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Large language models (LLMs) can capture rich representations of concepts that are useful for real-world tasks. However, language alone is limited. While existing LLMs excel at text-based inferences, health applications require that models…

Computation and Language · Computer Science 2023-05-26 Xin Liu , Daniel McDuff , Geza Kovacs , Isaac Galatzer-Levy , Jacob Sunshine , Jiening Zhan , Ming-Zher Poh , Shun Liao , Paolo Di Achille , Shwetak Patel

Large Language Models (LLMs) have shown promising results on machine translation for high resource language pairs and domains. However, in specialised domains (e.g. medical) LLMs have shown lower performance compared to standard neural…

Computation and Language · Computer Science 2025-07-31 Miguel Rios

Biomedical question-answering (QA) has gained increased attention for its capability to provide users with high-quality information from a vast scientific literature. Although an increasing number of biomedical QA datasets has been recently…

Computation and Language · Computer Science 2021-02-17 Gabriele Pergola , Elena Kochkina , Lin Gui , Maria Liakata , Yulan He

Large language models (LLMs) have shown potential in biomedical applications, leading to efforts to fine-tune them on domain-specific data. However, the effectiveness of this approach remains unclear. This study evaluates the performance of…

Most biomedical pretrained language models are monolingual and cannot handle the growing cross-lingual requirements. The scarcity of non-English domain corpora, not to mention parallel data, poses a significant hurdle in training…

Computation and Language · Computer Science 2023-11-21 Lei Geng , Xu Yan , Ziqiang Cao , Juntao Li , Wenjie Li , Sujian Li , Xinjie Zhou , Yang Yang , Jun Zhang

The insertion of deep learning in medical image analysis had lead to the development of state-of-the art strategies in several applications such a disease classification, as well as abnormality detection and segmentation. However, even the…

Image and Video Processing · Electrical Eng. & Systems 2022-02-24 Mauricio Orbes-Arteaga , Thomas Varsavsky , Lauge Sorensen , Mads Nielsen , Akshay Pai , Sebastien Ourselin , Marc Modat , M Jorge Cardoso

The development of medical vision-language foundation models has attracted significant attention in the field of medicine and healthcare due to their promising prospect in various clinical applications. While previous studies have commonly…

Computer Vision and Pattern Recognition · Computer Science 2024-02-27 Weijian Huang , Cheng Li , Hong-Yu Zhou , Jiarun Liu , Hao Yang , Yong Liang , Guangming Shi , Hairong Zheng , Shanshan Wang

The biomedical field relies heavily on concept linking in various areas such as literature mining, graph alignment, information retrieval, question-answering, data, and knowledge integration. Although large language models (LLMs) have made…

Computation and Language · Computer Science 2023-07-04 Qinyong Wang , Zhenxiang Gao , Rong Xu

Multi-modal data abounds in biomedicine, such as radiology images and reports. Interpreting this data at scale is essential for improving clinical care and accelerating clinical research. Biomedical text with its complex semantics poses…

Domain shift is a significant challenge in machine learning, particularly in medical applications where data distributions differ across institutions due to variations in data collection practices, equipment, and procedures. This can…

Machine Learning · Computer Science 2025-06-30 Takumi Okuo , Shinnosuke Matsuo , Shota Harada , Kiyohito Tanaka , Ryoma Bise

Several biomedical language models have already been developed for clinical language inference. However, these models typically utilize general vocabularies and are trained on relatively small clinical corpora. We sought to evaluate the…

Computation and Language · Computer Science 2022-10-14 Madhumita Sushil , Dana Ludwig , Atul J. Butte , Vivek A. Rudrapatna

Large language models (LLMs) hold promise for transforming healthcare, from streamlining administrative and clinical workflows to enriching patient engagement and advancing clinical decision-making. However, their successful integration…

Computers and Society · Computer Science 2025-04-04 Mohammed Al-Garadi , Tushar Mungle , Abdulaziz Ahmed , Abeed Sarker , Zhuqi Miao , Michael E. Matheny

Biomedical Question Answering aims to obtain an answer to the given question from the biomedical domain. Due to its high requirement of biomedical domain knowledge, it is difficult for the model to learn domain knowledge from limited…

Computation and Language · Computer Science 2022-06-29 Yuxuan Lu , Jingya Yan , Zhixuan Qi , Zhongzheng Ge , Yongping Du

Current machine learning methods for medical image analysis primarily focus on developing models tailored for their specific tasks, utilizing data within their target domain. These specialized models tend to be data-hungry and often exhibit…

Image and Video Processing · Electrical Eng. & Systems 2024-07-08 Ece Ozkan , Xavier Boix

Biomedical machine reading comprehension (biomedical-MRC) aims to comprehend complex biomedical narratives and assist healthcare professionals in retrieving information from them. The high performance of modern neural network-based MRC…

Computation and Language · Computer Science 2022-07-27 Maria Mahbub , Sudarshan Srinivasan , Edmon Begoli , Gregory D Peterson

Adhering to explicit length constraints, such as generating text with a precise word count, remains a significant challenge for Large Language Models (LLMs). This study aims at investigating the differences between foundation models and…

Computation and Language · Computer Science 2025-09-03 Elisabetta Rocchetti , Alfio Ferrara

Pre-trained language models (PLMs) have been the de facto paradigm for most natural language processing (NLP) tasks. This also benefits biomedical domain: researchers from informatics, medicine, and computer science (CS) communities propose…

Computation and Language · Computer Science 2023-07-18 Benyou Wang , Qianqian Xie , Jiahuan Pei , Zhihong Chen , Prayag Tiwari , Zhao Li , Jie fu

Despite the continuous research and evolution of language models, they sometimes underperform previous versions. Existing approaches to overcome these challenges are resource-intensive, highlighting the need for alternatives that enable…

Computation and Language · Computer Science 2026-02-19 Namkyung Yoon , Kyeonghyun Yoo , Wooyong Jung , Sanghong Kim , Hwangnam Kim

Large Language Models (LLMs) have recently exploded in popularity, often matching or outperforming human abilities on many tasks. One of the key factors in training LLMs is the availability and curation of high-quality data. Data quality is…

Computation and Language · Computer Science 2025-11-04 Vlad Negoita , Mihai Masala , Traian Rebedea

Large Language Models (LLMs) have demonstrated surprising performance across various natural language processing tasks. Recently, medical LLMs enhanced with domain-specific knowledge have exhibited excellent capabilities in medical…

Computation and Language · Computer Science 2024-09-24 Jinqiang Wang , Huansheng Ning , Yi Peng , Qikai Wei , Daniel Tesfai , Wenwei Mao , Tao Zhu , Runhe Huang