Manabe , Shozo Konishi , Jun Kamohara , Yasushi Matsumura

The application of large language models (LLMs) in healthcare has gained significant attention due to their ability to process complex medical data and provide insights for clinical decision-making. These models have demonstrated…

Computer Vision and Pattern Recognition · Computer Science 2024-09-26 Amna Khalid , Ayma Khalid , Umar Khalid
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